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Volumn 118, Issue 9, 2012, Pages 2454-2465

Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer

Author keywords

carcinoma; IGF type 1; insulin; nonsmall cell lung; prognosis; receptor; survival

Indexed keywords

INSULIN RECEPTOR; SOMATOMEDIN C RECEPTOR; TUMOR MARKER;

EID: 84857380018     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26492     Document Type: Article
Times cited : (58)

References (38)
  • 1
    • 79960042770 scopus 로고    scopus 로고
    • Targeted therapy in non-small cell lung cancer-is it becoming a reality?
    • Janku F, Stewart DJ, Kurzrock R,. Targeted therapy in non-small cell lung cancer-is it becoming a reality? Nat Rev Clin Oncol. 2010; 7: 401-414.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 401-414
    • Janku, F.1    Stewart, D.J.2    Kurzrock, R.3
  • 2
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M,. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer. 2008; 8: 915-928.
    • (2008) Nat Rev Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 3
    • 38849088141 scopus 로고    scopus 로고
    • The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer
    • Ryan PD, Goss PE,. The emerging role of the insulin-like growth factor pathway as a therapeutic target in cancer. Oncologist. 2008; 13: 16-24.
    • (2008) Oncologist , vol.13 , pp. 16-24
    • Ryan, P.D.1    Goss, P.E.2
  • 4
    • 70349462997 scopus 로고    scopus 로고
    • The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancers
    • Camidge DR, Dziadziuszko R, Hirsch FR,. The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancers. Clin Lung Cancer. 2009; 10: 262-272.
    • (2009) Clin Lung Cancer , vol.10 , pp. 262-272
    • Camidge, D.R.1    Dziadziuszko, R.2    Hirsch, F.R.3
  • 5
    • 47349101284 scopus 로고    scopus 로고
    • The role of insulin receptors and IGF-I receptors in cancer and other diseases
    • Frasca F, Pandini G, Sciacca L, et al. The role of insulin receptors and IGF-I receptors in cancer and other diseases. Arch Physiol Biochem. 2008; 114: 23-37.
    • (2008) Arch Physiol Biochem , vol.114 , pp. 23-37
    • Frasca, F.1    Pandini, G.2    Sciacca, L.3
  • 6
    • 0346095210 scopus 로고    scopus 로고
    • The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: A review
    • Denley A, Wallace JC, Cosgrove LJ, Forbes BE,. The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review. Horm Metab Res. 2003; 35: 778-785.
    • (2003) Horm Metab Res , vol.35 , pp. 778-785
    • Denley, A.1    Wallace, J.C.2    Cosgrove, L.J.3    Forbes, B.E.4
  • 8
    • 57749089652 scopus 로고    scopus 로고
    • Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
    • Law JH, Habibi G, Hu K, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res. 2008; 68: 10238-10246.
    • (2008) Cancer Res , vol.68 , pp. 10238-10246
    • Law, J.H.1    Habibi, G.2    Hu, K.3
  • 9
    • 70349684824 scopus 로고    scopus 로고
    • Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation
    • Novosyadlyy R, Vijayakumar A, Lann D, Fierz Y, Kurshan N, LeRoith D,. Physical and functional interaction between polyoma virus middle T antigen and insulin and IGF-I receptors is required for oncogene activation and tumour initiation. Oncogene. 2009; 28: 3477-3486.
    • (2009) Oncogene , vol.28 , pp. 3477-3486
    • Novosyadlyy, R.1    Vijayakumar, A.2    Lann, D.3    Fierz, Y.4    Kurshan, N.5    Leroith, D.6
  • 10
    • 70849120946 scopus 로고    scopus 로고
    • Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease
    • Belfiore A, Frasca F, Pandini G, Sciacca L, Vigneri R,. Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease. Endocr Rev. 2009; 30: 586-623.
    • (2009) Endocr Rev , vol.30 , pp. 586-623
    • Belfiore, A.1    Frasca, F.2    Pandini, G.3    Sciacca, L.4    Vigneri, R.5
  • 11
    • 54349083481 scopus 로고    scopus 로고
    • Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer- specific mortality in men with prostate cancer: A long-term survival analysis
    • Ma J, Li H, Giovannucci E, et al. Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer- specific mortality in men with prostate cancer: a long-term survival analysis. Lancet Oncol. 2008; 9: 1039-1047.
    • (2008) Lancet Oncol , vol.9 , pp. 1039-1047
    • Ma, J.1    Li, H.2    Giovannucci, E.3
  • 12
    • 77949579434 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients
    • Cappuzzo F, Tallini G, Finocchiaro G, et al. Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients. Ann Oncol. 2010; 21: 562-527.
    • (2010) Ann Oncol , vol.21 , pp. 562-527
    • Cappuzzo, F.1    Tallini, G.2    Finocchiaro, G.3
  • 13
    • 70350218696 scopus 로고    scopus 로고
    • High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)
