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Volumn 36, Issue 4, 2012, Pages 407-412

Are low-intensity induction strategies better for older patients with acute myeloid leukemia?

Author keywords

Acute; Aged; Clinical trials; Drug therapy; Leukemia; Myeloid; Remission induction

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTILEUKEMIC AGENT; ARSENIC TRIOXIDE; CPX 351; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; GEMTUZUMAB; GEMTUZUMAB OZOGAMICIN; HEMOPOIETIC GROWTH FACTOR; KW 2449; LAROMUSTINE; LINTUZUMAB; TIPIFARNIB; UNCLASSIFIED DRUG;

EID: 84857232803     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.12.019     Document Type: Article
Times cited : (8)

References (20)
  • 1
    • 84857237527 scopus 로고    scopus 로고
    • National Cancer Institute. Acute Myeloid Leukemia - Surveillance Epidemiology and End Results Stat Fact Sheets: Acute Myeloid Leukemia. [accessed 15.07.2011].
    • National Cancer Institute. Acute Myeloid Leukemia - Surveillance Epidemiology and End Results Stat Fact Sheets: Acute Myeloid Leukemia. [accessed 15.07.2011]. http://seer.cancer.gov/statfacts/html/amyl.html.
  • 3
    • 33644521267 scopus 로고    scopus 로고
    • Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome
    • Kantarjian H., O'Brien S., Cortes J., Giles F., Faderl S., Jabbour E., et al. Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome. Cancer 2006, 106:1090-1098.
    • (2006) Cancer , vol.106 , pp. 1090-1098
    • Kantarjian, H.1    O'Brien, S.2    Cortes, J.3    Giles, F.4    Faderl, S.5    Jabbour, E.6
  • 4
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications
    • Marcucci G., Haferlach T., Dohner H. Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. J Clin Oncol 2011, 29:475-486.
    • (2011) J Clin Oncol , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Dohner, H.3
  • 5
    • 0024458031 scopus 로고
    • On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: a randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group
    • Lowenberg B., Zittoun R., Kerkhofs H., Jehn U., Abels J., Debusscher L., et al. On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: a randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group. J Clin Oncol 1989, 7:1268-1274.
    • (1989) J Clin Oncol , vol.7 , pp. 1268-1274
    • Lowenberg, B.1    Zittoun, R.2    Kerkhofs, H.3    Jehn, U.4    Abels, J.5    Debusscher, L.6
  • 6
    • 66149148673 scopus 로고    scopus 로고
    • Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry
    • Juliusson G., Antunovic P., Derolf A., Lehmann S., Mollgard L., Stockelberg D., et al. Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry. Blood 2009, 113:4179-4187.
    • (2009) Blood , vol.113 , pp. 4179-4187
    • Juliusson, G.1    Antunovic, P.2    Derolf, A.3    Lehmann, S.4    Mollgard, L.5    Stockelberg, D.6
  • 7
    • 33947205565 scopus 로고    scopus 로고
    • A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment
    • Burnett A.K., Milligan D., Prentice A.G., Goldstone A.H., McMullin M.F., Hills R.K., et al. A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment. Cancer 2007, 109:1114-1124.
    • (2007) Cancer , vol.109 , pp. 1114-1124
    • Burnett, A.K.1    Milligan, D.2    Prentice, A.G.3    Goldstone, A.H.4    McMullin, M.F.5    Hills, R.K.6
  • 8
    • 0037158110 scopus 로고    scopus 로고
    • The outcomes and costs of acute myeloid leukemia among the elderly
    • Menzin J., Lang K., Earle C.C., Kerney D., Mallick R. The outcomes and costs of acute myeloid leukemia among the elderly. Arch Intern Med 2002, 162:1597-1603.
    • (2002) Arch Intern Med , vol.162 , pp. 1597-1603
    • Menzin, J.1    Lang, K.2    Earle, C.C.3    Kerney, D.4    Mallick, R.5
  • 10
    • 55649106819 scopus 로고    scopus 로고
    • Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia
    • Roboz G.J., Ritchie E.K., Curcio T., Provenzano J., Carlin R., Samuel M., et al. Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia. Cancer 2008, 113:2504-2511.
    • (2008) Cancer , vol.113 , pp. 2504-2511
    • Roboz, G.J.1    Ritchie, E.K.2    Curcio, T.3    Provenzano, J.4    Carlin, R.5    Samuel, M.6
  • 11
    • 66549129197 scopus 로고    scopus 로고
    • Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide
    • Karp J.E., Flatten K., Feldman E.J., Greer J.M., Loegering D.A., Ricklis R.M., et al. Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide. Blood 2009, 113:4841-4852.
    • (2009) Blood , vol.113 , pp. 4841-4852
