Skeletal remodeling following clinically relevant radiation-induced bone damage treated with zoledronic acid

Calcified Tissue International

Volumn 90, Issue 1, 2012, Pages 40-49

  Hui, Susanta K ^a   Fairchild, Gregory R ^a,b   Kidder, Louis S ^a   Sharma, Manju ^a   Bhattacharya, Maryka ^c   Jackson, Scott ^d   Le, Chap ^a   Yee, Douglas ^e  

^a UNIVERSITY OF MINNESOTA   (United States)

^b LAC+USC Medical Center   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Animal model; Bisphosphonate; Bone turnover; Bone turnover marker; Clinical radiation; Remodeling

Indexed keywords

CALCIUM 45; ZOLEDRONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE INJURY; BONE MINERAL; BONE REMODELING; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; FEMUR; ISOTOPE LABELING; LIQUID SCINTILLATION COUNTING; MORPHOMETRICS; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; STEADY STATE; TREATMENT OUTCOME;

ANIMALS; BONE AND BONES; BONE DENSITY CONSERVATION AGENTS; BONE REMODELING; CALCIUM ISOTOPES; DIPHOSPHONATES; FEMALE; FEMUR; IMIDAZOLES; MICE; MICE, INBRED BALB C; OSTEOCALCIN; RADIATION INJURIES, EXPERIMENTAL; TISSUE DISTRIBUTION;

EID: 84857047388     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-011-9547-4     Document Type: Article

References (29)

