메뉴 건너뛰기




Volumn 22, Issue SUPPL.8, 2011, Pages 61-64

Update of randomized trials in recurrent disease

Author keywords

Cancer; Ovarian; Randomized; Relapse; Review

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; CANFOSFAMIDE; CARBOPLATIN; CEDIRANIB; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPOTHILONE B; ETIRINOTECAN PEGOL; GEMCITABINE; NINTEDANIB; OLAPARIB; PACLITAXEL; PLACEBO; PLEVITREXED; SARACATINIB; SORAFENIB; TAMOXIFEN; TEMOZOLOMIDE; THALIDOMIDE; TOPOTECAN; TRABECTEDIN; TREBANANIB; TREOSULFAN; UNINDEXED DRUG; VELIPARIB; VINTAFOLIDE; VISMODEGIB; ANTINEOPLASTIC AGENT;

EID: 84857396102     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdr518     Document Type: Conference Paper
Times cited : (21)

References (33)
  • 1
    • 0034064719 scopus 로고    scopus 로고
    • Oxaliplatin or paclitaxel in patients withplatinum-pretreated advanced ovarian cancer: a randomized phase II study ofthe European Organization for Research and Treatment of Cancer GynecologyGroup
    • Piccart MJ, Green JA, Lacave AJ et al. Oxaliplatin or paclitaxel in patients with platinum-pretreated advanced ovarian cancer: a randomized phase II study of the European Organization for Research and Treatment of Cancer Gynecology Group. J Clin Oncol 2000; 18: 1193-1202.
    • (2000) J Clin Oncol , vol.18 , pp. 1193-1202
    • Piccart, M.J.1    Green, J.A.2    Lacave, A.J.3
  • 2
    • 0942287951 scopus 로고    scopus 로고
    • International Topotecan Study Group.LOng-term survival in a phase III, randomised study of topotecan versus paclitaxel in advanced epithelial ovarian carcinoma
    • Ten Bokkel Huinink W, Lane SR, Ross GA. International Topotecan Study Group.Long-term survival in a phase III, randomised study of topotecan versus paclitaxel advanced epithelial ovarian carcinoma. Ann Oncol 2004; 15: 100-103.
    • (2004) Ann Oncol , vol.15 , pp. 100-103
    • Ten Bokkel Huinink, W.1    Lane, S.R.2    Ross, G.A.3
  • 3
    • 4644225190 scopus 로고    scopus 로고
    • Doxil Study 30-49 Investigators. Long-termsurvival advantage for women treated with pegylated liposomal doxorubicincompared with topotecan in a phase 3 randomized study of recurrent andrefractory epithelial ovarian cancer
    • Gordon AN, Tonda M, Sun S et al. Doxil Study 30-49 Investigators. Long-termsurvival advantage for women treated with pegylated liposomal doxorubicincompared with topotecan in a phase 3 randomized study of recurrent andrefractory epithelial ovarian cancer. Gynecol Oncol 2004; 95: 1-8.
    • (2004) Gynecol Oncol , vol.95 , pp. 1-8
    • Gordon, A.N.1    Tonda, M.2    Sun, S.3
  • 4
    • 0005323412 scopus 로고    scopus 로고
    • A phase III study of Doxil/Caelyx versuspaclitaxel in platinum-treated, taxane-naive relapsed ovarian cancer
    • Abstr 808
    • O'Byrne KJ, Bliss P, Graham JD et al. A phase III study of Doxil/Caelyx versus paclitaxel in platinum-treated, taxane-naive relapsed ovarian cancer. Proc AmSoc Clin Oncol 2002; 21: 203a (Abstr 808).
    • (2002) Proc AmSoc Clin Oncol , vol.21
    • O'Byrne, K.J.1    Bliss, P.2    Graham, J.D.3
  • 5
    • 84866768651 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabinecompared with pegylated liposomal doxorubicin in patients with platinumresistantovarian cancer
    • Mutch DG, Orlando M, Goss T et al. Randomized phase III trial of gemcitabinecompared with pegylated liposomal doxorubicin in patients with platinumresistantovarian cancer. J Clin Oncol 2008; 26: 890-896.
