Histone Deacetylase Inhibitors

Journal of Thoracic Oncology

Volumn 6, Issue 11, 2011, Pages S1808-S1809

  Ramalingam, Suresh S ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR;

ARTICLE; CHEMISTRY; CLINICAL TRIAL (TOPIC); HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM;

CARCINOMA, NON-SMALL-CELL LUNG; CLINICAL TRIALS AS TOPIC; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; LUNG NEOPLASMS;

MLCS; MLOWN;

EID: 84857083808     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/01.JTO.0000407567.37523.8c     Document Type: Article

References (7)

1. Marks, P, Rifkind, RA, Richon, VM, et al. Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 1 (2001), 194–202.
2. Ramalingam, SS, Maitland, ML, Frankel, P, et al. Carboplatin and Paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer. J Clin Oncol 28 (2010), 56–62.
3. Ramalingam, SS, Parise, RA, Ramanathan, RK, et al. Phase I and pharmacokinetic study of vorinostat, a histone deacetylase inhibitor, in combination with carboplatin and paclitaxel for advanced solid malignancies. Clin Cancer Res 13 (2007), 3605–3610.
4. Jotte, RM, Witta, SE, Spira, AI, et al. Molecular analysis identifies a subset of non-small cell lung cancer patients with differential sensitivity to histone deacetylase inhibitor/epidermal growth factor receptor tyrosine kinase treatment. J Thorac Oncol, 3, 2010, S559.
5. Baylin, SB, Belinsky, SA, Herman, JG, Aberrant methylation of gene promoters in cancer—concepts, misconcepts, and promise. J Natl Cancer Inst 92 (2000), 1460–1461.
6. Owonikoko, TK, Ramalingam, SS, Kanterewicz, B, et al. Vorinostat increases carboplatin and paclitaxel activity in non-small-cell lung cancer cells. Int J Cancer 126 (2010), 743–755.
7. Zhang, Y, Adachi, M, Zou, H, et al. Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation. Int J Radiat Oncol Biol Phys 65 (2006), 859–866.