-
1
-
-
0142063079
-
Polygenic Inheritance of Breast Cancer: Implications for Design of Association Studies
-
DOI 10.1002/gepi.10261
-
Antoniou AC, Easton DF. Polygenic inheritance of breast cancer: implications for design of association studies. Genet Epidemiol 2003; 25:190-202. (Pubitemid 37296594)
-
(2003)
Genetic Epidemiology
, vol.25
, Issue.3
, pp. 190-202
-
-
Antoniou, A.C.1
Easton, D.F.2
-
2
-
-
0031014587
-
A note on the estimation of relative risks of rare genetic susceptibility markers
-
Begg CB, Berwick M. A note on the estimation of relative risks of rare genetic susceptibility markers. Cancer Epidemiol Biomarkers Prev 1997;6:99-103. (Pubitemid 27069202)
-
(1997)
Cancer Epidemiology Biomarkers and Prevention
, vol.6
, Issue.2
, pp. 99-103
-
-
Begg, C.B.1
Berwick, M.2
-
3
-
-
33746491583
-
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
-
DOI 10.1038/ng1837, PII NG1837
-
Renwick A, Thompson D, Seal S, Kelly P, Chagtai T, Ahmed M, et al. ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles. Nat Genet 2006;38:873-5. (Pubitemid 44141653)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
Kelly, P.4
Chagtai, T.5
Ahmed, M.6
North, B.7
Jayatilake, H.8
Barfoot, R.9
Spanova, K.10
McGuffog, L.11
Evans, D.G.12
Eccles, D.13
Easton, D.F.14
Stratton, M.R.15
Rahman, N.16
-
4
-
-
27544515629
-
Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: A familial study
-
DOI 10.1016/S0140-6736(05)67627-1, PII S0140673605676271
-
Johnson N, Fletcher O, Naceur-Lombardelli C, dos Santos Silva I, Ashworth A, Peto J. Interaction between CHEK21100delC and other low-penetrance breast-cancer susceptibility genes: a familial study. Lancet 2005;366:1554-7. (Pubitemid 41540113)
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1554-1557
-
-
Johnson, N.1
Fletcher, O.2
Naceur-Lombardelli, C.3
Dos, S.S.I.4
Ashworth, A.5
Peto, J.6
-
5
-
-
79952329937
-
Novel breast cancer susceptibility locus at 9q31.2: Results of a genome-wide association study
-
Fletcher O, Johnson N, Orr N, Hosking FJ, Gibson LJ, Walker K, et al. Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. J Natl Cancer Inst 2011;103: 425-35.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 425-435
-
-
Fletcher, O.1
Johnson, N.2
Orr, N.3
Hosking, F.J.4
Gibson, L.J.5
Walker, K.6
-
6
-
-
77952887426
-
Genome-wide association study identifies five new breast cancer susceptibility loci
-
Turnbull C, Ahmed S, Morrison J, Pernet D, Renwick A, Maranian M, et al. Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet 2010;42:504-7.
-
(2010)
Nat Genet
, vol.42
, pp. 504-507
-
-
Turnbull, C.1
Ahmed, S.2
Morrison, J.3
Pernet, D.4
Renwick, A.5
Maranian, M.6
-
7
-
-
34047100384
-
Constraints for genetic association studies imposed by attributable fraction and familial risk
-
DOI 10.1093/carcin/bgl182
-
Hemminki K, Bermejo JL. Constraints for genetic association studies imposed by attributable fraction and familial risk. Carcinogenesis 2007;28:648-56. (Pubitemid 46523360)
-
(2007)
Carcinogenesis
, vol.28
, Issue.3
, pp. 648-656
-
-
Hemminki, K.1
Bermejo, J.L.2
-
8
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-53.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
-
9
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
DOI 10.1086/321272
-
Pritchard JK. Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 2001;69:124-37. (Pubitemid 32614025)
-
(2001)
American Journal of Human Genetics
, vol.69
, Issue.1
, pp. 124-137
-
-
Pritchard, J.K.1
-
10
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
Dickson SP, Wang K, Krantz I, Hakonarson H, Goldstein DB. Rare variants create synthetic genome-wide associations. PLoS Biol 2010;8:e1000294.
-
(2010)
PLoS Biol
, vol.8
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
Hakonarson, H.4
Goldstein, D.B.5
-
11
-
-
79851468862
-
Synthetic associations are unlikely to account for many common disease genome-wide association signals
-
Anderson CA, Soranzo N, Zeggini E, Barrett JC. Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol 2011;9:e1000580.
-
(2011)
PLoS Biol
, vol.9
-
-
Anderson, C.A.1
Soranzo, N.2
Zeggini, E.3
Barrett, J.C.4
-
12
-
-
79851487367
-
Synthetic associations created by rare variants do not explain most GWAS results
-
Wray NR, Purcell SM, Visscher PM. Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol 2011;9: e1000579.
