-
1
-
-
0037531121
-
Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracilleucovorin: Interim results of a phase III trial
-
PMID:12775730
-
Rothenberg ML, Oza AM, Bigelow RH, Berlin JD, Marshall JL, Ramanathan RK, et al. Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracilleucovorin: interim results of a phase III trial. J Clin Oncol 2003; 21:2059-69; PMID:12775730; http://dx. doi.org/10.1200/JCO.2003. 11.126
-
(2003)
J Clin Oncol
, vol.21
, pp. 2059-2069
-
-
Rothenberg, M.L.1
Oza, A.M.2
Bigelow, R.H.3
Berlin, J.D.4
Marshall, J.L.5
Ramanathan, R.K.6
-
2
-
-
26244466645
-
Hepatic and extrahepatic colorectal metastases: When resectable, their localization does not matter, but their total number has a prognostic effect
-
PMID:16184442
-
Elias D, Liberale G, Vernerey D, Pocard M, Ducreux M, Boige V, et al. Hepatic and extrahepatic colorectal metastases: when resectable, their localization does not matter, but their total number has a prognostic effect. Ann Surg Oncol 2005; 12:900-9; PMID:16184442; http://dx.doi.org/10.1245/ASO. 2005.01.010
-
(2005)
Ann Surg Oncol
, vol.12
, pp. 900-909
-
-
Elias, D.1
Liberale, G.2
Vernerey, D.3
Pocard, M.4
Ducreux, M.5
Boige, V.6
-
3
-
-
13744251436
-
Systemic therapy for colorectal cancer
-
PMID: 15689586
-
Meyerhardt JA, Mayer RJ. Systemic therapy for colorectal cancer. N Engl J Med 2005; 352:476-87; PMID: 15689586; http://dx.doi.org/10.1056/NEJMra040958
-
(2005)
N Engl J Med
, vol.352
, pp. 476-487
-
-
Meyerhardt, J.A.1
Mayer, R.J.2
-
4
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
PMID: 9807986
-
Rougier P, Van Cutsem E, Bajetta E, Niderele N, Possinger K, Labianca R, et al. Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 1998; 352:1407-12; PMID: 9807986; http://dx.doi.org/10.1016/S0140- 6736(98) 03085-2
-
(1998)
Lancet
, vol.352
, pp. 1407-1412
-
-
Rougier, P.1
Van Cutsem, E.2
Bajetta, E.3
Niderele, N.4
Possinger, K.5
Labianca, R.6
-
5
-
-
0031431131
-
5-Fluorouracil (5-FU) continuous intravenous infusion compared with bolus administration. Final results of a randomised trial in metastatic colorectal cancer
-
PMID:9470834
-
Rougier P, Paillot B, LaPlanche A, Morvan F, Seitz JF, Rekacewicz C, et al. 5-Fluorouracil (5-FU) continuous intravenous infusion compared with bolus administration. Final results of a randomised trial in metastatic colorectal cancer. Eur J Cancer 1997; 33:1789-93; PMID:9470834; http://dx.doi.org/10.1016/ S0959- 8049(97)00175-5
-
(1997)
Eur J Cancer
, vol.33
, pp. 1789-1793
-
-
Rougier, P.1
Paillot, B.2
LaPlanche, A.3
Morvan, F.4
Seitz, J.F.5
Rekacewicz, C.6
-
6
-
-
18444408375
-
COX-2: A molecular target for colorectal cancer prevention
-
PMID:15837998
-
Brown JR, DuBois RN. COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 2005; 23:2840-55; PMID:15837998; http://dx.doi.org/10. 1200/JCO.2005.09.051
-
(2005)
J Clin Oncol
, vol.23
, pp. 2840-2855
-
-
Brown, J.R.1
DuBois, R.N.2
-
7
-
-
34047105383
-
NSAIDs and cancer prevention: Targets downstream of COX-2
-
PMID:17100552
-
Cha YI, DuBois RN. NSAIDs and cancer prevention: targets downstream of COX-2. Annu Rev Med 2007; 58:239-52; PMID:17100552; http://dx.doi.org/10. 1146/annurev.med.57.121304.131253
-
(2007)
Annu Rev Med
, vol.58
, pp. 239-252
-
-
Cha, Y.I.1
DuBois, R.N.2
-
8
-
-
33747028253
-
Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/ treatment of colorectal cancer
-
PMID:16859832
-
Chell S, Kaidi A, Williams AC, Paraskeva C. Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/ treatment of colorectal cancer. Biochim Biophys Acta 2006; 1766:104-19; PMID:16859832
-
(2006)
Biochim Biophys Acta
, vol.1766
, pp. 104-119
-
-
Chell, S.1
Kaidi, A.2
Williams, A.C.3
Paraskeva, C.4
-
9
-
-
34547194891
-
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells
-
