Mapping discontinuous antibody epitopes to reveal protein structure and changes in structure related to function

Proceedings of the 2003 IEEE Bioinformatics Conference, CSB 2003

Volumn , Issue , 2003, Pages 585-586

  Mumey, B ^a   Angel, T ^b   Kirkpatrick, B ^a   Bailey, B ^c   Hargrave, P ^d   Jesaitis, A ^b   Dratz, E ^b  

^a Montana State University   (United States)

^b MONTANA STATE UNIVERSITY   (United States)

^c NIHNIAAA   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BIOINFORMATICS; CRYSTALLOGRAPHY; EPITOPES; PROTEINS; X RAY CRYSTALLOGRAPHY;

ANTIBODY BINDING SITES; PRIMARY SEQUENCES; PROTEIN STRUCTURES; STRUCTURE-RELATED; TARGET PROTEINS;

ANTIBODIES;

EID: 84857043317     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/CSB.2003.1227415     Document Type: Conference Paper

References (5)

1. Burritt, J., Busse, S., Gizachew, D., Siemsen, D., Quinn, M., Bond, C., Dratz, E., Jesaitis, A., "Antibody imprint of a membrane protein surface." Phagocyte flavocytochrome b, J. Biol. Chem.,273:24847-52.
2. Conte, L., Chothia, C., and Janin, J., "The atomic structure of protein-protein recognition sites." J. Mol. Biol., 285:2177-2198.
3. Mumey, B., Bailey, B., Dratz, E., "Revealing protein structure: A new method for mapping antibody epitopes." Proceedings of RECOMB 2002, Washington, DC.
4. Mumey, B., Bailey, B., Kirkpatrick, B., Jesaitis, A., Angel, T., Dratz, E., "A new method for mapping discontinuous antibody epitopes to reveal structural features of proteins." J. of Computational Biology, 10 (3-4), in press.
5. Padlan, E., "X-ray crystallography of antibodies." Adv. Protein Chemistry, 49:57-133