Effects of subtherapeutic concentrations of chlorhexidine gluconate on germ tube formation of oral Candida

Medical Principles and Practice

Volumn 21, Issue 2, 2012, Pages 120-124

  Ellepola, Arjuna N B ^a   Joseph, Bobby J ^a   Khan, Z U ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Candida albicans; Chlorhexidine gluconate; Germ tubes

Indexed keywords

CHLORHEXIDINE GLUCONATE;

ARTICLE; CANDIDA ALBICANS; CELL WALL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; FUNGAL CELL; FUNGUS ISOLATION; NONHUMAN; THRUSH;

ANTI-INFECTIVE AGENTS, LOCAL; ASTHMA; CANDIDA ALBICANS; CANDIDIASIS, ORAL; CHLORHEXIDINE; DIABETES COMPLICATIONS; HUMANS; MOUTHWASHES; SMOKING;

EID: 84857371373     PISSN: 10117571     EISSN: 14230151     Source Type: Journal    
DOI: 10.1159/000332569     Document Type: Article

References (24)

1. Ellepola AN, Samaranayake LP: Antimycotic agents in oral candidosis: An overview: 1. Clinical variants. Dent Update 2000; 27: 111-112, 114-116.
2. Waltimo TM, Sirén EK, Torkko HL, Olsen I, Haapasalo MP: Fungi in therapy-resistant apical periodontitis. Int Endod J 1997; 30: 96-101. (Pubitemid 127490908)
3. Sen BH, Safavi KE, Spangberg LS: Colonization of Candida albicans on cleaned human dental hard tissues. Arch Oral Biol 1997; 42: 513-520. (Pubitemid 27382423)
4. Shepherd MG: Biology of Candida species; in Samaranayake LP, MacFarlane TW (eds): Oral Candidosis. London, Wright, Butterworth, 1990, pp 10-20.
5. Richardson MD, Smith H: Production of germ tubes by virulent and attenuated strains of Candida albicans J Infect Dis 1981; 144: 565-569. (Pubitemid 12194461)
6. Tronchin G, Bouchara JP, Robert R, Senet JM: Adherence of Candida albicans germ tubes to plastic: Ultrastructural and molecular studies of fibrillar adhesins. Infect Immun 1988; 56: 1987-1993.
7. Sobel JD, Muller G, Buckley HR: Critical role of germ tube formation in the pathogenesis of candidal vaginitis. Infect Immun 1984; 44: 576-580. (Pubitemid 14112683)
8. MacNeill S, Rindler E, Walker A, Brown AR, Cobb CM: Effects of tetracycline hydrochloride and chlorhexidine gluconate on Candida albicans An in vitro study. J Clin Periodontol 1997; 24: 753-760. (Pubitemid 127731621)
9. Budtz-Jorgensen E: Candida -associated denture stomatitis and angular chelitis; in Samaranayake LP, MacFarlane TW (eds): Oral Candidosis. London, Wright, Butterworth, 1990, pp 156-183.
10. Tobgi RS, Samaranayake LP, Macfarlane TW: Adhesion of Candida albicans to buccal epithelial cells exposed to chlorhexidine gluconate. J Med Vet Mycol 1987; 25: 335-338. (Pubitemid 18082799)
11. Darwazeh AM, Lamey PJ, MacFarlane TW, McCuish AC: The effect of exposure to chlorhexidine gluconate in vitro and in vivo on in vitro adhesion of Candida albicans to buccal epithelial cells from diabetic and nondiabetic subjects. J Oral Pathol Med 1994; 23: 130-132.
12. McCourtie J, MacFarlane TW, Samaranayake LP: A comparison of the effects of chlorhexidine gluconate, amphotericin B and nystatin on the adherence of Candida species to denture acrylic. J Antimicrob Chemother 1986; 17: 575-583. (Pubitemid 16114801)
13. Anil S, Ellepola AN, Samaranayake LP: The impact of chlorhexidine gluconate on the relative cell surface hydrophobicity of oral Candida albicans Oral Dis 2001; 7: 119-122. (Pubitemid 32318829)
14. Pusateri CR, Monaco EA, Edgerton M: Sensitivity of Candida albicans biofilm cells grown on denture acrylic to antifungal proteins and chlorhexidine. Arch Oral Biol 2009; 54: 588-594.
15. Ellepola AN, Samaranayake LP: Adjunctive use of chlorhexidine in oral candidoses: A review. Oral Dis 2001; 7: 11-17. (Pubitemid 32216851)
16. Bonesvoll P, Lökken P, Rölla G, Paus PN: Retention of chlorhexidine in the human oral cavity after mouth rinses. Arch Oral Biol 1974; 19: 209-212.
17. Ellepola AN, Samaranayake LP: The effect of brief exposure to sub-therapeutic concentrations of chlorhexidine gluconate on the germ tube formation of oral Candida albicans and its relationship to post-antifungal effect. Oral Dis 2000; 6: 166-171. (Pubitemid 30340643)
18. Ellepola AN, Samaranayake LP: Inhalation and topical steroids, and oral candidosis: A mini review. Oral Dis 2001; 7: 211-216. (Pubitemid 32734918)
19. Soysa NS, Ellepola AN: The impact of cigarette/ tobacco smoking on oral candidosis: An overview. Oral Dis 2005; 11: 268-273. (Pubitemid 41725936)
20. Soysa NS, Samaranayake LP, Ellepola AN: Diabetes mellitus as a contributory factor in oral candidosis. Diab Med 2005; 23: 455-459.
21. Craig WA, Gudmundsson S: The postantibiotic effect; in Lorian V (ed): Antibiotics in Laboratory Medicine. Baltimore, Williams & Wilkins, 1996, pp 296-329.
22. Brayman TG, Wilks JW: Sensitive assay for antifungal activity of glucan synthase inhibitors that uses germ tube formation in Candida albicans as an end point. Antimicrob Agents Chemother 2003; 47: 3305-3310. (Pubitemid 37229593)
23. Bobichon H, Bouchet P: Action of chlorhexidine on budding Candida albicans : Scanning and transmission electron microscopic study. Mycopathologia 1987; 100: 27-35.
24. Cassone A, Simonetti N, Strippoli V: Ultrastructural changes in the wall during germtube formation from blastospores of Candida albicans J Gen Microbiol 1973; 77: 417-426.