    • Gong Y, Yao E, Shen R, et al. High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507). PLoS One. 2009; 4: e7273.
    • (2009) PLoS One , vol.4
    • Gong, Y.1    Yao, E.2    Shen, R.3
  • 14
    • 77952309862 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: A comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression
    • Dziadziuszko R, Merrick DT, Witta SE, et al. Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: a comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression. J Clin Oncol. 2010; 28: 2174-2180.
    • (2010) J Clin Oncol , vol.28 , pp. 2174-2180
    • Dziadziuszko, R.1    Merrick, D.T.2    Witta, S.E.3
  • 15
    • 70450199463 scopus 로고    scopus 로고
    • Prognostic role of insulin- like growth factor receptor-1 expression in small cell lung cancer
    • Chang MH, Lee J, Han J, et al. Prognostic role of insulin- like growth factor receptor-1 expression in small cell lung cancer. APMIS. 2009; 117: 861-869.
    • (2009) APMIS , vol.117 , pp. 861-869
    • Chang, M.H.1    Lee, J.2    Han, J.3
  • 17
    • 77949263123 scopus 로고    scopus 로고
    • Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancer
    • Kim SJ, Rabbani ZN, Dong F, et al. Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancer. Med Oncol. 2010; 27: 91-97.
    • (2010) Med Oncol , vol.27 , pp. 91-97
    • Kim, S.J.1    Rabbani, Z.N.2    Dong, F.3
  • 18
    • 77949360656 scopus 로고    scopus 로고
    • Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung
    • Yuan P, Kadara H, Behrens C, et al. Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. PLoS One. 2010; 5: e9112.
    • (2010) PLoS One , vol.5
    • Yuan, P.1    Kadara, H.2    Behrens, C.3
  • 20
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature. 2006; 439: 353-357.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3
  • 21
    • 58149343905 scopus 로고    scopus 로고
    • Prediction of recurrence- free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression
    • Lee ES, Son DS, Kim SH, et al. Prediction of recurrence- free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression. Clin Cancer Res. 2008; 14: 7397-7404.
    • (2008) Clin Cancer Res , vol.14 , pp. 7397-7404
    • Lee, E.S.1    Son, D.S.2    Kim, S.H.3
  • 22
    • 77951879658 scopus 로고    scopus 로고
    • Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation
    • Zhang H, Fagan DH, Zeng X, Freeman KT, Sachdev D, Yee D,. Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation. Oncogene. 2010; 29: 2517-2527.
    • (2010) Oncogene , vol.29 , pp. 2517-2527
    • Zhang, H.1    Fagan, D.H.2    Zeng, X.3    Freeman, K.T.4    Sachdev, D.5    Yee, D.6
  • 23
    • 58149339692 scopus 로고    scopus 로고
    • Insulin receptor expression by human prostate cancers
    • Cox ME, Gleave ME, Zakikhani M, et al. Insulin receptor expression by human prostate cancers. Prostate. 2009; 69: 33-40.
    • (2009) Prostate , vol.69 , pp. 33-40
    • Cox, M.E.1    Gleave, M.E.2    Zakikhani, M.3
  • 24
    • 65549161522 scopus 로고    scopus 로고
    • Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma
    • Avnet S, Sciacca L, Salerno M, et al. Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma. Cancer Res. 2009; 69: 2443-2452.
    • (2009) Cancer Res , vol.69 , pp. 2443-2452
    • Avnet, S.1    Sciacca, L.2    Salerno, M.3
  • 25
    • 79551562754 scopus 로고    scopus 로고
    • Comprehensive analysis of expression patterns of insulin-like growth factor and Src pathway in patients with non-small cell lung cancer: Two large, independent series of tissue microarray
    • (abstr 10531).
    • Kim J, Kim ES, Liu D, et al. Comprehensive analysis of expression patterns of insulin-like growth factor and Src pathway in patients with non-small cell lung cancer: two large, independent series of tissue microarray. J Clin Oncol. 2010; 28: 15s (abstr 10531).
    • (2010) J Clin Oncol , vol.28
    • Kim, J.1    Kim, E.S.2    Liu, D.3
  • 26
    • 77956665243 scopus 로고    scopus 로고
    • Molecular analysis of non-small cell lung cancer (NSCLC) identifies subsets with different sensitivity to insulin like growth factor i receptor (IGF-IR) inhibition
    • Gualberto A, Dolled-Filhart M, Gustavson M, et al. Molecular analysis of non-small cell lung cancer (NSCLC) identifies subsets with different sensitivity to insulin like growth factor I receptor (IGF-IR) inhibition. Clin Cancer Res. 2010; 16: 4654-4665.
    • (2010) Clin Cancer Res , vol.16 , pp. 4654-4665
    • Gualberto, A.1    Dolled-Filhart, M.2    Gustavson, M.3
  • 27
    • 33846458639 scopus 로고    scopus 로고
    • Down-regulation of type i insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin
    • Zhang H, Pelzer AM, Kiang DT, Yee D,. Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin. Cancer Res. 2007; 67: 391-397.
