In vitro antiplasmodial activity and cytotoxicity of extracts and fractions of Vitex madiensis, medicinal plant of Gabon

Tropical Medicine and International Health

Volumn 17, Issue 3, 2012, Pages 316-321

  Ondo, J P ^a,b,c   Lekana Douki, J B ^b   Bongui, J B ^c   Zang Edou, E S ^b   Zatra, R ^b   Toure Ndouo, F S ^b   Elomri, A ^a   Lebibi, J ^c   Seguin, E ^a  

^a UNIVERSITÉ DE ROUEN   (France)

^b Institut de Recherches pour le Développement U034   (Gabon)

^c UNIVERSITÉ DES SCIENCES ET TECHNIQUES DE MASUKU   (Gabon)

Author keywords

Antiplasmodial activity; Cytotoxicity; Field isolates; Gabon pharmacopeia; Plasmodium falciparum; Vitex madiensis

Indexed keywords

ANTIMALARIAL AGENT; BUTANOL; CHLOROQUINE; CYCLOHEXANE; DICHLOROMETHANE; PLANT EXTRACT; TETRAZOLIUM; UNCLASSIFIED DRUG; VITEX MADIENSIS EXTRACT;

BIOASSAY; CYTOLOGY; DISEASE CONTROL; LEAF; MALARIA; MEDICINAL PLANT; PLANT EXTRACT; SYMPTOM; TOXICITY;

ANTIMALARIAL ACTIVITY; ARTICLE; BARK; CANCER CELL; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG SELECTIVITY; GABON; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEDICINAL PLANT; NONHUMAN; PARASITE ISOLATION; PLANT LEAF; PLANT STEM; PLASMODIUM FALCIPARUM; VITEX MADIENSIS;

ANTIMALARIALS; CELL LINE; GABON; HUMANS; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; PLASMODIUM FALCIPARUM; VITEX;

GABON; HAUT OGOOUE;

LAMIACEAE; PLASMODIUM FALCIPARUM; VITEX;

EID: 84857364031     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2011.02922.x     Document Type: Article

References (20)

1. Benoit-Vical F, Valentin A, Cournac V, Pélissier Y, Mallié M & Bastide JM (1998) In vitro antiplasmodial activity of stem and root extracts of Nauclea latifolia S M. (Rubiaceae). Journal of Ethnopharmacology 61, 173-178.
2. Bossard E (1996) La médecine traditionnelle au Centre et à l'Ouest de l'Angola. Ministério da ciênciae eda tecnologia. Instituto de Investigaçâo Cientifica Tropical, Lisboa.
3. Breman JG (2001) The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. American Journal of Tropical Medicine and Hygiene 64, 1-11.
4. Darwish FMM & Reinecke MG (2003) Ecdysteroids and other constituents from Sida spinosa L. Phytochemistry 62, 1179-1184.
5. Druilhe P, Moreno A, Blanc C, Brasseur PH & Jacquier P (2001) A colorimetric in vitro drug sensitivity assay for Plasmodium falciparum based on a highly sensitive double-site lactate dehydrogenase antigen-capture enzyme-linked immunosorbent assay. American Journal of Tropical Medicine and Hygiene 64, 233-241.
6. Fernandes R (2005) Lamiaceae (subfamilies: Viticoideae and Ajugoideae). FZ volume: 8 parts: 7. (Accessed 22 October 2008).
7. Haxaire C(1979) Phytothérapie et médecine familiale chez les Gbaya-kara (République Centrafricaine). Dissertation, Université de Paris 5.
8. Kaddouri H, Nakache S, Houzé S, Mentré F & Le Bras J (2006) Assessment of the drug susceptibility of Plasmodium falciparum clinical isolates from Africa by using a Plasmodium lactate dehydrogenase immunodetection assay and an inhibitory maximum effect model for precise measurement of the 50-percent inhibitory concentration. Antimicrobial Agents and Chemotherapy 50, 3343-3349.
9. Kaur K, Jain M, Kaur T & Jain R (2009) Antimalarials from nature. Bioorganic & Medicinal Chemistry 17, 3229-3256.
10. Kubo I, Matsumoto A & Ayafor JF (1984) Efficient isolation of a large amount of 20-Hydroxyecdysone from Vitex madiensis (Verbenaceae) by droplet counter-current chromatography. Agricultural Biology and Chemistry 48, 1683-1684.
11. Lekana-Douki JB, Sterkers Y, Lépolard C et al. (2003) Adhesion of normal and Plasmodium falciparum ring-infected erythrocytes to endothelial cells and the placenta involves the rhoptry-derived ring surface protein-2. Blood 101, 5025-5032.
12. Lekana-Douki JB, Bongui JB, Oyegue Liabagui SL et al. (2011) In vitro antiplasmodial activity and cytotoxicity of nine plants traditionally used in Gabon. Journal of Ethnopharmacology 133, 1103-1108.
13. Malgras D (1992) Arbres et arbustes guérisseurs des savanes maliennes Karthala, Paris.
14. Mapongmetsem PM (2006) Domestication of Vitex madiensis in the Adamawa highlands of Cameroon: phenology and propagation. Akdeniz Universitesi Ziraat Fakultesi Dergisi 19, 269-278.
15. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65, 55-63.
16. Nyiligira E, Viljoen AM, Van Heerden FR, Van Zyl RL, Van Vuuren SF & Steenkamp PA (2008) Phytochemistry and in vitro pharmacological activities of South African Vitex (Verbenaceae) species. Journal of Ethnopharmacology 119, 680-685.
17. Phillipson JD & Wright CW (1991) Can ethnopharmacology contribute to the development of antimalarial agents? Journal of Ethnopharmacology 32, 155-165.
18. Planche T, Krishna S, Kombila M et al. (2001) Comparison of methods for the rapid laboratory assessment of children with malaria. American Journal of Tropical Medicine and Hygiene 65, 599-602.
19. Udeinya IJ (1993) Anti-malarial activity of Nigerian neem leaves. Transactions of the Royal Society of Tropical Medicine and Hygiene 87, 471.
20. World Health Organization. (2010) World malaria report 2010.