PMID: 17631291
-
Cherukuri DP, Chen XB, Goulet AC, Young RN, Han Y, Heimark RL, et al. The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells. Exp Cell Res 2007; 313:2969-79; PMID: 17631291; http://dx.doi.org/10.1016/j.yexcr.2007.06. 004
-
(2007)
Exp Cell Res
, vol.313
, pp. 2969-2979
-
-
Cherukuri, D.P.1
Chen, X.B.2
Goulet, A.C.3
Young, R.N.4
Han, Y.5
Heimark, R.L.6
-
10
-
-
34248372427
-
Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells
-
PMID:17130837
-
Hawcroft G, Ko CW, Hull MA. Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells. Oncogene 2007; 26:3006-19; PMID:17130837; http://dx.doi. org/10.1038/sj.onc.1210113
-
(2007)
Oncogene
, vol.26
, pp. 3006-3019
-
-
Hawcroft, G.1
Ko, C.W.2
Hull, M.A.3
-
11
-
-
33645504781
-
Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence
-
PMID:16540660
-
Chell SD, Witherden IR, Dobson RR, Moorghen M, Hermann AA, Qualtrough D, et al. Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence. Cancer Res 2006; 66:3106-13; PMID:16540660; http://dx.doi.org/10.1158/0008-5472.CAN-05-3702
-
(2006)
Cancer Res
, vol.66
, pp. 3106-3113
-
-
Chell, S.D.1
Witherden, I.R.2
Dobson, R.R.3
Moorghen, M.4
Hermann, A.A.5
Qualtrough, D.6
-
12
-
-
77649179672
-
Eicosanoids and cancer
-
PMID:20168319
-
Wang D, Dubois RN. Eicosanoids and cancer. Nat Rev Cancer 2010; 10:181-93; PMID:20168319; http://dx. doi.org/10.1038/nrc2809
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 181-193
-
-
Wang, D.1
Dubois, R.N.2
-
13
-
-
33645527575
-
Prostaglandin e receptor EP4 antagonism inhibits breast cancer metastasis
-
PMID:16540639
-
Ma X, Kundu N, Rifat S, Walser T, Fulton AM. Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis. Cancer Res 2006; 66:2923- 7; PMID:16540639; http://dx.doi.org/10.1158/0008-5472.CAN-05-4348
-
(2006)
Cancer Res
, vol.66
, pp. 2923-2927
-
-
Ma, X.1
Kundu, N.2
Rifat, S.3
Walser, T.4
Fulton, A.M.5
-
14
-
-
29944434200
-
Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation
-
PMID:16391234
-
Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica- Krezel L, DuBois RN. Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes Dev 2006; 20:77-86; PMID:16391234; http://dx.doi.org/ 10.1101/gad.1374506
-
(2006)
Genes Dev
, vol.20
, pp. 77-86
-
-
Cha, Y.I.1
Kim, S.H.2
Sepich, D.3
Buchanan, F.G.4
Solnica- Krezel, L.5
DuBois, R.N.6
-
15
-
-
0035947586
-
Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
-
PMID:11278548
-
Sheng H, Shao J, Washington MK, DuBois RN. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001; 276: 18075-81; PMID:11278548; http://dx.doi.org/10. 1074/jbc.M009689200
-
(2001)
J Biol Chem
, vol.276
, pp. 18075-18081
-
-
Sheng, H.1
Shao, J.2
Washington, M.K.3
DuBois, R.N.4
-
16
-
-
35348994840
-
PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras- PI3K association and cAMP-dependent kinase A activation
-
PMID:17640974
-
Leone V, di Palma A, Ricchi P, Acquaviva F, Giannouli M, Di Prisco AM, et al. PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras- PI3K association and cAMP-dependent kinase A activation. Am J Physiol Gastrointest Liver Physiol 2007; 293:G673-81; PMID:17640974; http://dx.doi. org/10.1152/ajpgi.00584.2006
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
-
-
Leone, V.1
Di Palma, A.2
Ricchi, P.3
Acquaviva, F.4
Giannouli, M.5
Di Prisco, A.M.6
-
17
-
-
0036142927
-
Involvement of prostaglandin e receptor subtype EP(4) in colon carcinogenesis
-
PMID: 11782353
-
Mutoh M, Watanabe K, Kitamura T, Shoji Y, Takahashi M, Kawamori T, et al. Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis. Cancer Res 2002; 62:28-32; PMID: 11782353
-
(2002)
Cancer Res
, vol.62
, pp. 28-32
-
-
Mutoh, M.1
Watanabe, K.2
Kitamura, T.3
Shoji, Y.4
Takahashi, M.5
Kawamori, T.6
-
18
-
-
33750308463
-
Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism
-
PMID:17018624
-
Yang L, Huang Y, Porta R, Yanagisawa K, Gonzalez A, Segi E, et al. Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism. Cancer Res 2006; 66:9665- 72; PMID:17018624; http://dx.doi.org/10.1158/ 0008-5472.CAN-06-1271
-
(2006)
Cancer Res
, vol.66
, pp. 9665-9672
-
-
Yang, L.1
Huang, Y.2
Porta, R.3
Yanagisawa, K.4
Gonzalez, A.5
Segi, E.6
-
19
-
-
3142782285
-
Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation
-
PMID:15123663
-
Pozzi A, Yan X, Macias-Perez I, Wei S, Hata AN, Breyer RM, et al. Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. J Biol Chem 2004; 279:29797- 804; PMID:15123663; http://dx.doi.org/10.1074/jbc. M313989200
-
(2004)
J Biol Chem
, vol.279
, pp. 29797-29804
-
-
Pozzi, A.1
Yan, X.2
Macias-Perez, I.3
Wei, S.4
Hata, A.N.5
Breyer, R.M.6
-
20
-
-
33750370444
-
MicroRNA signatures in human cancers
-
PMID: 17060945
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6:857-66; PMID: 17060945; http://dx.doi.org/10.1038/nrc1997
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
21
-
-
4143142117
-
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
-
PMID:15284443
-
Calin GA, Liu CG, Sevignani C, Ferracin M, Felli N, Dumitru CD, et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 2004; 101:11755- 60; PMID:15284443; http://dx.doi.org/10.1073/pnas. 0404432101
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11755-11760
-
-
Calin, G.A.1
Liu, C.G.2
Sevignani, C.3
Ferracin, M.4
Felli, N.5
Dumitru, C.D.6
-
22
-
-
1642374097
-
Specificity of microRNA target selection in translational repression
-
PMID:15014042
-
Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev 2004; 18:504-11; PMID:15014042; http://dx.doi.org/10. 1101/gad.1184404
-
(2004)
Genes Dev
, vol.18
, pp. 504-511
-
-
Doench, J.G.1
Sharp, P.A.2
-
23
-
-
77951030494
-
Modulation of mismatch repair and genomic stability by miR-155
-
PMID:20351277
-
Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, et al. Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci USA 2010; 107:6982-7; PMID:20351277; http://dx.doi. org/10.1073/pnas. 1002472107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6982-6987
-
-
Valeri, N.1
Gasparini, P.2
Fabbri, M.3
Braconi, C.4
Veronese, A.5
Lovat, F.6
-
24
-
-
35448990125
-
MicroRNA regulation of cyclo-oxygenase- 2 during embryo implantation
-
PMID:17848513
-
Chakrabarty A, Tranguch S, Daikoku T, Jensen K, Furneaux H, Dey SK. MicroRNA regulation of cyclo-oxygenase- 2 during embryo implantation. Proc Natl Acad Sci USA 2007; 104:15144-9; PMID:17848513; http://dx.doi.org/10.1073/pnas. 0705917104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15144-15149
-
-
Chakrabarty, A.1
Tranguch, S.2
Daikoku, T.3
Jensen, K.4
Furneaux, H.5
Dey, S.K.6
-
25
-
-
71849094971
-
Changes in microRNA expression levels correlate with clinicopathological features and prognoses in endometrial serous adenocarcinomas
-
PMID:19891660
-
Hiroki E, Akahira J, Suzuki F, Nagase S, Ito K, Suzuki T, et al. Changes in microRNA expression levels correlate with clinicopathological features and prognoses in endometrial serous adenocarcinomas. Cancer Sci 2010; 101:241-9; PMID:19891660; http://dx.doi. org/10.1111/j.1349-7006.2009.01385.x
-
(2010)
Cancer Sci
, vol.101
, pp. 241-249
-
-
Hiroki, E.1
Akahira, J.2
Suzuki, F.3
Nagase, S.4
Ito, K.5
Suzuki, T.6
-
26
-
-
59149098054
-
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
-
PMID:19155302
-
Su H, Yang JR, Xu T, Huang J, Xu L, Yuan Y, et al. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 2009; 69:1135-42; PMID:19155302; http://dx.doi.org/ 10.1158/0008-5472.CAN-08-2886
-
(2009)
Cancer Res
, vol.69
, pp. 1135-1142
-
-
Su, H.1
Yang, J.R.2
Xu, T.3
Huang, J.4
Xu, L.5
Yuan, Y.6
-
27
-
-
58149239686
-
