Cytarabine induced cerebellar neuronal damage in juvenile rat: Correlating neurobehavioral performance with cellular and genetic alterations

Toxicology

Volumn 293, Issue 1-3, 2012, Pages 41-52

  Patel, Ronak S ^a   Rachamalla, Mahesh ^a   Chary, Namoju R ^a   Shera, Firdos Y ^a   Tikoo, Kulbhushan ^a   Jena, Gopabandhu ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Apoptosis; Ara C; Calbindin; Cerebellum; Histone acetylation; Purkinje cell

Indexed keywords

CALBINDIN; CASPASE 3; CYTARABINE; DNA; GLUTATHIONE; MALONALDEHYDE; PROTEIN P53; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; BRAIN FUNCTION; BRAIN INJURY; CELL DAMAGE; CEREBELLAR NEURONAL DAMAGE; CHROMOSOME ABERRATION; COGNITION; CONTROLLED STUDY; DNA DAMAGE; FLUID INTAKE; FOOD INTAKE; HISTONE ACETYLATION; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; METHYLATION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURKINJE CELL; RAT; WESTERN BLOTTING;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BEHAVIOR, ANIMAL; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CASPASE 3; CEREBELLUM; CYTARABINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTONES; MALE; NERVE TISSUE PROTEINS; NEUROTOXICITY SYNDROMES; ORGAN SIZE; OXIDATIVE STRESS; PSYCHOMOTOR PERFORMANCE; PURKINJE CELLS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEIN P53;

ARA; RATTUS;

EID: 84857063422     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.12.005     Document Type: Article

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