메뉴 건너뛰기




Volumn 7, Issue 2, 2012, Pages

Incidence and risk of QTc interval prolongation among cancer patients treated with vandetanib: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ERLOTINIB; GEFITINIB; PLACEBO; VANDETANIB; N (4 BROMO 2 FLUOROPHENYL) 6 METHOXY 7 ((1 METHYLPIPERIDIN 4 YL)METHOXY)QUINAZOLIN 4 AMINE; N-(4-BROMO-2-FLUOROPHENYL)-6-METHOXY-7-((1-METHYLPIPERIDIN-4-YL)METHOXY)QUINAZOLIN-4-AMINE; PIPERIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE;

EID: 84857158314     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030353     Document Type: Review
Times cited : (82)

References (38)
  • 1
    • 0037115405 scopus 로고    scopus 로고
    • ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
    • Carlomagno F, Vitagliano D, Guida T, Ciardiello F, Tortora G, et al. (2002) ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. Cancer Res 62: 7284-7290.
    • (2002) Cancer Res , vol.62 , pp. 7284-7290
    • Carlomagno, F.1    Vitagliano, D.2    Guida, T.3    Ciardiello, F.4    Tortora, G.5
  • 2
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
    • Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Chester R, et al. (2002) ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res 62: 4645-4655.
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3    Kendrew, J.4    Chester, R.5
  • 3
    • 77649214078 scopus 로고    scopus 로고
    • Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer
    • Wells SA, Gosnell JE, Gagel RF, Moley J, Pfister D, et al. (2010) Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer. J Clin Oncol 28: 767-772.
    • (2010) J Clin Oncol , vol.28 , pp. 767-772
    • Wells, S.A.1    Gosnell, J.E.2    Gagel, R.F.3    Moley, J.4    Pfister, D.5
  • 4
    • 84863172871 scopus 로고    scopus 로고
    • Vandetanib in locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind Phase III Trial (ZETA): Poster (1007PD) presented to ESMO conference in October 2010
    • Wells SA, et al. Vandetanib in locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind Phase III Trial (ZETA): Poster (1007PD) presented to ESMO conference in October 2010.
    • Wells, S.A.1
  • 5
    • 84863172872 scopus 로고    scopus 로고
    • FDA approves new treatment for rare form of thyroid cancer
    • April 6,2011. (accessed April 17, 2011)
    • Anon, FDA approves new treatment for rare form of thyroid cancer. www.fda.gov April 6,2011.http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm250168.htm (accessed April 17, 2011).
    • Anon1
  • 6
    • 77954035012 scopus 로고    scopus 로고
    • Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial
    • Herbst RS, Sun Y, Eberhardt WE, Germonpre P, Saijo N, et al. (2010) Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. Lancet Oncol 11: 619-626.
    • (2010) Lancet Oncol , vol.11 , pp. 619-626
    • Herbst, R.S.1    Sun, Y.2    Eberhardt, W.E.3    Germonpre, P.4    Saijo, N.5
  • 7
    • 66349087009 scopus 로고    scopus 로고
    • Vandetanib versus gefitinib in patients with advanced non-small-cell lung cancer: results from a two-part, double-blind, randomized phase ii study
    • Natale RB, Bodkin D, Govindan R, Sleckman BG, Rizvi NA, et al. (2009) Vandetanib versus gefitinib in patients with advanced non-small-cell lung cancer: results from a two-part, double-blind, randomized phase ii study. J Clin Oncol 27: 2523-2529.
    • (2009) J Clin Oncol , vol.27 , pp. 2523-2529
    • Natale, R.B.1    Bodkin, D.2    Govindan, R.3    Sleckman, B.G.4    Rizvi, N.A.5
  • 8
    • 84863117978 scopus 로고    scopus 로고
    • Vandetanib in locally advanced or metastatic differentiated thyroid cancer (papillary or follicular;DTC): a randomized, double-blind phase II trial;Poster (1008 PD) presented to ESMO conference in October 2010
    • Leboulleux S, Bastholt L, et al. Vandetanib in locally advanced or metastatic differentiated thyroid cancer (papillary or follicular;DTC): a randomized, double-blind phase II trial;Poster (1008 PD) presented to ESMO conference in October 2010.