    • (2007) Cancer Res , vol.67 , pp. 391-397
    • Zhang, H.1    Pelzer, A.M.2    Kiang, D.T.3    Yee, D.4
  • 28
    • 34548479484 scopus 로고    scopus 로고
    • Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action
    • Fulzele K, DiGirolamo DJ, Liu Z, Xu J, Messina JL, Clemens TL,. Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action. J Biol Chem. 2007; 282: 25649-25658.
    • (2007) J Biol Chem , vol.282 , pp. 25649-25658
    • Fulzele, K.1    Digirolamo, D.J.2    Liu, Z.3    Xu, J.4    Messina, J.L.5    Clemens, T.L.6
  • 29
    • 77953973648 scopus 로고    scopus 로고
    • Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy
    • Ulanet DB, Ludwig DL, Kahn CR, Hanahan D,. Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci USA. 2010; 107: 10791-10798.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10791-10798
    • Ulanet, D.B.1    Ludwig, D.L.2    Kahn, C.R.3    Hanahan, D.4
  • 30
    • 66349091290 scopus 로고    scopus 로고
    • Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer
    • Karp DD, Paz-Ares LG, Novello S, et al. Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer. J Clin Oncol. 2009; 27: 2516-2522.
    • (2009) J Clin Oncol , vol.27 , pp. 2516-2522
    • Karp, D.D.1    Paz-Ares, L.G.2    Novello, S.3
  • 31
    • 31544464616 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417
    • Haluska P, Carboni JM, Loegering DA, et al. In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417. Cancer Res, 2006; 66: 362-371.
    • (2006) Cancer Res , vol.66 , pp. 362-371
    • Haluska, P.1    Carboni, J.M.2    Loegering, D.A.3
  • 32
    • 77958067823 scopus 로고    scopus 로고
    • Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): Rationale for cotargeting IGF-1R and IR in cancer
    • Buck E, Gokhale PC, Koujak S, et al. Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer. Mol Cancer Ther. 2010; 9: 2652-2664.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2652-2664
    • Buck, E.1    Gokhale, P.C.2    Koujak, S.3
  • 33
    • 65649122657 scopus 로고    scopus 로고
    • Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinase
    • Sabbatini P, Rowand JL, Groy A, et al. Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinase. Clin Cancer Res. 2009; 15: 3058-3067.
    • (2009) Clin Cancer Res , vol.15 , pp. 3058-3067
    • Sabbatini, P.1    Rowand, J.L.2    Groy, A.3
  • 34
    • 70350214534 scopus 로고    scopus 로고
    • Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: Effect of the dual-receptor inhibitor BMS-536924 in vitro
    • Wahner Hendrickson AE, Haluska P, Schneider PA, et al. Expression of insulin receptor isoform A and insulin-like growth factor-1 receptor in human acute myelogenous leukemia: effect of the dual-receptor inhibitor BMS-536924 in vitro. Cancer Res. 2009; 69: 7635-7643.
    • (2009) Cancer Res , vol.69 , pp. 7635-7643
    • Wahner Hendrickson, A.E.1    Haluska, P.2    Schneider, P.A.3
  • 35
    • 70349982602 scopus 로고    scopus 로고
    • Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: Implications for cellular potency and selectivity over insulin receptor
    • Wood ER, Shewchuk L, Hassel A, et al. Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor. Biochem Pharmacol. 2009; 78: 1438-1447.
    • (2009) Biochem Pharmacol , vol.78 , pp. 1438-1447
    • Wood, E.R.1    Shewchuk, L.2    Hassel, A.3
  • 36
    • 58149107984 scopus 로고    scopus 로고
    • The insulin-like growth factor pathway in lung cancer
    • Dziadziuszko R, Camidge DR, Hirsch FR,. The insulin-like growth factor pathway in lung cancer. J Thorac Oncol. 2008; 3: 815-818.
    • (2008) J Thorac Oncol , vol.3 , pp. 815-818
    • Dziadziuszko, R.1    Camidge, D.R.2    Hirsch, F.R.3
  • 37
    • 77951460650 scopus 로고    scopus 로고
    • The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non- small cell lung cancer
    • Gridelli C, Rossi A, Bareschino MA, Schettino C, Sacco PC, Maione P,. The potential role of insulin-like growth factor receptor inhibitors in the treatment of advanced non- small cell lung cancer. Expert Opin Investig Drugs. 2010; 19: 631-639.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 631-639
    • Gridelli, C.1    Rossi, A.2    Bareschino, M.A.3    Schettino, C.4    Sacco, P.C.5    Maione, P.6
  • 38
    • 70449699792 scopus 로고    scopus 로고
    • Intracellular presence of insulin and its phosphorylated receptor in non- small cell lung cancer
    • Mattarocci S, Abbruzzese C, Mileo AM, et al. Intracellular presence of insulin and its phosphorylated receptor in non- small cell lung cancer. J Cell Physiol. 2009; 221: 766-770.
    • (2009) J Cell Physiol , vol.221 , pp. 766-770
    • Mattarocci, S.1    Abbruzzese, C.2    Mileo, A.M.3


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