Scrub typhus in children at a tertiary hospital in southern India: Clinical profile and complications

Journal of Infection and Public Health

Volumn 5, Issue 1, 2012, Pages 82-88

  Kumar, Manish ^a   Krishnamurthy, Sriram ^a   Delhikumar, C G ^a   Narayanan, Parameswaran ^a   Biswal, Niranjan ^a   Srinivasan, Sadagopan ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Acute kidney injury; Children; Myocarditis; Rickettsial infections; Scrub typhus

Indexed keywords

DOXYCYCLINE;

ACUTE KIDNEY FAILURE; ANICTERIC HEPATITIS; ARTICLE; CARDIOGENIC SHOCK; CHILD; CLINICAL ARTICLE; EDEMA; FEMALE; HEPATITIS; HEPATOMEGALY; HEPATOSPLENOMEGALY; HUMAN; HYPOTENSION; INDIA; LYMPHADENOPATHY; MALE; MYOCARDITIS; OBSERVATIONAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RASH; RICKETTSIACEAE INFECTION; SCHOOL CHILD; SCRUB TYPHUS; TERTIARY HEALTH CARE; THROMBOCYTOPENIA; TICK BITE; TREATMENT RESPONSE;

ACUTE KIDNEY INJURY; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; DOXYCYCLINE; FEMALE; HUMANS; INDIA; INFANT; MALE; MYOCARDITIS; PROSPECTIVE STUDIES; SCRUB TYPHUS; SEX DISTRIBUTION;

EID: 84857116104     PISSN: 18760341     EISSN: 1876035X     Source Type: Journal    
DOI: 10.1016/j.jiph.2011.11.001     Document Type: Article

References (30)

1. Panpanich R., Garner P. Antibiotics for treating scrub typhus. Cochrane database Syst Rev 2002, 3:CD002150.
2. Huang C.T., Chi H., Lee H.C., Chiu N.C., Huang F.Y. Scrub typhus in children in a teaching hospital in eastern Taiwan, 2000-2005. Southeast Asian J Trop Med Public Health 2009, 40:789-794.
3. Sirisanthana V., Puthanakit T., Sirisanthana T. Epidemiologic, clinical and laboratory features of scrub typhus in thirty Thai children. Pediatr Infect Dis J 2003, 22:341-345.
4. Chanta C., Chanta S. Clinical study of 20 children with scrub typhus at Chiang Rai Regional Hospital. J Med Assoc Thai 2005, 88:1867-1872.
5. Silpapojakul K., Chupupakkarn S., Yuthasompob S., Varachit B., Chaipak D., Borkerd T., et al. Scrub and murine typhus in children with obscure fever in the tropics. Pediatr Infect Dis J 1991, 10:200-203.
6. Mahajan S.K., Rolain J.M., Sankhyan N., Kaushal R.K., Raoult D. Pediatric scrub typhus in Indian Himalayas. Indian J Pediatr 2008, 75:947-949.
7. Lee C.S., Min I.S., Hwang J.H., Kwon K.S., Lee H.B. Clinical significance of hypoalbuminemia in outcome of patients with scrub typhus. BMC Infect Dis 2010, 10:216-220.
8. Purcell K., Fergie J., Richman K., Rocha L. Murine typhus in children, South Texas. Emerg Infect Dis 2007, 13:926-927.
9. Zavala-Castro J.E., Zavala-Velazquez J.E., Uicab J.E.S. Murine typhus in child, Yucatan, Mexico. Emerg Infect Dis 2009, 15:972-974.
10. Vivekanandan M., Mani A., Priya Y.S., Singh A.P., Jayakumar S., Purty S. Outbreak of scrub typhus in Pondicherry. J Assoc Physicians India 2010, 58:24-28.
11. Sharma A., Mahajan S., Gupta M.L., Kanga A., Sharma V. Investigations of an outbreak of scrub typhus in the Himalayan Region of India. Jpn Infect Dis 2005, 58:208-210.
12. Razak A., Sathyanarayanan V., Prabhu M., Sangar M., Balasubramanian R. Scrub typhus in Southern India: are we doing enough. Trop Doct 2010, 40:149-151.
13. Chogle A.R. Diagnosis and treatment of scrub typhus-the Indian Scenario. J Assoc Physicians India 2010, 58:11-12.
14. Rathi N.B., Rathi A.N., Goodman M.H., Aghai Z.H. Rickettsial diseases in central India: proposed clinical scoring system for early detection of spotted fever. Indian Pediatr 2011, March 15 (Epub ahead of print).
15. Somashekar H.R., Moses P.D., Pavithran S., Mathew L.G., Agarwal I., Rolain J.M., et al. Magnitude and features of scrub typhus and spotted fever in children in India. J Trop Pediatr 2005, 16:228-229.
16. Murali N., Pillai S., Cherian T., Raghupathy P., Padmini V., Mathai E. Rickettsial infection in south India - how to spot the spotted fever. Indian Pediatr 2001, 38:1393-1396.
17. Digra S.K., Saini G.S., Singh V., Sharma S.D., Kaul R. Scrub typhus in children in children: Jammu experience. JK Science 2010, 12:95-97.
18. Pavithran S., Mathai E., Moses P.D. Scrub typhus. Indian Pediatr 2004, 41:1254-1257.
19. Joshi R., Punde A., Ohri A. Rickettsial infections seen in rural India. Bombay Hosp J 2009, 51:385-387.
20. Somu S., Desingh S.K. The eschar of scrub typhus. Indian J Pediatr 2010, August 19 (Epub ahead of print).
21. Mehta R.L., Kellum J.A., Shah S.V., Molitoris B.A., Ronco C., Warnock D.G., Levin A. Acute kidney injury network. Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11:R31.
22. Artigas A., Bernard G.R., Carle J. The American-European Consensus Conference on ARDS, part 2: ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med 1998, 157:1332.
23. Kamarasu K., Malathi M., Rajagopal V., Subramani K., Jagadeeshramasamy D., Mathai E. Serological evidence for wide distribution of spotted fevers & typhus fever in Tamil Nadu. Indian J Med Res 2007, 126:128-130.
24. Kulkarni A., Vaidya S., Kulkarni P., Bidri L.H., Padwal S. Rickettsial disease-an experience. Pediatr Infect Dis 2009, 1:118-124.
25. Sittiwangkul R., Pongprot Y., Silviliarat S., Oberdorfer P., Jittamala P., Sirisanthana V. Acute fulminant myocarditis in scrub typhus. Ann Trop Paediatr 2000, 28:149-154.
26. Yen T.H., Chang C.T., Lin J.L., Jiang J.R., Lee K.F. Scrub typhus: a frequently overlooked cause of acute renal failure. Ren Fail 2003, 25:397-410.
27. Lee S., Kang K.P., Kim W., Kang S.K., Lee H.B., Park S.K. A case of acute renal failure, rhabdomyolysis and disseminated intravascular coagulation associated with scrub typhus. Clin Nephrol 2003, 60:59-61.
28. Kim D.M., Kang D.W., Kim J.O., Chung J.H., Kim H.L., Park C.Y., et al. Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi. J Clin Microbiol 2008, 46:1548-1550.
29. Rathi N., Rathi A. Rickettsial infections: Indian perspective. Indian Pediatr 2010, 47:157-164.
30. Wu K.M., Wu Z.W., Peng G.Q., Wu J.L., Lee S.Y. Radiologic pulmonary findings, clinical manifestations and serious complications in scrub typhus: experiences from a teaching hospital in eastern Taiwan. Int J Gerontol 2009, 3:223-232.