    • (2008) J Clin Oncol , vol.26 , pp. 890-896
    • Mutch, D.G.1    Orlando, M.2    Goss, T.3
  • 6
    • 84866771426 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in progressive or recurrentovarian cancer
    • Ferrandina G, Ludovisi M, Lorusso D et al. Phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in progressive or recurrentovarian cancer. J Clin Oncol 25; 19: 2811-2818.
    • J Clin Oncol , vol.25 , Issue.19 , pp. 2811-2818
    • Ferrandina, G.1    Ludovisi, M.2    Lorusso, D.3
  • 7
    • 34848870316 scopus 로고    scopus 로고
    • Topotecan versus treosulphan in earlyrecurrent ovarian cancer after primary platinum/paclitaxel chemotherapy. A prospective randomized phase III trial of the AGO Ovarian Cancer Study Group
    • Abstr 5
    • Meier W, du Bois A, Reuss A et al. Topotecan versus treosulphan in early recurrent ovarian cancer after primary platinum/paclitaxel chemotherapy. A prospective randomized phase III trial of the AGO Ovarian Cancer Study Group. Int J Gynecol Cancer 2004; 14 (Suppl 1): 2 (Abstr 5).
    • (2004) Int J Gynecol Cancer , vol.14 , Issue.SUPPL. 1 , pp. 2
    • Meier, W.1    du Bois, A.2    Reuss, A.3
  • 8
    • 68749089764 scopus 로고    scopus 로고
    • ASSIST-1 Study Group. Phase 3randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomaldoxorubicin or topotecan as third-line therapy in patients with platinum-refractoryr -resistant ovarian cancer
    • Vergote I, Finkler N, del Campo J et al. ASSIST-1 Study Group. Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomaldoxorubicin or topotecan as third-line therapy in patients with platinum-refractoryr -resistnt ovarian cancer. Eur J Cancer 2009; 45: 2324-2332.
    • (2009) Eur J Cancer , vol.45 , pp. 2324-2332
    • Vergote, I.1    Finkler, N.2    del Campo, J.3
  • 9
    • 0032903679 scopus 로고    scopus 로고
    • Paclitaxel vs epidoxorubicin plus paclitaxelas second-line therapy for platinum-refractory and -resistant ovarian cancer
    • Bolis G, Parazzini F, Scarfone G et al. Paclitaxel vs epidoxorubicin plus paclitaxelas second-line therapy for platinum-refractory and -resistant ovarian cancer. Gynecol Oncol 1999; 72: 60-64.
    • (1999) Gynecol Oncol , vol.72 , pp. 60-6410
    • Bolis, G.1    Parazzini, F.2    Scarfone, G.3
  • 10
    • 0000087270 scopus 로고    scopus 로고
    • Randomized trial comparingpaclitaxel + doxorubicin versus paclitaxel as second line therapy foradvanced ovarian cancer patients in early progression after platinum basedchemotherapy
    • Abstr 1506
    • Torri V, Floriani I, Tinazzi A et al. Randomized trial comparingpaclitaxel + doxorubicin versus paclitaxel as second line therapy foradvanced ovarian cancer patients in early progression after platinum basedchemotherapy. Proc Am Soc Clin Oncol 2000; 19: 381a (Abstr 1506).
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Torri, V.1    Floriani, I.2    Tinazzi, A.3
  • 11
    • 3042792377 scopus 로고    scopus 로고
    • Randomised controlled trial comparing singleagent paclitaxel vs epidoxorubicin plus paclitaxel in patients with advancedovarian cancer in early progression after platinum-based chemotherapy: an Italian Collaborative Study from the Mario Negri Institute, Milan, GONO (GruppoOncologico Nord Ovest) group and IOR (Istituto Oncologico Romagnolo) group.
