Radiofrequency catheter ablation of pulmonary vein roots results in axonal degeneration of distal epicardial nerves

Autonomic Neuroscience: Basic and Clinical

Volumn 167, Issue 1-2, 2012, Pages 61-65

  Puodziukynas, Aras ^a   Kazakevicius, Tomas ^a   Vaitkevicius, Raimundas ^a   Rysevaite, Kristina ^a   Jokubauskas, Marius ^a   Saburkina, Inga ^a   Sladkeviciute Dirzinauskiene, Vaiva ^a   Dirzinauskas, Evaldas ^a   Zabiela, Vytautas ^a   Sileikis, Vytautas ^a   Plisiene, Jurgita ^a   Pauziene, Neringa ^a   Zaliunas, Remigijus ^a   Jalife, José ^b   Pauza, Dainius H ^a  

^a LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Atrial fibrillation; Cardiac nerves; Denervation; Ganglionated plexi; Heart; Pulmonary veins; Radiofrequency ablation

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINE ACETYLTRANSFERASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATHETER ABLATION; CONTROLLED STUDY; CORONARY SINUS; ELECTRON MICROSCOPY; FEMALE; HEART LEFT VENTRICLE; HISTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; MYELINATED NERVE; NERVE FIBER DEGENERATION; NERVE PLEXUS; NONHUMAN; NONMYELINATED NERVE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PULMONARY VEIN; SCHWANN CELL; SHEEP; THERAPY EFFECT; TRANSMISSION ELECTRON MICROSCOPY;

ACETYLCHOLINESTERASE; ANIMALS; AXONS; CATHETER ABLATION; CHOLINE O-ACETYLTRANSFERASE; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE DEGENERATION; NERVE FIBERS; NERVE FIBERS, MYELINATED; PERICARDIUM; PULMONARY VEINS; SCHWANN CELLS; SHEEP; THORACOTOMY; TYROSINE 3-MONOOXYGENASE;

EID: 84857192457     PISSN: 15660702     EISSN: 18727484     Source Type: Journal    
DOI: 10.1016/j.autneu.2012.01.001     Document Type: Article

References (15)

1. Armour J.A., Kember G.C. Cardiac sensory neurons. Basic and clinical neurocardiology 2004, 79-117. Oxford University Press, NY. J.A. Armour, J.L. Ardell (Eds.).
2. Bagge L., Blomström P., Nilsson L., Einarsson G.M., Jidéus L., Blomström-Lundqvist C. Epicardial off-pump pulmonary vein isolation and vagal denervation improve long-term outcome and quality of life in patients with atrial fibrillation. J. Thorac. Cardiovasc. Surg. 2009, 137:1265-1271.
3. Bertaglia E., Tondo C., De Simone A., Zoppo F., Mantica M., Turco P., Iuliano A., Forleo G., La Rocca V., Stabile G. Does catheter ablation cure atrial fibrillation? Single-procedure outcome of drug-refractory atrial fibrillation ablation: a 6-year multicentre experience. Europace 2010, 12:181-187.
4. Capulzini L., Chierchia G.B., Sarkozy A., Paparella G., de Asmundis C., Brugada P. Extreme bradycardia during pulmonary vein isolation: keep on ablating in that region?. J. Cardiovasc. Med. (Hagerstown) 2009, 10:267-270.
5. Han F.T., Kasirajan V., Kowalski M., Kiser R., Wolfe L., Kalahasty G., Shepard R.K., Wood M.A., Ellenbogen K.A. Results of a minimally invasive surgical pulmonary vein isolation and ganglionic plexi ablation for atrial fibrillation: single-center experience with 12-month follow-up. Circ. Arrhythm. Electrophysiol. 2009, 2:370-377.
6. Kamada S., Kawamura Y., Iida Y., Sato N., Hasebe N. An experimental study on the site dependency and mechanism of vagal denervation following radiofrequency catheter ablation for supraventricular arrhythmias including atrial fibrillation. Int. Heart J. 2008, 49:493-506.
7. Levy M.N., Warner M.R. Parasympathetic effects on cardiac function. Neurocardiology 1994, 53-76. Oxford University Press, New York. J.A. Armour, J.L. Ardell (Eds.).
8. Marron K., Wharton J., Sheppard M.N., Fagan D., Royston D., Kuhn D.M., de Leval M.R., Whitehead B.F., Anderson R.H., Polak J.M. Distribution, morphology, and neurochemistry of endocardial and epicardial nerve terminal arborizations in the human heart. Circulation 1995, 92:2343-2351.
9. Oh S., Zhang Y., Bibevski S., Marrouche N.F., Natale A., Mazgalev T.N. Vagal denervation and atrial fibrillation inducibility: epicardial fat pad ablation does not have long-term effects. Hear. Rhythm. 2006, 3:701-708.
10. Po S.S., Scherlag B.J., Yamanashi W.S., Edwards J., Zhou J., Wu R., Geng N., Lazzara R., Jackman W.M. Experimental model for paroxysmal atrial fibrillation arising at the pulmonary vein-atrial junctions. Hear. Rhythm. 2006, 3:201-208.
11. Saburkina I., Rysevaite K., Pauziene N., Mischke K., Schauerte P., Jalife J., Pauza D.H. Epicardial neural ganglionated plexus of ovine heart: anatomic basis for experimental cardiac electrophysiology and nerve protective cardiac surgery. Hear. Rhythm. 2010, 7:942-950.
12. Sakamoto S., Schuessler R.B., Lee A.M., Aziz A., Lall S.C., Damiano R.J. Vagal denervation and reinnervation after ablation of ganglionated plexi. J. Thorac. Cardiovasc. Surg. 2010, 139:444-452.
13. Takahashi Y., Jais P., Hocini M., Sanders P., Rotter M., Rostock T., Hsu L.F., Sacher F., Clementy J., Haissaguerre M. Shortening of fibrillatory cycle length in the pulmonary vein during vagal excitation. J. Am. Coll. Cardiol. 2006, 47:774-780.
14. Tsuboi M., Furukawa Y., Nakajima K., Kurogouchi F., Chiba S. Inotropic, chronotropic, and dromotropic effects mediated via parasympathetic ganglia in the dog heart. Am. J. Physiol. Heart Circ. Physiol. 2000, 279:H1201-H1207.
15. Zhao Q.Y., Huang H., Zhang S.D., Tang Y.H., Wang X., Zhang Y.G., Salim M., Okello E., Deng H.P., Yu S.B., Huang C.X. Atrial autonomic innervation remodelling and atrial fibrillation inducibility after epicardial ganglionic plexi ablation. Europace 2010, 12:805-810.