    • Leboulleux, S.1    Bastholt, L.2
  • 9
    • 79955882203 scopus 로고    scopus 로고
    • Vandetanib plus mFOLFOX6 in patients with advanced colorectal cancer (CRC): A randomized, double-blind, placebo-controlled phase II study
    • (suppl; abstr 4084)
    • Yang TS, Oh DY, Guimbaud R, et al. (2009) Vandetanib plus mFOLFOX6 in patients with advanced colorectal cancer (CRC): A randomized, double-blind, placebo-controlled phase II study. J Clin Oncol 27: 15s (suppl; abstr 4084).
    • (2009) J Clin Oncol , vol.27
    • Yang, T.S.1    Oh, D.Y.2    Guimbaud, R.3
  • 10
    • 66249113517 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer
    • Horti J, Widmark A, Stenzl A, Federico MH, Abratt RP, et al. (2009) A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer. Cancer Biother Radiopharm 24: 175-180.
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 175-180
    • Horti, J.1    Widmark, A.2    Stenzl, A.3    Federico, M.H.4    Abratt, R.P.5
  • 11
    • 84863153215 scopus 로고    scopus 로고
    • Evaluation of vandetanib in patients with inoperable hepatocellular carcinoma (HCC): a randomized, double-blind, parallel group, multicentre, phase II study.Joint ECCO 15-34TH ESMO Multidisciplinary Congress 2009,Abstract No: PD-6518. Accessed November 2, 2009
    • Hsu C, Yang TS, Huo TL, et al. Evaluation of vandetanib in patients with inoperable hepatocellular carcinoma (HCC): a randomized, double-blind, parallel group, multicentre, phase II study.Joint ECCO 15-34TH ESMO Multidisciplinary Congress 2009,Abstract No: PD-6518. Accessed November 2, 2009.
    • Hsu, C.1    Yang, T.S.2    Huo, T.L.3
  • 14
    • 79952748468 scopus 로고    scopus 로고
    • Phase III trial of vandetanib compared with erlotinib in patients with previously treated advanced non-small-cell lung cancer
    • Natale RB, Thongprasert S, Greco FA, Thomas M, Tsai CM, et al. (2011) Phase III trial of vandetanib compared with erlotinib in patients with previously treated advanced non-small-cell lung cancer. J Clin Oncol 29: 1059-1066.
    • (2011) J Clin Oncol , vol.29 , pp. 1059-1066
    • Natale, R.B.1    Thongprasert, S.2    Greco, F.A.3    Thomas, M.4    Tsai, C.M.5
  • 15
    • 41749097667 scopus 로고    scopus 로고
    • A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer
    • Kiura K, Nakagawa K, Shinkai T, Eguchi K, Ohe Y, et al. (2008) A randomized, double-blind, phase IIa dose-finding study of Vandetanib (ZD6474) in Japanese patients with non-small cell lung cancer. J Thorac Oncol 3: 386-393.
    • (2008) J Thorac Oncol , vol.3 , pp. 386-393
    • Kiura, K.1    Nakagawa, K.2    Shinkai, T.3    Eguchi, K.4    Ohe, Y.5
  • 16
    • 84874111474 scopus 로고    scopus 로고
    • CTC v 2.0 and Common Terminology Criteria for Adverse Events Criteria V3.0 (CTCAE)
    • National Cancer Institute, (accessed April 2, 2011)
    • National Cancer Institute CTC v 2.0 and Common Terminology Criteria for Adverse Events Criteria V3.0 (CTCAE). http://ctep.cancer.gov/reporting/ctc.html (accessed April 2, 2011).