1. P Garnero N Buchs J Zekri R Rizzoli RE Coleman PD Delmas 2000 Markers of bone turnover for the management of patients with bone metastases from prostate cancer Br J Cancer 82 858 864 10732759 10.1054/bjoc.1999.1012 1:STN:280:DC%2BD3c7psVyqtQ%3D%3D (Pubitemid 30085239)
2. O Johnell A Oden C De Laet P Garnero P Delmas J Kanis 2002 Biochemical indices of bone turnover and the assessment of fracture probability Osteoporos Int 13 523 526 12111011 10.1007/s001980200068 1:STN:280:DC%2BD38zmslSntA%3D%3D (Pubitemid 34790623)
3. RP Heaney 2003 Is the paradigm shifting? Bone 33 457 465 14555248 10.1016/S8756-3282(03)00236-9 (Pubitemid 37222371)
4. E Seeman P Delmas 2006 Bone quality-the material and structural basis of bone strength and fragility N Engl J Med 354 2250 16723616 10.1056/NEJMra053077 1:CAS:528:DC%2BD28XkvVShsbw%3D
5. BJ Riis MA Hansen AM Jensen K Overgaard C Christiansen 1996 Low bone mass and fast rate of bone loss at menopause: equal risk factors for future fracture: a 15-year follow-up study Bone 19 9 12 8830981 10.1016/8756-3282(96) 00102-0 1:STN:280:DyaK28vislKltw%3D%3D (Pubitemid 26318738)
6. BL Riggs LJ Melton III 2002 Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density J Bone Miner Res 17 11 14 11771656 10.1359/jbmr.2002.17.1.11 (Pubitemid 33150991)
7. T Guise 2006 Bone loss and fracture risk associated with cancer therapy Oncologist 11 1121 1131 17110632 10.1634/theoncologist.11-10-1121 1:CAS:528:DC%2BD28XhtlCmu73L (Pubitemid 44788404)
8. N Baxter E Habermann J Tepper S Durham B Virnig 2005 Risk of pelvic fractures in older women following pelvic irradiation JAMA 294 2587 16304072 10.1001/jama.294.20.2587 1:CAS:528:DC%2BD2MXht1Kisb3J (Pubitemid 41697248)
9. W Small Jr L Kachnic 2005 Postradiotherapy pelvic fractures: cause for concern or opportunity for future research? JAMA 294 2635 16304079 10.1001/jama.294.20.2635 1:CAS:528:DC%2BD2MXht1Khsr3K (Pubitemid 41697255)
10. J Adams C Alsop E Harrison I Lernbass M Davies C Cann P Selby 2000 Quantitative computed tomography (QCT): The forgotten gold standard? J Bone Miner Res 15 1122 1123
11. T Keaveny D Kopperdahl L Melton III P Hoffmann S Amin B Riggs S Khosla 2010 Age-dependence of femoral strength in white women and men J Bone Miner Res 25 994 1001 19874201 10.1002/jbmr.231
12. Hui SK, Khalil A, Zhang Y, Coghill K, Le C, Dusenbery K, Froelich J, Yee D, Levi D (2010) Longitudinal assessment of bone loss from diagnostic CT scans in gynecologic cancer patients treated with chemotherapy and radiation. Am J Obstet Gynecol 203:353.e1-7
13. 41calcium as a new approach to assess changes in bone metabolism: effect of a bisphosphonate intervention in postmenopausal women with low bone mass J Bone Miner Res 22 1518 1525 17576167 10.1359/jbmr.070617 1:CAS:528:DC%2BD2sXhtFyhu7nL (Pubitemid 351229322)
14. 41Ca tracer Nucl Instrum Methods Phys Res B 259 796 800 10.1016/j.nimb.2007.02.003 1:CAS:528:DC%2BD2sXlsFKjtr8%3D (Pubitemid 46726830)
15. 41Ca as a long-term biological tracer for bone resorption Nucl Instr Methods 52 531 535 10.1016/0168-583X(90)90471-6
16. JR Green MJ Rogers 2002 Pharmacologic profile of zoledronic acid: a highly potent inhibitor of bone resorption Drug Dev Res 55 210 224 10.1002/ddr.10071 1:CAS:528:DC%2BD38Xlt1KqsLg%3D (Pubitemid 34774267)
17. L Knight C Kurbacher S Glaysher A Fernando R Reichelt S Dexel U Reinhold I Cree 2009 Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay BMC Cancer 9 38 19175937 10.1186/1471-2407-9-38
18. C Morgan PD Lewis RM Jones G Bertelli GA Thomas RCF Leonard 2007 The in vitro anti-tumour activity of zoledronic acid and docetaxel at clinically achievable concentrations in prostate cancer Acta Oncol 46 669 677 17562444 10.1080/02841860600996447 1:CAS:528:DC%2BD2sXmtlWms7s%3D (Pubitemid 46911908)
19. H Nyangoga S Blouin H Libouban MF Baslé D Chappard 2010 A single pretreatment by zoledronic acid converts metastases from osteolytic to osteoblastic in the rat Microsc Res Tech 73 733 740 19953666 1:CAS:528:DC%2BC3cXhtFCrurbK
20. J Fowler 2006 Development of radiobiology for oncology-a personal view Physics Med Biol 51 263 10.1088/0031-9155/51/13/R16 (Pubitemid 43958619)
21. C Ma 2000 AAPM TG-61 report on kilovoltage X-ray dosimetry: formalisms and applications IEEE Eng Med Biol Mag 3 2308 2312 (Pubitemid 32463239)
22. J Seuntjens 2000 AAPM TG-61 report on kilovoltage X-ray dosimetry. II. Calibration procedures and correction factors IEEE Eng Med Biol Mag 3 2313 2316 (Pubitemid 32463240)
23. S Pozzi S Vallet S Mukherjee D Cirstea N Vaghela L Santo E Rosen H Ikeda Y Okawa T Kiziltepe 2009 High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties Clin Cancer Res 15 5829 19737962 10.1158/1078-0432.CCR-09-0426 1:CAS:528:DC%2BD1MXhtFars73L
24. M Bouxsein S Boyd B Christiansen R Guldberg K Jepsen R Müller 2010 Guidelines for assessment of bone microstructure in rodents using microcomputed tomography J Bone Miner Res 25 1468 1486 20533309 10.1002/jbmr.141
25. 45Ca in nonpregnant mice on a calcium-deficient diet: evidence of direct effect of cadmium on bone Toxicol Appl Pharmacol 120 228 239 8511792 10.1006/taap.1993.1107 1:CAS:528:DyaK2cXitlOg (Pubitemid 23203327)
26. 45calcium kinetics against dynamic histomorphometry in a rat model to determine bone turnover Bone 46 1238 1243 20149909 10.1016/j.bone.2010.02.003 1:CAS:528:DC%2BC3cXksFClt74%3D
27. MN Weitzmann R Pacifici 2006 Estrogen deficiency and bone loss: an inflammatory tale J Clin Invest 116 1186 16670759 10.1172/JCI28550 1:CAS:528:DC%2BD28XksVWgu70%3D
28. S Gadeleta A Boskey E Paschalis C Carlson F Menschik T Baldini M Peterson C Rimnac 2000 A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (Macaca fascicularis) Bone 27 541 550 11033450 10.1016/S8756-3282(00)00362-8 1:CAS:528:DC%2BD3cXnt1Sjt78%3D
29. Y Bala D Farlay R Chapurlat G Boivin 2011 Modifications of bone material properties in postmenopausal osteoporotic women long-term treated with alendronate Eur J Endocrinol 165 647 655 21821631 10.1530/EJE-11-0333 1:CAS:528:DC%2BC3MXhsVSju7jM