    • Buda A, Floriani I, Rossi R et al. Randomised controlled trial comparing singleagent paclitaxel vs epidoxorubicin plus paclitaxel in patients with advancedovarian cancer in early progression after platinum-based chemotherapy: anItalian Collaborative Study from the Mario Negri Institute, Milan, GONO (GruppoOncologico Nord Ovest) group and IOR (Istituto Oncologico Romagnolo) group. BrJ Cancer 2004; 90: 2112-2117.
    • (2004) BrJ Cancer , vol.90 , pp. 2112-2117
    • Buda, A.1    Floriani, I.2    Rossi, R.3
  • 12
    • 49249130845 scopus 로고    scopus 로고
    • Nonplatinum topotecancombinations versus topotecan alone for recurrent ovarian cancer: results ofa phase III study of the North-Eastern German Society of Gynecological OncologyOvarian Cancer Study Group
    • Sehouli J, Stengel D, Oskay-Oezcelik G et al. Nonplatinum topotecancombinations versus topotecan alone for recurrent ovarian cancer: results ofa phase III study of the North-Eastern German Society of Gynecological OncologyOvarian Cancer Study Group. J Clin Oncol 2008; 26: 3176-3182.
    • (2008) J Clin Oncol , vol.26 , pp. 3176-3182
    • Sehouli, J.1    Stengel, D.2    Oskay-Oezcelik, G.3
  • 13
    • 77955491837 scopus 로고    scopus 로고
    • Trabectedin plus pegylated liposomaldoxorubicin in recurrent ovarian cancer
    • Monk BJ, Herzog TJ, Kaye SB et al. Trabectedin plus pegylated liposomaldoxorubicin in recurrent ovarian cancer. J Clin Oncol 2010; 28: 3107-3114.
    • (2010) J Clin Oncol , vol.28 , pp. 3107-3114
    • Monk, B.J.1    Herzog, T.J.2    Kaye, S.B.3
  • 14
    • 84856331988 scopus 로고    scopus 로고
    • Weekly paclitaxel as single agent or incombination with carboplatin or weekly topotecan in patients with resistant ovarian cancer the CARTAXHY randomized phase II trial from GINECO
    • May 11 [epub ahead of print] doi:10.1093/annonc/mdr149
    • Lortholary A, Largillier R, Weber B et al. Weekly paclitaxel as single agent or incombination with carboplatin or weekly topotecan in patients with resistantovarian cancer: the CARTAXHY randomized phase II trial from GINECO. AnnOncol 2011 May 11 [epub ahead of print] doi:10.1093/annonc/mdr149.
    • (2011) Ann Oncol
    • Lortholary, A.1    Largillier, R.2    Weber, B.3
  • 15
    • 0036498921 scopus 로고    scopus 로고
    • Randomized controlled trial of single-agentpaclitaxel versus cyclophosphamide, doxorubicin, and cisplatin in patients withrecurrent ovarian cancer who responded to first-line platinum-based regimens
    • CantÛ MG, Buda A, Parma G et al. Randomized controlled trial of single-agentpaclitaxel versus cyclophosphamide, doxorubicin, and cisplatin in patients withrecurrent ovarian cancer who responded to first-line platinum-based regimens.J Clin Oncol 2002; 20: 1232-1237.
    • (2002) J Clin Oncol , vol.20 , pp. 1232-1237
    • CantÛ, M.G.1    Buda, A.2    Parma, G.3
  • 16
    • 0035056323 scopus 로고    scopus 로고
    • Carboplatin alone vs carboplatin plusepidoxorubicin as second-line therapy for cisplatin- or carboplatin-sensitiveovarian cancer
    • Bolis G, Scarfone G, Giardina G et al. Carboplatin alone vs carboplatin plusepidoxorubicin as second-line therapy for cisplatin- or carboplatin-sensitiveovarian cancer. Gynecol Oncol 2001; 81: 3-9.