  • 18
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, et al. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17: 1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3    Jenkinson, C.4    Reynolds, D.J.5
  • 20
    • 84890783342 scopus 로고    scopus 로고
    • Analysing data and undertaking meta-analyses
    • Cochrane Handbook for Systematic Reviews of Interventions 5.1.0. The Cochrane Collaboration,
    • Higgins JPT, Green S, eds. (2011) Analysing data and undertaking meta-analyses. Cochrane Handbook for Systematic Reviews of Interventions 5.1.0. The Cochrane Collaboration,http://www.cochrane-handbook.org.
    • (2011)
    • Higgins, J.P.T.1    Green, S.2
  • 21
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M, (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics Dec;50 (4): 1088-1101.
    • (1994) Biometrics Dec , vol.50 , Issue.4 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 22
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C, (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 23
    • 34948844052 scopus 로고    scopus 로고
    • Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20
    • Arnold AM, Seymour L, Smylie M, Ding K, Ung Y, et al. (2007) Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20. J Clin Oncol 25: 4278-4284.
    • (2007) J Clin Oncol , vol.25 , pp. 4278-4284
    • Arnold, A.M.1    Seymour, L.2    Smylie, M.3    Ding, K.4    Ung, Y.5
  • 24
    • 56749102822 scopus 로고    scopus 로고
    • Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer
    • Heymach JV, Paz-Ares L, De Braud F, Sebastian M, Stewart DJ, et al. (2008) Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol 26: 5407-5415.
    • (2008) J Clin Oncol , vol.26 , pp. 5407-5415
    • Heymach, J.V.1    Paz-Ares, L.2    de Braud, F.3    Sebastian, M.4    Stewart, D.J.5
  • 25
    • 18244387980 scopus 로고    scopus 로고
    • A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer
    • Miller KD, Trigo JM, Wheeler C, Barge A, Rowbottom J, et al. (2005) A multicenter phase II trial of ZD6474, a vascular endothelial growth factor receptor-2 and epidermal growth factor receptor tyrosine kinase inhibitor, in patients with previously treated metastatic breast cancer. Clin Cancer Res 11: 3369-3376.
    • (2005) Clin Cancer Res , vol.11 , pp. 3369-3376
    • Miller, K.D.1    Trigo, J.M.2    Wheeler, C.3    Barge, A.4    Rowbottom, J.5
  • 26
    • 0141939058 scopus 로고    scopus 로고
    • Effect of arsenic trioxide on QT interval in patients with advanced malignancies
    • Barbey JT, Pezzullo JC, Soignet SL, (2003) Effect of arsenic trioxide on QT interval in patients with advanced malignancies. J Clin Oncol 21: 3609-3615.
    • (2003) J Clin Oncol , vol.21 , pp. 3609-3615
    • Barbey, J.T.1    Pezzullo, J.C.2    Soignet, S.L.3
  • 27
    • 0141576728 scopus 로고    scopus 로고
    • Baseline heart rate-corrected QT and eligibility for clinical trials in oncology
    • Varterasian M, Meyer M, Fingert H, Radlowski D, Asbury P, et al. (2003) Baseline heart rate-corrected QT and eligibility for clinical trials in oncology. J Clin Oncol 21: 3378-3379.
    • (2003) J Clin Oncol , vol.21 , pp. 3378-3379
    • Varterasian, M.1    Meyer, M.2    Fingert, H.3    Radlowski, D.4    Asbury, P.5
  • 28
    • 77955936651 scopus 로고    scopus 로고
    • Prolonged QTc interval in cancer therapeutic drug development: defining arrhythmic risk in malignancy
    • Brell JM, (2010) Prolonged QTc interval in cancer therapeutic drug development: defining arrhythmic risk in malignancy. Prog Cardiovasc Dis 53: 164-172.
