In vivo implantation of tissue-engineered human nasal septal neocartilage constructs: A pilot study

Otolaryngology - Head and Neck Surgery

Volumn 146, Issue 1, 2012, Pages 46-52

  Chang, Angela A ^a   Reuther, Marsha S ^a   Briggs, Kristen K ^b   Schumacher, Barbara L ^b   Williams, Gregory M ^b   Corr, Maripat ^a   Sah, Robert L ^b   Watson, Deborah ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cartilage tissue engineering; Human septal cartilage; In vivo tissue engineering; Murine; Nude mouse

Indexed keywords

ALGINIC ACID; COLLAGEN TYPE 1; GLYCOSAMINOGLYCAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL MATURATION; CHONDROCYTE IMPLANTATION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MOUSE; NONHUMAN; NOSE CARTILAGE; NOSE SEPTUM RECONSTRUCTION; TISSUE ENGINEERING; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; FOLLOW UP; GRAFT SURVIVAL; NOSE INJURY; NOSE SEPTUM; NUDE MOUSE; PILOT STUDY; PROSPECTIVE STUDY; TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; GRAFT SURVIVAL; HUMANS; MICE; MICE, NUDE; NASAL CARTILAGES; NASAL SEPTUM; NOSE DEFORMITIES, ACQUIRED; PILOT PROJECTS; PROSPECTIVE STUDIES; TISSUE ENGINEERING; TREATMENT OUTCOME;

EID: 84857178063     PISSN: 01945998     EISSN: 10976817     Source Type: Journal    
DOI: 10.1177/0194599811425141     Document Type: Article

References (21)

1. Tardy ME Jr, Denneny J III, Fritsch MH. The versatile cartilage autograft in reconstruction of the nose and face. Laryngoscope. 1985;95:523-533. (Pubitemid 15021386)
2. Komender J, Marczynski W, Tylman D, Malczewska H, Komender A, Sladowski D. Preserved tissue allografts in reconstructive surgery. Cell Tissue Bank. 2001;2:103-112. (Pubitemid 34240370)
3. Collawn SS, Fix RJ, Moore JR, Vasconez LO. Nasal cartilage grafts: more than a decade of experience. Plast Reconstr Surg. 1997;100:1547-1552. (Pubitemid 27508219)
4. Romo T III, McLaughlin LA, Levine JM, Sclafani AP. Nasal implants: autogenous, semisynthetic, and synthetic. Facial Plast Surg Clin North Am. 2002;10:155-166.
5. Duda GN, Haisch A, Endres M, et al. Mechanical quality of tissue engineered cartilage: results after 6 and 12 weeks in vivo. J Biomed Mater Res. 2000;53:673-677.
6. Eyrich D, Wiese H, Maier G, et al. In vitro and in vivo cartilage engineering using a combination of chondrocyte-seeded long-term stable fibrin gels and polycaprolactone-based polyurethane scaffolds. Tissue Eng. 2007;13:2207-2218. (Pubitemid 47404436)
7. Kitahara S, Nakagawa K, Sah RL, et al. In vivo maturation of scaffold-free engineered articular cartilage on hydroxyapatite. Tissue Eng Part A. 2008;14:1905-1913.
8. Masuda K, Sah RL, Hejna MJ, Thonar EJ. A novel twostep method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method. J Orthop Res. 2003;21:139-148. (Pubitemid 36157631)
9. Alexander TH, Sage AB, Chen AC, et al. IGF-1 and GDF-5-promote the formation of tissue-engineered human nasal septal cartilage. Tissue Eng Part C Methods. 2010;16:1213-1221.
10. Scott JE, Dorling J. Differential staining of acid glycosaminoglycans (mucopolysaccharides) by Alcian blue in salt solutions. Histochem Cell Biol. 1965;5:221-233.
11. Homicz MR, McGowan KB, Lottman LM, Beh G, Sah RL, Watson D. A compositional analysis of human nasal septal cartilage. Arch Facial Plast Surg. 2003;5:53-58.
12. McGowan KB, Kurtis MS, Lottman LM, Watson D, Sah RL. Biochemical quantification of DNA in human articular and septal cartilage using PicoGreen and Hoechst 33258. Osteoarthritis Cartilage. 2002;10:580-587. (Pubitemid 34919074)
13. Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta. 1986;883:173-177. (Pubitemid 16027978)
14. Richmon JD, Sage AB, Wong VW, et al. Tensile biomechanical properties of human nasal septal cartilage. Am J Rhinol. 2005;19:617-622. (Pubitemid 43115812)
15. Vetter U, Pirsig W, Helbing D, Heit W, Heinze E. Patterns of growth in human septal cartilage: a review of new approaches. Int J Pediatr Otorhinolaryngol. 1984;7:63-74. (Pubitemid 14146028)
16. Williamson AK, Masuda K, Thonar EJ, Sah RL. Growth of immature articular cartilage in vitro: correlated variation in tensile biomechanical and collagen network properties. Tissue Eng. 2003;9:625-634. (Pubitemid 37048105)
17. Asanbaeva A, Masuda K, Thonar EJ, Klisch SM, Sah RL. Mechanisms of cartilage growth: modulation of balance between proteoglycan and collagen in vitro using chondroitinase ABC. Arthritis Rheum. 2007;56:188-198. (Pubitemid 46106191)
18. Rotter N, Aigner J, Naumann A, Hammer C, Sittinger M. Behavior of tissue-engineered human cartilage after transplantation into nude mice. J Mater Sci Mater Med. 1999;10:689-693.
19. Haisch A, Duda GN, Schroeder D, et al. The morphology and biomechanical characteristics of subcutaneously implanted tissue-engineered human septal cartilage. Eur Arch Otorhinolaryngol. 2005;262:993-997. (Pubitemid 41798021)
20. Farhadi J, Fulco I, Miot S, et al. Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery. Ann Surg. 2006;244:978-985. (Pubitemid 44808638)
21. Dobratz EJ, Kim SW, Voglewede A, Park SS. Injectable cartilage: using alginate and human chondrocytes. Arch Facial Plast Surg. 2009;11:40-47.