    • (2001) Gynecol Oncol , vol.81 , pp. 3-9
    • Bolis, G.1    Scarfone, G.2    Giardina, G.3
  • 17
    • 0037862963 scopus 로고    scopus 로고
    • Paclitaxel plus platinum-basedchemotherapy versus conventional platinum-based chemotherapy in women withrelapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial
    • Parmar MK, Ledermann JA, Colombo N et al. Paclitaxel plus platinum-basedchemotherapy versus conventional platinum-based chemotherapy in women withrelapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial. Lancet 2003; 361:2099-2106.
    • (2003) Lancet , vol.361 , pp. 2099-2106
    • Parmar, M.K.1    Ledermann, J.A.2    Colombo, N.3
  • 18
    • 20044389455 scopus 로고    scopus 로고
    • Randomized phase II trial ofcarboplatin versus paclitaxel and carboplatin in platinum-sensitive recurrentadvanced ovarian carcinoma: a GEICO (Grupo Espanol de Investigacion enCancer de Ovario) study
    • Gonzalez-Martin AJ, Calvo E, Bover I et al. Randomized phase II trial ofcarboplatin versus paclitaxel and carboplatin in platinum-sensitive recurrentadvanced ovarian carcinoma: a GEICO (Grupo Espanol de Investigacion enCancer de Ovario) study. Ann Oncol 2005; 16: 749-755.
    • (2005) Ann Oncol , vol.16 , pp. 749-755
    • Gonzalez-Martin, A.J.1    Calvo, E.2    Bover, I.3
  • 19
    • 33750588670 scopus 로고    scopus 로고
    • Gemcitabine plus carboplatin comparedwith carboplatin in patients with platinum-sensitive recurrent ovarian cancer: anintergroup trial of the AGO-OVAR, the NCIC-CTG, and the EORTC-GCG.
    • Pfisterer J, Plante M, Vergote I et al. Gemcitabine plus carboplatin comparedwith carboplatin in patients with platinum-sensitive recurrent ovarian cancer: anintergroup trial of the AGO-OVAR, the NCIC-CTG, and the EORTC-GCG. J ClinOncol 2006; 24: 4699-4707.
    • (2006) J ClinOncol , vol.24 , pp. 4699-4707
    • Pfisterer, J.1    Plante, M.2    Vergote, I.3
  • 20
    • 75749110481 scopus 로고    scopus 로고
    • Single agent carboplatin versuscarboplatin plus pegylated liposomal doxorubicin in recurrent ovarian cancer: final survival results of a SWOG (S0200) phase 3 randomized trial
    • Markman M, Moon J, Wilczynski S et al. Single agent carboplatin versuscarboplatin plus pegylated liposomal doxorubicin in recurrent ovarian cancer:final survival results of a SWOG (S0200) phase 3 randomized trial. Gynecol Oncol2010; 116: 323-325.
    • (2010) Gynecol Oncol , vol.116 , pp. 323-325
    • Markman, M.1    Moon, J.2    Wilczynski, S.3
  • 21
    • 77954726606 scopus 로고    scopus 로고
    • Pegylated liposomaldoxorubicin and carboplatin compared with paclitaxel and carboplatin forpatients with platinum-sensitive ovarian cancer in late relapse
    • Pujade-Lauraine E, Wagner U, Aavall-Lundqvist E et al. Pegylated liposomaldoxorubicin and carboplatin compared with paclitaxel and carboplatin forpatients with platinum-sensitive ovarian cancer in late relapse. J Clin Oncol2010; 28: 3323-3329.
    • (2010) J Clin Oncol , vol.28 , pp. 3323-3329
    • Pujade-Lauraine, E.1    Wagner, U.2    Aavall-Lundqvist, E.3
  • 22
    • 80053229517 scopus 로고    scopus 로고
    • OCEANS: a randomized, double-blinded,placebo-controlled phase III trial of chemotherapy with or without bevacizumab(BEV) in patients with platinum-sensitive recurrent epithelial ovarian (EOC),primary peritoneal (PPC), or fallopian tube cancer (FTC)
    • Abstr LBA 5007
    • Aghajanian C, Finkler NJ, Rutherford T. OCEANS: a randomized, double-blinded,placebo-controlled phase III trial of chemotherapy with or without bevacizumab(BEV) in patients with platinum-sensitive recurrent epithelial ovarian (EOC),primary peritoneal (PPC), or fallopian tube cancer (FTC). J Clin Oncol 2011; 29(Suppl 15): Abstr LBA 5007.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL 15
    • Aghajanian, C.1    Finkler, N.J.2    Rutherford, T.3
  • 23
    • 80053561888 scopus 로고    scopus 로고
    • Randomized phase II placebo-controlledtrial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120after chemotherapy for relapsed ovarian cancer.