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
-
PMID:19008416
-
Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008; 322:1695-9; PMID:19008416; http://dx.doi.org/10.1126/ science.1165395
-
(2008)
Science
, vol.322
, pp. 1695-1699
-
-
Varambally, S.1
Cao, Q.2
Mani, R.S.3
Shankar, S.4
Wang, X.5
Ateeq, B.6
-
28
-
-
64049086575
-
MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells
-
PMID: 19133256
-
Strillacci A, Griffoni C, Sansone P, Paterini P, Piazzi G, Lazzarini G, et al. MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp Cell Res 2009; 315:1439-47; PMID: 19133256; http://dx.doi.org/10.1016/j.yexcr.2008.12. 010
-
(2009)
Exp Cell Res
, vol.315
, pp. 1439-1447
-
-
Strillacci, A.1
Griffoni, C.2
Sansone, P.3
Paterini, P.4
Piazzi, G.5
Lazzarini, G.6
-
29
-
-
78549254601
-
The induction of S100p expression by the Prostaglandin E (PGE)/EP4 receptor signaling pathway in colon cancer cells
-
PMID: 20890108
-
Chandramouli A, Mercado-Pimentel ME, Hutchinson A, Gibadulinova A, Olson ER, Dickinson S, et al. The induction of S100p expression by the Prostaglandin E (PGE)/EP4 receptor signaling pathway in colon cancer cells. Cancer Biol Ther 2010; 10:1056-66; PMID: 20890108; http://dx.doi.org/10.4161/cbt.10.10.13373
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 1056-1066
-
-
Chandramouli, A.1
Mercado-Pimentel, M.E.2
Hutchinson, A.3
Gibadulinova, A.4
Olson, E.R.5
Dickinson, S.6
-
30
-
-
68849107323
-
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells
-
PMID: 19662683
-
Alvarez-Díaz S, Valle N, Garcia JM, Pena C, Freije JM, Quesada V, et al. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. J Clin Invest 2009; 119:2343-58; PMID: 19662683; http://dx.doi.org/10.1172/JCI37205
-
(2009)
J Clin Invest
, vol.119
, pp. 2343-2358
-
-
Alvarez-Díaz, S.1
Valle, N.2
Garcia, J.M.3
Pena, C.4
Freije, J.M.5
Quesada, V.6
-
31
-
-
40749119349
-
Loss of the eukaryotic initiation factor 3f in pancreatic cancer
-
PMID:17918192
-
Doldan A, Chandramouli A, Shanas R, Bhattacharyya A, Cunningham JT, Nelosn MA, et al. Loss of the eukaryotic initiation factor 3f in pancreatic cancer. Mol Carcinog 2008; 47:235-44; PMID:17918192; http:// dx.doi.org/10.1002/mc.20379
-
(2008)
Mol Carcinog
, vol.47
, pp. 235-244
-
-
Doldan, A.1
Chandramouli, A.2
Shanas, R.3
Bhattacharyya, A.4
Cunningham, J.T.5
Nelosn, M.A.6
-
32
-
-
55449098072
-
Chick embryo chorioallantoic membrane models to quantify angio-genesis induced by inflammatory and tumor cells or purified effector molecules
-
Chapter 2. PMID:19007659
-
Deryugina EI, Quigley JP. Chapter 2. Chick embryo chorioallantoic membrane models to quantify angio-genesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol 2008; 444:21-41; PMID:19007659; http://dx.doi.org/10. 1016/S0076-6879(08)02802-4
-
(2008)
Methods Enzymol
, vol.444
, pp. 21-41
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
33
-
-
56749097952
-
Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis
-
PMID:19005674
-
Deryugina EI, Quigley JP. Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochem Cell Biol 2008; 130:1119-30; PMID:19005674; http://dx.doi. org/10.1007/s00418-008-0536-2
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 1119-1130
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
34
-
-
34250330771
-
EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality
-
PMID:17290397
-
Gustafsson A, Hansson E, Kressner U, Nordgren S, Andersson M, Wang W, et al. EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality. Int J Cancer 2007; 121:232-40; PMID:17290397; http:// dx.doi.org/10.1002/ijc.22582
-
(2007)
Int J Cancer
, vol.121
, pp. 232-240
-
-
Gustafsson, A.1
Hansson, E.2
Kressner, U.3
Nordgren, S.4
Andersson, M.5
Wang, W.6
-
35
-
-
0037364161
-
The development of COX2 inhibitors
-
PMID:12612644
