A note on the robustness of the continual reassessment method

Statistics and Probability Letters

Volumn 82, Issue 5, 2012, Pages 902-906

  Azriel, David ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Consistency; Continual reassessment method; Misspecified model; Phase I trials

Indexed keywords

EID: 84857254452     PISSN: 01677152     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spl.2012.01.026     Document Type: Article

References (5)

1. Azriel D., Mandel M., Rinott Y. The treatment versus experimentation dilemma in dose-finding studies. Journal of Statistical Planning and Inference 2011, 141:2759-2768.
2. Cheung Y.K., Chappell R. A simple technique to evaluate model sensitivity in the continual reassessment method. Biometrics 2002, 58:671-674.
3. O'Quigley J., Pepe M., Fisher L. Continual reassessment method: a practical design for phase 1 clinical trials in cancer. Biometrics 1990, 46:33-48.
4. Oron A., Azriel D., Hoff P. Dose-finding designs: the role of convergence properties. The International Journal of Biostatistics 2011, 7. Article 39.
5. Shen L.Z., O'Quigley J. Consistency of continual reassessment method under model misspecification. Biometrika 1996, 83:395-405.