The end of the beginning for hepatitis C treatment

Hepatology

Volumn 55, Issue 3, 2012, Pages 664-665

  Dieterich, Douglas ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; ASUNAPREVIR; BI 201727; BI 207127; BOCEPREVIR; DACLATASVIR; DANOPREVIR; GS 9256; MACROGOL; MERICITABINE; RIBAVIRIN; RITONAVIR; SERINE PROTEINASE INHIBITOR; TEGOBUVIR; TELAPREVIR; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIVIRAL THERAPY; GENOTYPE; HEPATITIS C; HUMAN; MUTATION; NOTE; PRIORITY JOURNAL; TREATMENT RESPONSE; VIRUS LOAD;

ANTIVIRAL AGENTS; ENZYME INHIBITORS; FEMALE; HEPACIVIRUS; HEPATITIS C; HUMANS; IMIDAZOLES; INTERFERON-ALPHA; MALE; POLYETHYLENE GLYCOLS; PROTEASE INHIBITORS; RECOMBINANT PROTEINS; RIBAVIRIN; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84857398810     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25528     Document Type: Note

References (9)

1. Chayama, K Takahashi S, Toyota J, Karino Y, Ikeda K, Ishikawa H, et al. Dual therapy with the NS5A inhibitor BMS-790052 and the NS3 protease inhibitor BMS-650032 in HCV genotype 1b-infected null responders HEPATOLOGY 2012; 55: 742-748.
2. Zeuzem S, Bruggish P, Agarwal K, Marcellin P, Sereni D, Klinker H, et al. The protease inhibitor GS-9256 and non-nucleoside polymerase inhibitor tegobuvir alone, with RBV or peginterferon plus RBV in hepatitis. HEPATOLOGY 2012; 55: 749-758.
3. Gane E, Roberts S, Stedman C, Angus P, Ritchie B, Elston R, et al. Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomized, double-blind, placebo-controlled, dose-escalation trial. Lancet 2010; 376: 1467-1475.
4. Thomas E, Feld J, Li Z, Hu Z, Fried MW, Liang TJ. Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis c virus cell culture models. HEPATOLOGY 2011; 53: 32-41.
5. Sarazin D, Zeuzem S. Resistance to direct acting antiviral agents in patients with hepatitis C virus infection. Gastroenterology 2010; 138: 447-462.
6. Zeuzem S, Asselah T, Angus P, Zarski JP, Larrey D, Mullhaupt B, et al. Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127 and ribavirin in patients with chronic HCV infection. Gastroenterology 2011; 141: 2047-2055.
7. clinical trials.gov.
8. Lok A, Gardiner D, Lawitz E, Martorell C, Everson G, Ghalil R, et al. Quadruple therapy with BMS-790052 and BMS-650032 and peg-IFN/RBV for 24 weeks results in 100% SVR in HCV genotype 1 null responders J Hepatol 2012; 55:742-748.
9. Paul E. It is indeed the cup, from "The Quest of the Saint Graal." In: West M. Claire de Lune and Other Troubadour Romances. Music by Alfred Mereer. London: G.G. Harrap; 1913.