    • Karp, J.E.1    Flatten, K.2    Feldman, E.J.3    Greer, J.M.4    Loegering, D.A.5    Ricklis, R.M.6
  • 12
    • 33847001315 scopus 로고    scopus 로고
    • A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
    • Lancet J.E., Gojo I., Gotlib J., Feldman E.J., Greer J., Liesveld J.L., et al. A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia. Blood 2007, 109:1387-1394.
    • (2007) Blood , vol.109 , pp. 1387-1394
    • Lancet, J.E.1    Gojo, I.2    Gotlib, J.3    Feldman, E.J.4    Greer, J.5    Liesveld, J.L.6
  • 13
    • 77649282032 scopus 로고    scopus 로고
    • Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial
    • Raza A., Jurcic J.G., Roboz G.J., Maris M., Stephenson J.J., Wood B.L., et al. Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial. Leuk Lymphoma 2009, 50:1336-1344.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1336-1344
    • Raza, A.1    Jurcic, J.G.2    Roboz, G.J.3    Maris, M.4    Stephenson, J.J.5    Wood, B.L.6
  • 14
    • 62949087552 scopus 로고    scopus 로고
    • A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response
    • Pratz K.W., Cortes J., Roboz G.J., Rao N., Arowojolu O., Stine A., et al. A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response. Blood 2009, 113:3938-3946.
    • (2009) Blood , vol.113 , pp. 3938-3946
    • Pratz, K.W.1    Cortes, J.2    Roboz, G.J.3    Rao, N.4    Arowojolu, O.5    Stine, A.6
  • 15
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia
    • Cheson B.D., Bennett J.M., Kopecky K.J., Buchner T., Willman C.L., Estey E.H., et al. Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia. J Clin Oncol 2003, 21:4642-4649.
    • (2003) J Clin Oncol , vol.21 , pp. 4642-4649
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3    Buchner, T.4    Willman, C.L.5    Estey, E.H.6
  • 16
    • 35048820182 scopus 로고    scopus 로고
    • Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemia
    • Baz R., Rodriguez C., Fu A.Z., Jawde R.A., Kalaycio M., Advani A., et al. Impact of remission induction chemotherapy on survival in older adults with acute myeloid leukemia. Cancer 2007, 110:1752-1759.
    • (2007) Cancer , vol.110 , pp. 1752-1759
    • Baz, R.1    Rodriguez, C.2    Fu, A.Z.3    Jawde, R.A.4    Kalaycio, M.5    Advani, A.6
  • 17
    • 77449149373 scopus 로고    scopus 로고
    • Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
    • Fenaux P., Mufti G.J., Hellstrom-Lindberg E., Santini V., Gattermann N., Germing U., et al. Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia. J Clin Oncol 2009, 28:562-569.
    • (2009) J Clin Oncol , vol.28 , pp. 562-569
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3    Santini, V.4    Gattermann, N.5    Germing, U.6
  • 18
    • 77952140672 scopus 로고    scopus 로고
    • Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine
    • Blum W., Garzon R., Klisovic R.B., Schwind S., Walker A., Geyer S., et al. Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine. Proc Natl Acad Sci USA 2010, 107:7473-7478.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7473-7478
    • Blum, W.1    Garzon, R.2    Klisovic, R.B.3    Schwind, S.4    Walker, A.5    Geyer, S.6
  • 19
    • 81255161073 scopus 로고    scopus 로고
    • Results from a randomized phase III trial of decitabine versus supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed AML
    • Thomas X.G., Dmoszynska A., Wierzbowska A., Kuliczkowski K., Mayer J., Shelekhova T., et al. Results from a randomized phase III trial of decitabine versus supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed AML. J Clin Oncol 2011.
    • (2011) J Clin Oncol
    • Thomas, X.G.1    Dmoszynska, A.2    Wierzbowska, A.3    Kuliczkowski, K.4    Mayer, J.5    Shelekhova, T.6
  • 20
    • 77951649470 scopus 로고    scopus 로고
    • Effect of age on outcome of reduced-intensity hematopoietic cell transplantation for older patients with acute myeloid leukemia in first complete remission or with myelodysplastic syndrome
    • McClune B.L., Weisdorf D.J., Pedersen T.L., Tunes da Silva G., Tallman M.S., Sierra J., et al. Effect of age on outcome of reduced-intensity hematopoietic cell transplantation for older patients with acute myeloid leukemia in first complete remission or with myelodysplastic syndrome. J Clin Oncol 2010, 28:1878-1887.
    • (2010) J Clin Oncol , vol.28 , pp. 1878-1887
    • McClune, B.L.1    Weisdorf, D.J.2    Pedersen, T.L.3    da Tunes, S.G.4    Tallman, M.S.5    Sierra, J.6


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