Association between statin medication use and improved outcomes during inpatient rehabilitation in older people

Age and Ageing

Volumn 41, Issue 2, 2012, Pages 260-262

  Lynch, Joanna E ^a   Henderson, Neil R ^a   Ramage, Lynn ^a   McMurdo, Marion E T ^b   Witham, Miles D ^b  

^a NHS TAYSIDE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Elderly; Functional gains; Rehabilitation; Statins

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

AGED; ARTICLE; COMORBIDITY; CONTROLLED STUDY; DRUG USE; FEMALE; FRACTURE; GERIATRIC REHABILITATION; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; STROKE;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; CHI-SQUARE DISTRIBUTION; COMORBIDITY; FEMALE; HEALTH STATUS; HOSPITALS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INPATIENTS; LENGTH OF STAY; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; PATIENT DISCHARGE; RECOVERY OF FUNCTION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SCOTLAND; TIME FACTORS; TREATMENT OUTCOME;

EID: 84857213056     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afr159     Document Type: Article

References (12)

1. Shepherd J, Blauw GJ, Murphy MB et al., PROSPER study group. Pravatatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet 2002; 360: 1623-30.
2. Hippisley-Cox J, Coupland C. Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. BMJ 2010; 340: c2197.
3. Kamper AM, Stott DJ, Hyland M, Murray HM, Ford I; for the PROSPER study group. Predictors of functional decline in elderly people with vascular risk factors or disease. Age Ageing 2005; 34: 450-5.
4. Buford TW, Anton SD, Judge AR et al. Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy. Ageing Res Rev 2010; 9: 369-83.
5. Sumukadas D, Witham MD, Struthers AD, McMurdo MET. Effect of perindopril on physical function in elderly people with functional impairment: a randomised controlled trial. CMAJ 2007; 177: 867-74.
6. Janda JS, Young A, Fitzgerald JM, Etminan M, Swiston J. The effects of statins on mortality from severe infections and sepsis: a systematic review and metaanalysis. J Critical Care 2010; 25: 656.e7-22 [Epub 2010 Apr 22].
7. Douglas I, Evans S, Smeeth L. Effect of statin treatment on short-term mortality after pneumonia episode: cohort study. BMJ 2011; 342: d1642.
8. Chalmers JD, Short PM, Akram AR, Hill AT. Statins in community acquired pneumonia: evidence from experimental and clinical studies. Resp Med 2010; 108: 1081-91.
9. Witham MD, Sumakadas D, McMurdo MET. ACE inhibitors for sarcopenia: as good as exercise training? Age Ageing 2008; 37: 363-5.
10. Krishnan GM, Thompson PD. The effects of statins on skeletal muscle strength and exercise performance. Curr Opin Lipidol 2010; 21: 324-28.
11. Witham MD, Ramage L, Burns SL et al. Trends in function and post-discharge mortality in a medicine for the elderly rehabilitation centre over a 10 year period. Arch Phys Med Rehab 2011; 92: 1288-92.
12. Wade DT, Collin C. The Barthel ADL Index: a standard measure of physical disability? Int Disabil Stud 1988; 10: 64-7.