Platelet function after cessation of chronic clopidogrel therapy

American Surgeon

Volumn 78, Issue 1, 2012, Pages 51-56

  Perakis, Peter G ^a   Yunus, Tahir ^a   Long, Graham ^a   Cheema, Zulfiqar F ^a   Hammond, Robert ^a   Shanley, Charles J ^a  

^a WILLIAM BEAUMONT HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; PROTON PUMP INHIBITOR; PURINERGIC P2Y12 RECEPTOR;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; CHRONIC DRUG ADMINISTRATION; CLINICAL ARTICLE; CLINICAL DECISION MAKING; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; ELECTIVE SURGERY; FEMALE; HUMAN; HUMAN CELL; MALE; PATIENT MONITORING; PERIOPERATIVE PERIOD; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; TREATMENT DURATION;

AGED; BLOOD PLATELETS; DRUG MONITORING; FEMALE; HUMANS; MALE; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; PROSPECTIVE STUDIES; PROTON PUMP INHIBITORS; RISK FACTORS; TICLOPIDINE;

EID: 84857099371     PISSN: 00031348     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction-summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol 2002;40:1366-74.
2. Kapetanakis EI, Medlam DA, Boyce SW, et al. Clopidogrel administration prior to coronary artery bypass grafting surgery: the cardiologist's panacea or the surgeon's headache? Eur Heart J 2005;26:576-83. (Pubitemid 40461099)
3. Leong JY, Baker RA, Shah PJ, et al. Clopidogrel and bleeding after coronary artery bypass graft surgery. Ann Thorac Surg 2005; 80:928-33. (Pubitemid 41196786)
4. Fox KA, Mehta SR, Peters R, et al. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial. Circulation 2004;110:1202-8. (Pubitemid 39202333)
5. Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502. (Pubitemid 32758501)
6. Grujic D, Martin D. Perioperative clopidogrel is seven days enough? Am Surg 2009;75:909-13.
7. George JN. Platelets. Lancet 2000;355:1531-9. (Pubitemid 30237365)
8. Breet NJ, van Werkum JW, Bouman HJ, et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 2010;303:754-62; erratum JAMA 2011;305:2172-3.
9. Marcucci R, Gori AM, Paniccia R, et al. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: a 12-month follow-up. Circulation 2009;119:237-42.
10. Paniccia R, Antonucci E, Gori AM, et al. Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients. J Thromb Haemost 2007;5:1839-47. (Pubitemid 47288940)
11. van Werkum JW, van der Stelt CA, Seesing TH, et al. A head-to-head comparison between the VerifyNow P2Y12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention. J Thromb Haemost 2006;4: 2516-8. (Pubitemid 44575456)
12. Malinin A, PokovA, SwaimL, et al. Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel. Methods Find Exp Clin Pharmacol 2006;28:315-22. (Pubitemid 44047198)
13. Burger W, Chemnitius JM, Kneissl GD, et al. Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis. J Intern Med 2005; 257:399-414. (Pubitemid 40604544)
14. Dunn AS, Turpie AG. Perioperative management of patients receiving oral anticoagulants: a systematic review. Arch Intern Med 2003;163:901-8. (Pubitemid 36522737)
15. Smout J, Stansby G. Current practice in the use of anti-platelet agents in the peri-operative period by UK vascular surgeons. Ann R Coll Surg Engl 2003;85:97-101. (Pubitemid 36372237)
16. Joseph JJ, Pillai A, Bramley D. Clopidogrel in orthopaedic patients: a review of current practice in Scotland. Thromb J 2007; 5:6.
17. Oudit D, Soueid A, Ross G, et al. Perioperative management of patients on anti-platelets and anti-coagulants presenting for dermatological surgical procedures. A UK survey. Eur J Dermatol 2007;17:317-20. (Pubitemid 47051547)
18. Lee SY, Tang SJ, Rockey DC, et al. Managing anti-coagulation and antiplatelet medications in GI endoscopy: a survey comparing the East and the West. Gastrointest Endosc 2008;67: 1076-81.
19. Pritchard MG, Townend JN, Lester WA, et al. Management of patients taking antiplatelet or anticoagulant medication requiring invasive breast procedures: United Kingdom survey of radiologists' and surgeons' current practice. Clin Radiol 2008;63: 305-11.
20. Wolf PA, Clagett GP, Easton JD, et al. Preventing ischemic stroke in patients with prior stroke and transient ischemic attack: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke 1999;30:1991-4.
21. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002;324:71-86.
22. Bracey AW, Grigore AM, Nussmeier NA. Impact of platelet testing on presurgical screening and implications for cardiac and noncardiac surgical procedures. Am J Cardiol 2006; 98:25N-32N.
23. Neumann FJ, Gawaz M, Ott I, et al. Prospective evaluation of hemostatic predictors of subacute stent thrombosis after coronary Palmaz-Schatz stenting. JAm Coll Cardiol 1996; 27:15-21. (Pubitemid 26018915)
24. Mollmann H, Nef HM, Hamm CW. Clinical pharmacology: antiplatelet therapy during surgery. Heart 2010;96:986-91.
25. Gurbel PA, Tantry US. Clopidogrel resistance? Thromb Res 2007;120:311-21. (Pubitemid 46881255)
26. Lev EI, Patel RT, Maresh KJ, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol 2006;47:27-33. (Pubitemid 43005160)
27. Gurbel PA, Bliden KP, Hiatt BL, et al. Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003;107: 2908-13. (Pubitemid 36736631)
28. Nguyen TA, Diodati JG, Pharand C. Resistance to clopidogrel: a review of the evidence. J Am Coll Cardiol 2005;45:1157-64. (Pubitemid 40523131)
29. Müller I, Besta F, Schulz C, et al. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89:783-7. (Pubitemid 36603418)
30. Varenhorst C, James S, Erlinge D, et al. Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin. Am Heart J 2009;157:562.e1-9.
31. Lordkipanidze M, Pharand C, Nguyen TA, et al. Comparison of four tests to assess inhibition of platelet function by clopidogrel in stable coronary artery disease patients. Eur Heart J 2008; 29:2877-85.
32. Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009; 301:937-44.
33. Price MJ, Coleman JL, Steinhubl SR, et al. Onset of platelet inhibition after high-dose clopidogrel loading and standard daily therapy measured by a point-of-care assay in healthy volunteers. Am J Cardiol 2006;98:681-4. (Pubitemid 44233472)