    • (2010) Prog Cardiovasc Dis , vol.53 , pp. 164-172
    • Brell, J.M.1
  • 29
    • 34548276036 scopus 로고    scopus 로고
    • Molecularly targeted oncology therapeutics and prolongation of the QT interval
    • Strevel EL, Ing DJ, Siu LL, (2007) Molecularly targeted oncology therapeutics and prolongation of the QT interval. J Clin Oncol 25: 3362-3371.
    • (2007) J Clin Oncol , vol.25 , pp. 3362-3371
    • Strevel, E.L.1    Ing, D.J.2    Siu, L.L.3
  • 30
    • 0034826856 scopus 로고    scopus 로고
    • Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval
    • Gillen MS, Miller B, Chaikin P, Morganroth J, (2001) Effects of supratherapeutic doses of ebastine and terfenadine on the QT interval. Br J Clin Pharmacol pp. 201-204.
    • (2001) Br J Clin Pharmacol , pp. 201-204
    • Gillen, M.S.1    Miller, B.2    Chaikin, P.3    Morganroth, J.4
  • 32
    • 0033305162 scopus 로고    scopus 로고
    • Regulation of rat cardiac Kv1.5 gene expression by thyroid hormone is rapid and chamber specific
    • Ojamaa K, Sabet A, Kenessey A, Shenoy R, Klein I, (1999) Regulation of rat cardiac Kv1.5 gene expression by thyroid hormone is rapid and chamber specific. Endocrinology 140: 3170-3176.
    • (1999) Endocrinology , vol.140 , pp. 3170-3176
    • Ojamaa, K.1    Sabet, A.2    Kenessey, A.3    Shenoy, R.4    Klein, I.5
  • 33
    • 49449106134 scopus 로고    scopus 로고
    • Subclinical hypothyroidism is characterized by increased QT interval dispersion among women
    • Bakiner O, Ertorer ME, Haydardedeoglu FE, Bozkirli E, Tutuncu NB, et al. (2008) Subclinical hypothyroidism is characterized by increased QT interval dispersion among women. Med Princ Pract 17: 390-394.
    • (2008) Med Princ Pract , vol.17 , pp. 390-394
    • Bakiner, O.1    Ertorer, M.E.2    Haydardedeoglu, F.E.3    Bozkirli, E.4    Tutuncu, N.B.5
  • 36
    • 0017330981 scopus 로고
    • Noninvasive evaluation of cardiac function in hypothyroidism. Response to gradual thyroxine replacement
    • Crowley WF, Ridgway EC, Bough EW, Francis GS, Daniels GH, et al. (1977) Noninvasive evaluation of cardiac function in hypothyroidism. Response to gradual thyroxine replacement. N Engl J Med 296: 1-6.
    • (1977) N Engl J Med , vol.296 , pp. 1-6
    • Crowley, W.F.1    Ridgway, E.C.2    Bough, E.W.3    Francis, G.S.4    Daniels, G.H.5
  • 37
    • 16544395427 scopus 로고    scopus 로고
    • Thyroid hormone and the cardiovascular system
    • Danzi S, Klein I, (2004) Thyroid hormone and the cardiovascular system. Minerva Endocrinol 29: 139-150.
    • (2004) Minerva Endocrinol , vol.29 , pp. 139-150
    • Danzi, S.1    Klein, I.2
  • 38
    • 79952742483 scopus 로고    scopus 로고
    • Vandetanib plus pemetrexed for the second-line treatment of advanced non-small-cell lung cancer: a randomized, double-blind phase III trial
    • de Boer RH, Arrieta O, Yang CH, Gottfried M, Chan V, et al. (2011) Vandetanib plus pemetrexed for the second-line treatment of advanced non-small-cell lung cancer: a randomized, double-blind phase III trial. J Clin Oncol 29: 1067-1074.
    • (2011) J Clin Oncol , vol.29 , pp. 1067-1074
    • de Boer, R.H.1    Arrieta, O.2    Yang, C.H.3    Gottfried, M.4    Chan, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.