    • August 22[epub ahead of print]
    • Ledermann J, Hackshaw A, Kaye S et al. Randomized phase II placebo-controlledtrial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120after chemotherapy for relapsed ovarian cancer. J Clin Oncol 2011 August 22epub ahead of print].
    • (2011) J Clin Oncol
    • Ledermann, J.1    Hackshaw, A.2    Kaye, S.3
  • 24
    • 77954522477 scopus 로고    scopus 로고
    • Randomized, double-blind, placebocontrolledphase II study of AMG 386 combined with weekly paclitaxel in patients(pts) with recurrent ovarian carcinoma
    • Abstr 5000
    • Karlan BY, Oza AM, Hansen VL et al. Randomized, double-blind, placebocontrolledphase II study of AMG 386 combined with weekly paclitaxel in patients(pts) with recurrent ovarian carcinoma. J Clin Oncol 2010; 28: 15s (Abstr 5000).
    • (2010) J Clin Oncol , vol.28
    • Karlan, B.Y.1    Oza, A.M.2    Hansen, V.L.3
  • 25
    • 84870715981 scopus 로고    scopus 로고
    • PRECEDENT: a randomized phase IItrial comparing EC145 and pegylated liposomal doxorubicin (PLD) incombination, versus PLD alone, in subjects with platinum-resistant ovariancancer
    • Abstr 5045
    • Naumann RW, Coleman RL, Burger RA et al. PRECEDENT: a randomized phase IItrial comparing EC145 and pegylated liposomal doxorubicin (PLD) incombination, versus PLD alone, in subjects with platinum-resistant ovariancancer. J Clin Oncol 2011; 29 (Suppl 15); Abstr 5045.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. 15
    • Naumann, R.W.1    Coleman, R.L.2    Burger, R.A.3
  • 26
    • 68149161777 scopus 로고    scopus 로고
    • Phase II trial of the oral PARPinhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer
    • Abstr 5500
    • Audeh MW, Penson RT, Friedlander M et al. Phase II trial of the oral PARPinhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. J ClinOncol 2009; 27 (Suppl 15); Abstr 5500.
    • (2009) J ClinOncol , vol.27 , Issue.SUPPL. 15
    • Audeh, M.W.1    Penson, R.T.2    Friedlander, M.3
  • 27
    • 79551577398 scopus 로고    scopus 로고
    • Phase II study of the oral PARP inhibitorolaparib (AZD2281) vs liposomal doxorubicin in ovarian cancer patients withBRCA1 and/or BRCA2 mutations
    • Abstr 9710
    • Kaye S, Kaufman B, Lubinski J et al. Phase II study of the oral PARP inhibitorolaparib (AZD2281) vs liposomal doxorubicin in ovarian cancer patients withBRCA1 and/or BRCA2 mutations. Ann Oncol 2010; 21 (Suppl 8); viii304-viii313(Abstr 9710).
