Live Attenuated Influenza Virus (LAIV) induces different mucosal T cell function in nonsmokers and smokers

Clinical Immunology

Volumn 142, Issue 3, 2012, Pages 232-236

  Horvath, Katherine M ^a   Brighton, Luisa E ^b   Herbst, Margaret ^b   Noah, Terry L ^b   Jaspers, Ilona ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Cigarette smoke; Gamma delta t cells; Influenza; Nasal mucosa

Indexed keywords

CD45 ANTIGEN; INFLUENZA VACCINE; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOCOMPETENT CELL; INOCULATION; LONGITUDINAL STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MALE; MUCOSA CELL; NASAL BIOPSY; NOSE MUCOSA; PRIORITY JOURNAL; PROSPECTIVE STUDY; SMOKING; T LYMPHOCYTE ACTIVATION; TURBINATE;

ADOLESCENT; ADULT; BIOPSY; CELL SURVIVAL; FEMALE; HUMANS; IMMUNITY, MUCOSAL; INFLUENZA VACCINES; MALE; PROSPECTIVE STUDIES; SMOKING; T-LYMPHOCYTES; VACCINES, ATTENUATED; YOUNG ADULT;

EID: 84857373582     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2011.12.013     Document Type: Article

References (23)

1. Horvath K.M., Brighton L.E., Zhang W., Carson J.L., Jaspers I. Epithelial cells from smokers modify dendritic cell responses in the context of influenza infection. Am. J. Respir. Cell Mol. Biol. 2011, 45:237-245.
2. Jaspers I., Horvath K.M., Zhang W., Brighton L.E., Carson J.L., Noah T.L. Reduced expression of IRF7 in nasal epithelial cells from smokers after infection with influenza. Am. J. Respir. Cell Mol. Biol. 2010, 43:368-375.
3. Noah T.L., Zhou H., Monaco J., Horvath K., Herbst M., Jaspers I. Tobacco smoke exposure and altered nasal responses to live attenuated influenza virus. Environ. Health Perspect. 2011, 119:78-83.
4. MacKenzie J.S., MacKenzie I.H., Holt P.G. The effect of cigarette smoking on susceptibility to epidemic influenza and on serological responses to live attenuated and killed subunit influenza vaccines. J. Hyg. (Lond) 1976, 77:409-417.
5. Pyhala R., Takala J., Turunen A., Aho K. Smoking and influenza in the elderly: a sero-epidemiological study. Eur. J. Respir. Dis. 1983, 64:212-216.
6. Mancini D.A., Mendonca R.M., Mendonca R.Z., do Prado J.A., Andrade Cde M. Immune response to vaccine against influenza in smokers, non-smokers and, in individuals holding respiratory complications. Boll. Chim. Farm. 1998, 137:21-25.
7. Boyce T.G., Gruber W.C., Coleman-Dockery S.D., Sannella E.C., Reed G.W., Wolff M., Wright P.F. Mucosal immune response to trivalent live attenuated intranasal influenza vaccine in children. Vaccine 1999, 18:82-88.
8. Maassab H.F., Bryant M.L. The development of live attenuated cold-adapted influenza virus vaccine for humans. Rev. Med. Virol. 1999, 9:237-244.
9. Hammitt L.L., Bartlett J.P., Li S., Rahkola J., Lang N., Janoff E.N., Levin M.J., Weinberg A. Kinetics of viral shedding and immune responses in adults following administration of cold-adapted influenza vaccine. Vaccine 2009, 27:7359-7366.
10. Lau Y.F., Santos C., Torres-Velez F.J., Subbarao K. The magnitude of local immunity in the lungs of mice induced by live attenuated influenza vaccines is determined by local viral replication and induction of cytokines. J. Virol. 2011, 85:76-85.
11. Wisnewski A.V., Cain H., Magoski N., Wang H., Holm C.T., Redlich C.A. Human gamma/delta T-cell lines derived from airway biopsies. Am. J. Respir. Cell Mol. Biol. 2001, 24:332-338.
12. Steinle A., Li P., Morris D.L., Groh V., Lanier L.L., Strong R.K., Spies T. Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics 2001, 53:279-287.
13. Bonneville M., O'Brien R.L., Born W.K. Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 2010, 10:467-478.
14. Carding S.R. A role for gamma/delta T cells in the primary immune response to influenza virus. Res. Immunol. 1990, 141:603-606.
15. Eichelberger M., Allan W., Carding S.R., Bottomly K., Doherty P.C. Activation status of the CD4-8- gamma delta-T cells recovered from mice with influenza pneumonia. J. Immunol. 1991, 147:2069-2074.
16. Horvath K.M., Herbst M., Zhou H., Zhang H., Noah T.L., Jaspers I. Nasal lavage natural killer cell function is suppressed in smokers after live attenuated influenza virus. Respir. Res. 2011, 12:102.
17. Jahnsen F.L., Farstad I.N., Aanesen J.P., Brandtzaeg P. Phenotypic distribution of T cells in human nasal mucosa differs from that in the gut. Am. J. Respir. Cell Mol. Biol. 1998, 18:392-401.
18. Verbist K.C., Cole C.J., Field M.B., Klonowski K.D. A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection. J. Immunol. 2011, 186:174-182.
19. Roos-Engstrand E., Pourazar J., Behndig A.F., Blomberg A., Bucht A. Cytotoxic T cells expressing the co-stimulatory receptor NKG2 D are increased in cigarette smoking and COPD. Respir. Res. 2010, 11:128.
20. Olloquequi J., Ferrer J., Montes J.F., Rodriguez E., Montero M.A., Garcia-Valero J. Differential lymphocyte infiltration in small airways and lung parenchyma in COPD patients. Respir. Med. 2010, 104:1310-1318.
21. Bouloukaki I., Tsoumakidou M., Vardavas C.I., Mitrouska I., Koutala E., Siafakas N.M., Schiza S.E., Tzanakis N. Maintained smoking cessation for 6 months equilibrates the percentage of sputum CD8+ lymphocyte cells with that of nonsmokers. Mediators Inflamm. 2009, 2009:812102.
22. Roos-Engstrand E., Ekstrand-Hammarstrom B., Pourazar J., Behndig A.F., Bucht A., Blomberg A. Influence of smoking cessation on airway T lymphocyte subsets in COPD. COPD 2009, 6:112-120.
23. Roos-Engstrand E., Pourazar J., Behndig A.F., Bucht A., Blomberg A. Expansion of CD4+CD25+ helper T cells without regulatory function in smoking and COPD. Respir. Res. 2011, 12:74.