-
(2011)
PLoS Biol
, vol.9
-
-
Wray, N.R.1
Purcell, S.M.2
Visscher, P.M.3
-
13
-
-
79953738130
-
Quantifying the underestimation of relative risks from genome-wide association studies
-
Spencer C, Hechter E, Vukcevic D, Donnelly P. Quantifying the underestimation of relative risks from genome-wide association studies. PLoS Genet 2011;7:e1001337.
-
(2011)
PLoS Genet
, vol.7
-
-
Spencer, C.1
Hechter, E.2
Vukcevic, D.3
Donnelly, P.4
-
14
-
-
67650825015
-
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042
-
Milne RL, Benitez J, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, et al. Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst 2009;101: 1012-8.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1012-1018
-
-
Milne, R.L.1
Benitez, J.2
Nevanlinna, H.3
Heikkinen, T.4
Aittomaki, K.5
Blomqvist, C.6
-
15
-
-
67349237973
-
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2
-
Ahmed S, Thomas G, Ghoussaini M, Healey CS, Humphreys MK, Platte R, et al. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet 2009;41: 585-90.
-
(2009)
Nat Genet
, vol.41
, pp. 585-590
-
-
Ahmed, S.1
Thomas, G.2
Ghoussaini, M.3
Healey, C.S.4
Humphreys, M.K.5
Platte, R.6
-
16
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007;447: 1087-93.
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.4
Thompson, D.5
Ballinger, D.G.6
-
17
-
-
34250002140
-
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
-
DOI 10.1038/ng2064, PII NG2064
-
Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson SA, et al. Commonvariants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007;39:865-9. (Pubitemid 47014497)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 865-869
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Rafnar, T.4
Gudmundsson, J.5
Gudjonsson, S.A.6
Masson, G.7
Jakobsdottir, M.8
Thorlacius, S.9
Helgason, A.10
Aben, K.K.11
Strobbe, L.J.12
Albers-Akkers, M.T.13
Swinkels, D.W.14
Henderson, B.E.15
Kolonel, L.N.16
Le, M.L.17
Millastre, E.18
Andres, R.19
Godino, J.20
Garcia-Prats, M.D.21
Polo, E.22
Tres, A.23
Mouy, M.24
Saemundsdottir, J.25
Backman, V.M.26
Gudmundsson, L.27
Kristjansson, K.28
Bergthorsson, J.T.29
Kostic, J.30
Frigge, M.L.31
Geller, F.32
Gudbjartsson, D.33
Sigurdsson, H.34
Jonsdottir, T.35
Hrafnkelsson, J.36
Johannsson, J.37
Sveinsson, T.38
Myrdal, G.39
Grimsson, H.N.40
Jonsson, T.41
Von Holst, S.42
Werelius, B.43
Margolin, S.44
Lindblom, A.45
Mayordomo, J.I.46
Haiman, C.A.47
Kiemeney, L.A.48
Johannsson, O.T.49
Gulcher, J.R.50
Thorsteinsdottir, U.51
Kong, A.52
Stefansson, K.53
more..
-
18
-
-
61349163553
-
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1
-
Zheng W, Long J, Gao YT, Li C, Zheng Y, Xiang YB, et al. Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet 2009;41:324-8.
-
(2009)
Nat Genet
, vol.41
, pp. 324-328
-
-
Zheng, W.1
Long, J.2
Gao, Y.T.3
Li, C.4
Zheng, Y.5
Xiang, Y.B.6
-
19
-
-
67349158067
-
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)
-
Thomas G, Jacobs KB, Kraft P, Yeager M, Wacholder S, Cox DG, et al. A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet 2009;41:579-84.
-
(2009)
Nat Genet
, vol.41
, pp. 579-584
-
-
Thomas, G.1
Jacobs, K.B.2
Kraft, P.3
Yeager, M.4
Wacholder, S.5
Cox, D.G.6
-
20
-
-
79959569855
-
Disease model distortion in association studies
-
doi: 10.1002/ gepi.20576. [Epub ahead of print]
-
Vukcevic D, Hechter E, Spencer C, Donnelly P. Disease model distortion in association studies. Genet Epidemiol 2011; doi: 10.1002/ gepi.20576. [Epub ahead of print].
-
(2011)
Genet Epidemiol
-
-
Vukcevic, D.1
Hechter, E.2
Spencer, C.3
Donnelly, P.4
-
21
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium
-
International HapMap Consortium. A haplotype map of the human genome. Nature 2005;437:1299-320.
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
22
-
-
40149111451
-
What can genome-wide association studies tell us about the genetics of common disease?
-
Iles MM. What can genome-wide association studies tell us about the genetics of common disease? PLoS Genet 2008;4:e33.
-
(2008)
PLoS Genet
, vol.4
-
-
Iles, M.M.1
-
23
-
-
0036578764
-
Polygenic susceptibility to breast cancer and implications for prevention
-
Pharoah PD, Antoniou A, Bobrow M, Zimmern RL, Easton DF, Ponder BA. Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 2002;31:33-6.
-
(2002)
Nat Genet
, vol.31
, pp. 33-36
-
-
Pharoah, P.D.1
Antoniou, A.2
Bobrow, M.3
Zimmern, R.L.4
Easton, D.F.5
Ponder, B.A.6
|