-
Flower RJ. The development of COX2 inhibitors. Nat Rev Drug Discov 2003; 2:179-91; PMID:12612644; http://dx.doi.org/10.1038/nrd1034
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 179-191
-
-
Flower, R.J.1
-
36
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
VIGOR Study Group. PMID:11087881
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos- Vargas R, Davis B, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000; 343:1520-8; PMID:11087881; http://dx.doi.org/10.1056/NEJM200011233432103
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos- Vargas, R.5
Davis, B.6
-
37
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
PMID:15713944
-
Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R. Finn, Pet al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005; 352: 1071-80; PMID:15713944; http://dx.doi.org/10. 1056/NEJMoa050405
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
-
38
-
-
36348932768
-
COX-2 inhibitors and cardiovascular risk
-
PMID:18030055
-
Funk CD, FitzGerald GA. COX-2 inhibitors and cardiovascular risk. J Cardiovasc Pharmacol 2007; 50: 470-9; PMID:18030055; http://dx.doi.org/10.1097/ FJC.0b013e318157f72d
-
(2007)
J Cardiovasc Pharmacol
, vol.50
, pp. 470-479
-
-
Funk, C.D.1
FitzGerald, G.A.2
-
39
-
-
77953497434
-
Scalable synthesis of a prostaglandin EP4 receptor antagonist
-
PMID:20469914
-
Gauvreau D, Dolman SJ, Hughes G, O'Shea PD, Davies IW. Scalable synthesis of a prostaglandin EP4 receptor antagonist. J Org Chem 2010; 75:4078-85; PMID:20469914; http://dx.doi.org/10.1021/jo1004197
-
(2010)
J Org Chem
, vol.75
, pp. 4078-4085
-
-
Gauvreau, D.1
Dolman, S.J.2
Hughes, G.3
O'Shea, P.D.4
Davies, I.W.5
-
40
-
-
78751643411
-
Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor
-
PMID:21215624
-
Burch JD, Farand J, Colucci J, Sturino C, Ducharme Y, Friesen RW, et al. Naphthalene/quinoline amides and sulfonylureas as potent and selective antagonists of the EP4 receptor. Bioorg Med Chem Lett 2011; 21:1041- 6; PMID:21215624; http://dx.doi.org/10.1016/j.bmcl. 2010.12.014
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 1041-1046
-
-
Burch, J.D.1
Farand, J.2
Colucci, J.3
Sturino, C.4
Ducharme, Y.5
Friesen, R.W.6
-
41
-
-
78651247521
-
The identification of substituted benzothiophene derivatives as PGE(2) subtype 4 receptor antagonists: From acid to non-acid
-
PMID:21208803
-
Li L, Mathieu MC, Denis D, Therien AG, Wang Z. The identification of substituted benzothiophene derivatives as PGE(2) subtype 4 receptor antagonists: From acid to non-acid. Bioorg Med Chem Lett 2011; 21:734-7; PMID:21208803; http://dx.doi.org/10. 1016/j.bmcl.2010.11.118
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 734-737
-
-
Li, L.1
Mathieu, M.C.2
Denis, D.3
Therien, A.G.4
Wang, Z.5
-
42
-
-
77951692935
-
A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models
-
PMID:20423341
-
Chen Q, Muramoto K, Masaaki N, Ding Y, Yang H, Mackey M, et al. A novel antagonist of the prostaglandin E(2) EP(4) receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models. Br J Pharmacol 2010; 160:292-310; PMID:20423341; http://dx.doi.org/10.1111/j.1476- 5381.2010.00647.x
-
(2010)
Br J Pharmacol
, vol.160
, pp. 292-310
-
-
Chen, Q.1
Muramoto, K.2
Masaaki, N.3
Ding, Y.4
Yang, H.5
Mackey, M.6
-
43
-
-
79551541972
-
Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2
-
PMID:21297974
-
Smits M, Mir SE, Nilsson RJ, van der Stoop PM, Niers JM, Marquez VE, Cloos J, et al. Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. PLoS ONE 2011; 6:e16282; PMID:21297974; http://dx. doi.org/10.1371/journal.pone.0016282
-
(2011)
PLoS ONE
, vol.6
-
-
Smits, M.1
Mir, S.E.2
Nilsson, R.J.3
Van Der Stoop, P.M.4
Niers, J.M.5
Marquez, V.E.6
Cloos, J.7
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