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 8
    • Kaye, S.1    Kaufman, B.2    Lubinski, J.3
  • 28
    • 80053135643 scopus 로고    scopus 로고
    • Phase II randomized placebo-controlledstudy of olaparib (AZD2281) in patients with platinum-sensitive relapsed serousovarian cancer (PSR SOC)
    • Abstr 5003
    • Ledermann JA, Harter P, Gourley C et al. Phase II randomized placebo-controlledstudy of olaparib (AZD2281) in patients with platinum-sensitive relapsed serousovarian cancer (PSR SOC). J Clin Oncol 2011; 29 (Suppl 15); Abstr 5003.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL. 15
    • Ledermann, J.A.1    Harter, P.2    Gourley, C.3
  • 29
    • 84869226505 scopus 로고    scopus 로고
    • Results of a randomized, open-label, phaseIII trial of patupilone (P) versus pegylated liposomal doxorubicin (PLD) in taxane/platinum refractory/resistant patients with recurrent ovarian, fallopian, orperitoneal cancer: Thirty-fifth European Society for Medical Oncology Congress(Abstr 4843)
    • Colombo N, Schwartz PE, Bamias A. Results of a randomized, open-label, phase III trial of patupilone (P) versus pegylated liposomal doxorubicin (PLD) in taxane/platinum refractory/resistant patients with recurrent ovarian, fallopian, orpritoneal cancer. Thirty-fifth European Society for Medical Oncology Congress(Abstr 4843). Milan 2010.
    • (2010) Milan
    • Colombo, N.1    Schwartz, P.E.2    Bamias, A.3
  • 30
    • 77956652807 scopus 로고    scopus 로고
    • Phase II study of NKTR-102 in womenwith platinum-resistant/refractory ovarian cancer
    • Abstr 5013
    • Vergote IB, Micha JP, Pippitt CH Jr et al. Phase II study of NKTR-102 in womenwith platinum-resistant/refractory ovarian cancer. J Clin Oncol 2010; 28: 15s(Abstr 5013).
    • (2010) J Clin Oncol , vol.28
    • Vergote, I.B.1    Micha, J.P.2    Pippitt Jr., C.H.3
  • 31
    • 77954091256 scopus 로고    scopus 로고
    • Randomized phase II study ofdecitabine in combination with carboplatin compared with carboplatin alonein patients with recurrent advanced ovarian cancer
    • Abstr 5562
    • Glasspool RM, Gore M, Rustin G et al. Randomized phase II study ofdecitabine in combination with carboplatin compared with carboplatin alonein patients with recurrent advanced ovarian cancer. J Clin Oncol 2009; 27: 15s(Abstr 5562).
    • (2009) J Clin Oncol , vol.27
    • Glasspool, R.M.1    Gore, M.2    Rustin, G.3
  • 32
    • 84869214137 scopus 로고    scopus 로고
    • A phase 2, randomized, placebo-controlledstudy of Hedgehog (Hh) pathway inhibitor GDC-0449 as maintenance therapy inpatients with ovarian cancer in 2nd or 3rd complete remission (CR)
    • Thirty-fifth European Society for Medical Oncology Congress (LBA 25). (Milan)
    • Fehrenbacher L, Kaye S, Holloway R. A phase 2, randomized, placebo-controlledstudy of Hedgehog (Hh) pathway inhibitor GDC-0449 as maintenance therapy inpatients with ovarian cancer in 2nd or 3rd complete remission (CR). Thirty-fifth European Society for Medical Oncology Congress (LBA 25). Milan 2010.
    • (2010)
    • Fehrenbacher, L.1    Kaye, S.2    Holloway, R.3
  • 33
    • 78149358809 scopus 로고    scopus 로고
    • Randomized phase III trial of tamoxifen versus thalidomide in women with biochemical recurrent-only epithelial ovarian, fallopian tube or primary peritoneal carcinoma after a complete response to firstline platinum/taxane chemotherapy with an evaluation of serum vascular endothelial growth factor (VEGF): a Gynecologic Oncology Group study
    • Hurteau JA, Brady MF, Darcy KM et al. Randomized phase III trial of tamoxifen versus thalidomide in women with biochemical recurrent-only epithelial ovarian, fallopian tube or primary peritoneal carcinoma after a complete response to firstline platinum/taxane chemotherapy with an evaluation of serum vascular endothelial growth factor (VEGF): a Gynecologic Oncology Group study. Gynecol Oncol 2010; 119: 444-450.
    • (2010) Gynecol Oncol , vol.119 , pp. 444-450
    • Hurteau, J.A.1    Brady, M.F.2    Darcy, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.