NASCA-HMBC, a new NMR methodology for the resolution of severely overlapping signals: Application to the study of agathisflavone

Phytochemical Analysis

Volumn 23, Issue 2, 2012, Pages 126-130

  Bayiha Ba Njock, Gaétan ^a,b   Bartholomeusz, Trixie Ann ^a   Foroozandeh, Mohammadali ^a   Pegnyemb, Dieudonné Emmanuel ^b   Christen, Philippe ^a   Jeannerat, Damien ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

biflavonoids; high spectral resolution; NMR; Ouratea gilgiana; spectral aliasing

Indexed keywords

CARBON; SPECTRAL RESOLUTION;

ALIASED; BIFLAVONOID; HETERONUCLEAR; HIGH RESOLUTION; HIGH SPECTRAL RESOLUTION; LOWER RESOLUTION; ORDERS OF MAGNITUDE; OURATEA GILGIANA; SPECTRA'S; SPECTRAL ALIASING;

CHEMICAL SHIFT;

AGATHISFLAVONE; BIFLAVONOID; CARBON; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; HETERONUCLEAR MULTIPLE BOND CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MEDICINAL PLANT; NONAMBIGUOUS ASSIGNMENT BY SUPERPOSITION OF COUPLED ALIASED HETERONUCLEAR MULTIPLE BOND CORRELATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTICAL RESOLUTION; OURATEA GILGIANA; SIGNAL DETECTION; THIN LAYER CHROMATOGRAPHY;

OURATEA;

EID: 84857232412     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1333     Document Type: Article

References (17)

1. Abouem à Zintchem A, Atchadé AdT, Ghogomu Tih R, Tanyi Mbafor J, Blond A, Pegnyemb DE, Bodo B,. 2007. Flavonoids from Ouratea staudtii Van Tiegh. (ex Keay) (Ochnaceae). Biochem Syst Ecol 35: 255-256. (Pubitemid 46357506)
2. Baskyr I, Brand T, Findeisen M, Berger S,. 2006. Acquisition regime for high-resolution heteronuclear 2D NMR spectra. Angew Chem Int Edit 45: 7821-7824. (Pubitemid 44871353)
3. Bayiha Ba Njock G, Pegnyemb DE, Bartholomeusz TA, Christen P, Vitorge B, Nuzillard J-M, Shivapurkar R, Foroozandeh M, Jeannerat D,. 2010. Spectral aliasing: A super zoom for 2D-NMR Spectra. Principles and applications. Chimia 64: 235-240.
4. Boehlen JM, Rey M, Bodenhausen G,. 1989. Refocusing with chirped pulses for broadband excitation without phase dispersion. J Magn Reson 84: 191-197.
5. Chari VM, Ilyas M, Wagner H, Neszmelyi A, Chen F-C, Chen L-K, Lin Y-C, Lin Y-M,. 1977. Carbon-13 NMR spectroscopy of biflavanoids. Phytochemistry 16: 1273-1278.
6. Cicero DO, Barbato G, Bazzo R,. 2001. Sensitivity enhancement of a two-dimensional experiment for the measurement of heteronuclear long-range coupling constants, by a new scheme of coherence selection by gradients. J Magn Reson 148: 209-213.
7. 13C resolution in semi-selective HMBC: A band-selective, constant-time HMBC for complex organic structure elucidation by NMR. Org Biomol Chem 1: 3632-3634.
8. de Carvalho MG, de Albuquerque LRM, Mendes LdS, Guilhon GMSP, Rodrigues ST,. 2008. Biflavonoids and terpenoids isolated from the leaves of Ouratea microdonta Engl. (Ochnaceae). Rev Latinoam Quim 36: 71-75.
9. Eggenberger U, Pfändler P, Bodenhausen G,. 1988. Folding and pattern recognition in two-dimensional NMR spectra J Magn Reson 77: 192-196.
10. Foroozandeh M, Jeannerat D,. 2010. Deciphered chemical shifts in aliased spectra recorded with two slightly different narrow windows or differential chemical shift evolution. ChemPhysChem 11: 2503-2505.
11. Jeannerat D,. 2007. Computer optimized spectral aliasing in the indirect dimension of H-1-C-13 heteronuclear 2D NMR experiments. A new algorithm and examples of applications to small molecules. J Magn Reson 186: 112-122. (Pubitemid 46635252)
12. Jeannerat D, Ronan D, Haudry Y, Pinto A, Saulnier JP, Matile S,. 2004. NMR characterization of complex p-oligophenyl scaffolds by means of aliasing techniques to obtain resolution-enhanced two-dimensional spectra. Helv Chim Acta 87: 2190-2207. (Pubitemid 39371890)
13. Meselhy MR,. 2003. Constituents from Moghat, the roots of Glossostemon bruguieri (Desf.). Molecules 8: 614-621. (Pubitemid 39007549)
14. Ngo Mbing J, Enguehard-Gueiffier C, Atchade AdT, Allouchi H, Gangoue-Pieboji J, Mbafor JT, Tih RG, Pothier J, Pegnyemb DE, Gueiffier A,. 2006. Two biflavonoids from Ouratea nigroviolacea. Phytochemistry 67: 2666-2670.
15. Pegnyemb DE, Mbing JN, De Theodore Atchade A, Tih RG, Sondengam BL, Blond A, Bodo B,. 2005. Antimicrobial biflavonoids from the aerial parts of Ouratea sulcata. Phytochemistry 66: 1922-1926. (Pubitemid 41207695)
16. Schmieder P, Zimmer S, Kessler H,. 1991. Increased resolution in proton detected heteronuclear NMR experiments by folding in the hetero-dimension. Magn Reson Chem 29: 375-380.
17. Vitorge B, Bieri S, Humam M, Christen P, Hostettmann K, Muñoz O, Loss S, Jeannerat D,. 2009. High-precision heteronuclear 2D NMR experiments using 10-ppm spectral window to resolve carbon overlap. Chem Commun 950-952.