The novel compound OSI-461 induces apoptosis and growth arrest in human acute myeloid leukemia cells

Annals of Hematology

Volumn 91, Issue 2, 2012, Pages 173-181

  Singh, Raminder ^a   Fröbel, Julia ^a   Cadeddu, Ron Patrick ^a   Bruns, Ingmar ^a   Schroeder, Thomas ^a   Brünnert, Daniela ^a   Wilk, Christian Matthias ^a   Zerbini, Luiz Fernando ^b   Haas, Rainer ^a   Czibere, Akos ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

AML; Apoptosis; GADD45; Growth arrest; OSI 461

Indexed keywords

ANTINEOPLASTIC AGENT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 ALPHA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 GAMMA; INTERLEUKIN 24; OSI 461; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL METABOLISM; CELL PROLIFERATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; TARGET CELL; TREATMENT DURATION;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CLINICAL TRIALS AS TOPIC; GENE EXPRESSION; HUMANS; LEUKEMIA, MYELOID, ACUTE; PHOSPHODIESTERASE INHIBITORS; SULINDAC;

EID: 84857364177     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1282-4     Document Type: Article

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