Levamisole-adulterated in cocaine causing agranulocytosis, vasculopathy, and acquired protein S deficiency

Annals of Hematology

Volumn 91, Issue 3, 2012, Pages 477-478

  Dy, Irene ^a   Pokuri, Venkata ^a   Olichney, John ^a   Wiernik, Peter ^a  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; COCAINE; HEMOGLOBIN; LEVAMISOLE; MYELOBLASTIN; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; PREDNISONE; PROTEIN S; RHEUMATOID FACTOR;

ADULT; AGRANULOCYTOSIS; ANEMIA; ARTHRALGIA; BLOOD ANALYSIS; CASE REPORT; COCAINE DEPENDENCE; FEMALE; FEVER; HUMAN; LABORATORY TEST; LETTER; NEUTROPENIA; PRIORITY JOURNAL; PROTEIN S DEFICIENCY; PURPURA; SKIN DEFECT; THROMBOCYTE COUNT; TREATMENT OUTCOME; URINALYSIS; VASCULAR DISEASE;

ADULT; AGRANULOCYTOSIS; COCAINE; COCAINE-RELATED DISORDERS; DRUG CONTAMINATION; FEMALE; HUMANS; LEVAMISOLE; PROTEIN S DEFICIENCY;

EID: 84857242899     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1294-0     Document Type: Letter

References (11)

1. N Scheinfeld JD Rosenberg JM Weinberg 2004 Levamisole in dermatology: a review Am J Clin Dermatol 5 2 97 104 15109274 10.2165/00128071-200405020-00004 (Pubitemid 38626392)
2. DR Czuchlewski, et al. 2010 Clinicopathologic features of agranulocytosis in the setting of levamisole-tainted cocaine Am J Clin Pathol 133 466 472 20154286 10.1309/AJCPOPQNBP5THKP1
3. NMG Walsh, et al. 2010 Cocaine-related retiform purpura: evidence to incriminate the adulterant, levamisole J Cutan Pathol 37 1212 1219 20738457 10.1111/j.1600-0560.2010.01613.x
4. A Chang J Osterloh J Thomas 2010 Levamisole: a dangerous new cocaine adulterant Nature 88 3 408 411 1:STN:280:DC%2BC3cjmtFWrtQ%3D%3D
5. NY Zhu DF LeGatt AR Turner 2009 Agranulocytosis after consumption of cocaine adulterated with levamisole Ann Intern Med 150 281 289
6. M Bradford, et al. 2010 Bilateral necrosis of earlobes and cheeks: another complication of cocaine contaminated with levamisole Ann Intern Med 152 758 759 20513844
7. JM Waller, et al. 2010 Cocaine-associated retiform purpura and neutropenia: is levamisole the culprit? J Am Acad Dermatol 63 530 535 20304523 10.1016/j.jaad.2010.01.055
8. MO Wiens, et al. 2010 Cocaine adulterant linked to neutropenia CMAJ 182 1 57 19969562 10.1503/cmaj.090286
9. JA Buchanan, et al. 2010 A confirmed case of agranulocytosis after use of cocaine contaminated with levamisole J Med Toxicol 6 160 164 20358411 10.1007/s13181-010-0060-3
10. M Brackney, et al. 2009 Agranulocytosis associated with cocaine use-four states, March 2008-November 2009 MMWR 58 49 1381 1385
11. KS Song YS Park HK Kim 2000 Prevalence of Anti-protein S antibodies in patients with Systemic Lupus Ertyhematosus Arthritis Rheum 43 3 557 560 10728748 10.1002/1529-0131(200003)43:3<557::AID-ANR11>3.0.CO;2-O 1:STN:280:DC%2BD3c7ptFSqsA%3D%3D (Pubitemid 30394946)