Simultaneous determination of the azoles voriconazole, posaconazole, isavuconazole, itraconazole and its metabolite hydroxy-itraconazole in human plasma by reversed phase ultra-performance liquid chromatography with ultraviolet detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 887-888, Issue , 2012, Pages 79-84

  Verweij van Wissen, C P W G M ^a   Burger, D M ^a   Verweij, P E ^a   Aarnoutse, R E ^a   Bruggemann R J M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Analytical; Antifungal; Pharmacokinetics; Therapeutic drug monitoring

Indexed keywords

ACQUITY; ANALYTICAL; ANTI-FUNGAL; COEFFICIENTS OF VARIATIONS; CONCENTRATION RANGES; EXTRACTION RECOVERY; HUMAN PLASMAS; INTERNAL STANDARDS; ITRACONAZOLE; LIQUID-LIQUID EXTRACTION; PHARMACOKINETIC RESEARCH; PHENYL COLUMNS; QUANTITATIVE DETERMINATIONS; REVERSED PHASE; SIMULTANEOUS DETERMINATIONS; THERAPEUTIC DRUG MONITORING; ULTRA VIOLET DETECTION; ULTRAPERFORMANCE LIQUID CHROMATOGRAPHY; VORICONAZOLE;

LIQUID CHROMATOGRAPHY; METABOLISM; METABOLITES; PATIENT MONITORING; PHARMACOKINETICS;

BIOMOLECULES;

ABACAVIR; ACENOCOUMAROL; ACETYLSALICYLIC ACID; ACICLOVIR; AMITRIPTYLINE; AMOXICILLIN; AMPHOTERICIN B; AMPRENAVIR; CASPOFUNGIN; CLOFAZIMINE; DIAZEPAM; DOMPERIDONE; ERYTHROMYCIN; ETRAVIRINE; FLUOXETINE; GANCICLOVIR; HYDROXYITRACONAZOLE; IBUPROFEN; ISAVUCONAZOLE; ITRACONAZOLE; LAMIVUDINE; LIDOCAINE; LOPINAVIR; LORAZEPAM; PARACETAMOL; POSACONAZOLE; PYRROLE DERIVATIVE; UK 115794; UNCLASSIFIED DRUG; UNINDEXED DRUG; VORICONAZOLE;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; DRUG STABILITY; LIQUID LIQUID EXTRACTION; PRIORITY JOURNAL; REVERSED PHASE ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; SPECTRAL SENSITIVITY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

ANTIFUNGAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DRUG MONITORING; DRUG STABILITY; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TRIAZOLES;

EID: 84857141568     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.01.015     Document Type: Article

References (12)

1. Brüggemann R.J., Blijlevens N.M., Burger D.M., Franke B., Troke P.F., Donnelly J.P. J. Antimicrob. Chemother. 2010, 65:107.
2. Pascual A., Calandra T., Bolay S., Buclin T., Bille J., Marchetti O. Clin. Infect. Dis. 2008, 46:201.
3. Neely M., Rushing T., Kovacs A., Jelliffe R., Hoffman J. Clin. Infect. Dis. 2010, 50:27.
4. Jang S.H., Colangelo P.M., Gobburu J.V. Clin. Pharmacol. Ther. 2010, 88:115.
5. Lestner J.M., Roberts S.A., Moore C.B., Howard S.J., Denning D.W., Hope W.W. Clin. Infect. Dis. 2009, 49:928.
6. Gordien J.B., Pigneux A., Vigouroux S., Tabrizi R., Accoceberry I., Bernadou J.M., Rouault A., Saux M.C., Breilh D. J. Pharm. Biomed. Anal. 2009, 50:932.
7. Decosterd L.A., Rochat B., Pesse B., Mercier T., Tissot F., Widmer N., Bille J., Calandra T., Zanolari B., Marchetti O. Antimicrob. Agents Chemother. 2010, 54:5303.
8. Farowski F., Cornely O.A., Vehreschild J.J., Hartmann P., Bauer T., Steinbach A., Ruping M.J., Muller C. Antimicrob. Agents Chemother. 2010, 54:1815.
9. Alffenaar J.W., Wessels A.M., van H.K., Greijdanus B., Kosterink J.G., Uges D.R. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2010, 878:39.
10. US Department of Health and Human Services, Center for Drug Evaluation and Research and Food and Drug Administration, Guidance for the Industry: Bioanalytical Method Validation, (2001). Available at http://www.fda.gov/cder/guidance/index.htm.
11. Bruggemann R.J., van der Linden J.W., Verweij P.E., Burger D.M., Warris A. Pediatr. Infect. Dis. J. 2010.
12. Brüggemann R.J., Touw D.J., Aarnoutse R.E., Verweij P.E., Burger D.M. Antimicrob. Agents Chemother. 2009, 53:303.