Intracellular concentrations of micafungin in different cellular compartments of the peripheral blood

International Journal of Antimicrobial Agents

Volumn 39, Issue 3, 2012, Pages 228-231

  Farowski, Fedja ^a   Cornely, Oliver A ^a,b,c   Vehreschild, Jörg J ^a   Bauer, Tim ^a   Hartmann, Pia ^a   Steinbach, Angela ^a   Vehreschild, Maria J G T ^a   Scheid, Christof ^a   Müller, Carsten ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c University of Cologne   (Germany)

Author keywords

Intracellular concentration; Peripheral blood mononuclear cells (PBMCs); Polymorphonuclear leukocytes (PMNs)

Indexed keywords

ALBUMIN; MICAFUNGIN;

ADULT; ALBUMIN BLOOD LEVEL; ARTICLE; BLOOD; CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG UPTAKE; ERYTHROCYTE; FEMALE; GERMANY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SPACE; LIQUID CHROMATOGRAPHY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; SYSTEMIC MYCOSIS; TANDEM MASS SPECTROMETRY;

ADULT; CHROMATOGRAPHY, LIQUID; ECHINOCANDINS; ERYTHROCYTES; FEMALE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPEPTIDES; MALE; MIDDLE AGED; MYCOSES; NEUTROPHILS; PLASMA; TANDEM MASS SPECTROMETRY;

EID: 84857056388     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2011.11.006     Document Type: Article

References (19)

1. G. Maschmeyer, A. Haas, and O.A. Cornely Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients Drugs 67 2007 1567 1601 (Pubitemid 47267298)
2. M.A. Pfaller, and D.J. Diekema Epidemiology of invasive candidiasis: a persistent public health problem Clin Microbiol Rev 20 2007 133 163 (Pubitemid 46167771)
3. P.G. Pappas, J.H. Rex, J. Lee, R.J. Hamill, R.A. Larsen, and W. Powderly A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients Clin Infect Dis 37 2003 634 643 (Pubitemid 37100802)
4. M.A. Pfaller, D.J. Diekema, L. Ostrosky-Zeichner, J.H. Rex, B.D. Alexander, and D. Andes Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints J Clin Microbiol 46 2008 2620 2629
5. Astellas. Mycamine. US Food and Drug Administration; 2005.
6. Merck. Cancidas. US Food and Drug Administration; 2001.
7. Pfizer. Eraxis. US Food and Drug Administration; 2006.
8. Astellas. Mycamine. European Medicines Agency; 2008.
9. Pfizer. Ecalta. European Medicines Agency; 2007.
10. J.A. Stone, S.D. Holland, P.J. Wickersham, A. Sterrett, M. Schwartz, and C. Bonfiglio Single- and multiple-dose pharmacokinetics of caspofungin in healthy men Antimicrob Agents Chemother 46 2002 739 745 (Pubitemid 34157659)
11. J.A. Dowell, W. Knebel, T. Ludden, M. Stogniew, D. Krause, and T. Henkel Population pharmacokinetic analysis of anidulafungin, an echinocandin antifungal J Clin Pharmacol 44 2004 590 598 (Pubitemid 38668021)
12. M.F. Hebert, H.E. Smith, T.C. Marbury, S.K. Swan, W.B. Smith, and R.W. Townsend Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction J Clin Pharmacol 45 2005 1145 1152 (Pubitemid 41361914)
13. T.J. Walsh, S. Goutelle, R.W. Jelliffe, J.A. Golden, E.A. Little, and C. DeVoe Intrapulmonary pharmacokinetics and pharmacodynamics of micafungin in adult lung transplant patients Antimicrob Agents Chemother 54 2010 3451 3459
14. F. Farowski, O.A. Cornely, J.J. Vehreschild, P. Hartmann, T. Bauer, and A. Steinbach Quantitation of azoles and echinocandins in compartments of peripheral blood by liquid chromatography-tandem mass spectrometry Antimicrob Agents Chemother 54 2010 1815 1819
15. J.R. Perfect, D.V. Savani, and D.T. Durack Uptake of itraconazole by alveolar macrophages Antimicrob Agents Chemother 37 1993 903 904 (Pubitemid 23096901)
16. F. Farowski, O.A. Cornely, J.J. Vehreschild, P. Hartmann, T. Bauer, and A. Steinbach Intracellular concentrations of posaconazole in different compartments of peripheral blood Antimicrob Agents Chemother 54 2010 2928 2931
17. K. Niimi, K. Maki, F. Ikeda, A.R. Holmes, E. Lamping, and M. Niimi Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility Antimicrob Agents Chemother 50 2006 1148 1155
18. P. Paderu, S. Park, and D.S. Perlin Caspofungin uptake is mediated by a high-affinity transporter in Candida albicans Antimicrob Agents Chemother 48 2004 3845 3849 (Pubitemid 39304613)
19. P. Paderu, G. Garcia-Effron, S. Balashov, G. Delmas, S. Park, and D.S. Perlin Serum differentially alters the antifungal properties of echinocandin drugs Antimicrob Agents Chemother 51 2007 2253 2256 (Pubitemid 46903131)