Phytochemical investigation and in vitro cytotoxic evaluation of alkaloids from abuta rufescens

Planta Medica

Volumn 78, Issue 3, 2012, Pages 230-232

  Swaffar, Diane S ^a   Holley, Chad J ^a   Fitch, Richard W ^b   Elkin, Kyle R ^c   Zhang, Clarice ^c   Sturgill, Jennifer P ^c   Menachery, Mary D ^c  

^a ROSEMAN UNIVERSITY OF HEALTH SCIENCES   (United States)

^b INDIANA STATE UNIVERSITY   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Abuta rufescens Abuta splendida; azafluoranthenes; cytotoxicity; Menispermaceae; oxoaporphines; tropoloisoquinolines

Indexed keywords

ALKALOID; CAMPTOTHECIN; DOXORUBICIN; ETOPOSIDE; GRANDIRUBRINE; HOMOMOSCHATOLINE; IMELUTEINE; IMENINE; IMERUBRINE; ISOIMERUBRINE; ISOIMIRUBRINE; LYSICAMINE; NORRUFESCINE; SPLENDIDINE; SUBSESSILINE; TELITOXINE; UNCLASSIFIED DRUG; VINBLASTINE;

ABUTA RUFESCENS; ARTICLE; CANCER CELL CULTURE; COLON ADENOCARCINOMA; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CARCINOMA; LUNG CARCINOMA; MEDICINAL PLANT; PHYTOCHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; COLONIC NEOPLASMS; HUMANS; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MENISPERMACEAE; NEOPLASMS, BASAL CELL; PERU; PHYTOTHERAPY; PLANT EXTRACTS;

ABUTA; MENISPERMACEAE;

EID: 84857237486     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280383     Document Type: Article

References (20)

1. Krukoff B A., Barneby R C. Supplementary notes on American menispermaceae: neotropical triclisieae and anospermaceae. Phytologia 1978 39 283-293
2. Menachery M D. The alkaloids of South American menispermaceae. In: Pelletier S W. editor Alkaloids: chemical & biological perspectives. Vol. 11 London Pergamon Press 1996 269-302
3. Cava M P., Buck K T., Noguchi I, Srinivasan M, Rao M G., DaRocha A I. The alkaloids of Abuta imene and Abuta rufescens. Tetrahedron 1975 31 1667-1669
4. Sa J M., Lakshmikantham M V., Mitchell M J., Cava M P. Krukovine, a new bisbenzylisoquinoline alkaloid from Abuta splendida Krukoff and Moldenke. J Org Chem 1976 41 317-319
5. Skiles J W., Sa J M., Cava M P. Splendidine, a new oxoaporphine alkaloid from Abuta rufescens Aublet. Can J Chem 1979 57 1642-1646 (Pubitemid 10220603)
6. Krukoff B A., Moldenke H N. Studies of American Menispermaceae, with special reference to species used in preparation of arrow-poisons. Brittonia 1938 3 50-71
7. Itokawa H, Matsumoto K, Morita H, Takeya K. Preparation and antileukemic activity of congeners of tropoloisoquinoline alkaloids from Abuta concolor. Heterocycles 1994 37 1025-1031
8. Morita H, Matsumoto K, Takeya K, Itokawa H. Azafluoranthene alkaloids from Cissampelos pareira. Chem Pharm Bull 1993 41 1307-1308 (Pubitemid 23279418)
9. Menachery M D., Cava M P. Grandirubrine, a new tropoloisoquinoline alkaloid. Heterocycles 1980 14 943-945
10. Menachery M D., Blake G W., Gourley R C., Freyer A. Telisatin A, telisatin B, and telitoxinone, three new aporphinoids from Telitoxicum peruvianum. J Nat Prod 1995 58 1945-1949 (Pubitemid 26071155)
11. Menachery M D., Cava M P. The alkaloids of Telitoxicum peruvianum. J Nat Prod 1981 44 320-323 (Pubitemid 11063242)
12. Skiles J W., Cava M P. Subsessiline: structure revision and synthesis. J Org Chem 1979 44 409-412 (Pubitemid 9170559)
13. Mossmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983 65 55-63
14. Bane Hastie S, Williams R C., Pruett D, McDonald T L. The binding of isocolchicine to tubulin. J Biol Chem 1989 264 6682-6688
15. Boger D L., Takahashi K. Total synthesis of granditropone, grandirubrine, imerubrine, and isoimerubrine. J Am Chem Soc 1995 117 12452-12459 (Pubitemid 26201336)
16. Banwell M G., Hamel E, Ireland N K., Mackay M F. Regiocontrolled total syntheses of the tropoloisoquinoline alkaloids imerubrine and grandirubrine. Heterocycles 1994 39 205-217
17. Banwell M G., Ireland N K. Regiocontrolled total synthesis of imerubrine: the first total synthesis of a tropoloisoquinoline alkaloid. J Chem Soc Chem Commun 1994 591-592 (Pubitemid 24088710)
18. Lee J C., Cha J K. Total synthesis of tropoloisoquinolines: imerubrine, isoimerubrine, and grandirubrine. J Am Chem Soc 2001 123 3243-3246
19. Chaturvedula V S., Norris A, Miller J S., Ratovoson F, Andriantsiferana R, Rasamison V E., Kingston D G. Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest. J Nat Prod 2006 69 287-289
20. Swaffar D S., Ireland C M., Barrows L R. A rapid mechanism-based screen to detect potential anti-cancer agents. Anticancer Drugs 1994 5 15-23 (Pubitemid 24066557)