European neuroborreliosis: Neuropsychological findings 30months post-treatment

European Journal of Neurology

Volumn 19, Issue 3, 2012, Pages 480-487

  Eikeland, R ^a   Ljostad U ^b   Mygland, A ^b,c   Herlofson, K ^a   Lohaugen G C ^a,d  

^a Section for Gastroenterology   (Norway)

^b Sørlandet Hospital   (Norway)

^c UNIVERSITY OF BERGEN   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Cognition; Executive functions; Lyme disease; Lyme neuroborreliosis; Memory

Indexed keywords

ADULT; AGED; ARTICLE; ATTENTION; CASE CONTROL STUDY; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; FOLLOW UP; HUMAN; LEARNING TEST; LYME DISEASE; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGY; PRIORITY JOURNAL; PSYCHOLOGIC TEST; STROOP TEST; VERBAL MEMORY; VISUAL MEMORY;

ADULT; AGED; CASE-CONTROL STUDIES; COGNITION DISORDERS; EUROPE; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYME NEUROBORRELIOSIS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; YOUNG ADULT;

EID: 84857037294     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2011.03563.x     Document Type: Article

References (29)

1. Pachner AR, Steiner I. Lyme neuroborreliosis: infection, immunity, and inflammation. Lancet Neurol 2007; 6: 544-552.
2. Ljostad U, Mygland A. Remaining complaints 1year after treatment for acute Lyme neuroborreliosis; frequency, pattern and risk factors. Eur J Neurol 2009; 17: 118-123.
3. Eikeland R, Mygland A, Herlofson K, Ljøstad U. European neuroborreliosis: quality of life 30months after treatment. Acta Neurol Scand 2011; 124: 349-354.
4. Westervelt HJ, McCaffrey RJ. Neuropsychological functioning in chronic Lyme disease. Neuropsychol Rev 2002; 12: 153-177.
5. Wormser GP, Nadelman RB, Dattwyler RJ, et al. Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis 2000; 31(Suppl 1): 1-14.
6. McAuliffe P, Brassard MR, Fallon B. Memory and executive functions in adolescents with posttreatment Lyme disease. Appl Neuropsychol 2008; 15: 208-219.
7. Krupp LB, Masur D, Schwartz J, et al. Cognitive functioning in late Lyme borreliosis. Arch Neurol 1991; 48: 1125-1129.
8. Shadick NA, Phillips CB, Logigian EL, et al. The long-term clinical outcomes of Lyme disease. A population-based retrospective cohort study. Ann Intern Med 1994; 121: 560-567.
9. Kalish RA, Kaplan RF, Taylor E, Jones-Woodward L, Workman K, Steere AC. Evaluation of study patients with Lyme disease, 10-20-year follow-up. J Infect Dis 2001; 183: 453-460.
10. Keilp JG, Corbera K, Slavov I, Taylor MJ, Sackeim HA, Fallon BA. WAIS-III and WMS-III performance in chronic Lyme disease. J Int Neuropsychol Soc 2006; 12: 119-129.
11. Fallon BA, Keilp JG, Corbera KM, et al. A randomized, placebo-controlled trial of repeated IV antibiotic therapy for Lyme encephalopathy. Neurology 2008; 70: 992-1003.
12. Benke T, Gasse T, Hittmair-Delazer M, Schmutzhard E. Lyme encephalopathy: long-term neuropsychological deficits years after acute neuroborreliosis. Acta Neurol Scand 1995; 91: 353-357.
13. Ljøstad U, Skogvoll E, Eikeland R, et al. Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial. Lancet Neurol 2008; 7: 690-695.
14. Mygland A, Ljostad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 2010; 17: 8-14.
15. Kaplan RF, Trevino RP, Johnson GM, et al. Cognitive function in post-treatment Lyme disease: do additional antibiotics help? Neurology 2003; 60: 1916-1922.
16. Spreen O, Strauss E. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary, 3rd edn. New York: Oxford University Press, 2006: 477-479, 655-657, ISBN 0-19-515957-8.
17. Delis D, Kramer J, Kaplan E, Ober B. CVLT-II: California Verbal Learning Test-II. San Antonio, TX: The Psychological Corporation, 2000: 2-26, ISBN 015803573-9.
18. Kaplan RF. Neuropsychological aspects of Lyme disease. Appl Neuropsychol 1999; 6: 1-2.
19. Pollina DA, Elkins LE, Squires NK, Scheffer SR, Krupp LB. Does process-specific slowing account for cognitive deficits in Lyme disease? Appl Neuropsychol 1999; 6: 27-32.
20. Gaudino EA, Coyle PK, Krupp LB. Post-Lyme syndrome and chronic fatigue syndrome. Neuropsychiatric similarities and differences. Arch Neurol 1997; 54: 1372-1376.
21. Ravdin LD, Hilton E, Primeau M, Clements C, Barr WB. Memory functioning in Lyme borreliosis. J Clin Psychiatry 1996; 57: 282-286.
22. Rupprecht TA, Koedel U, Fingerle V, Pfister HW. The pathogenesis of lyme neuroborreliosis: from infection to inflammation. Mol Med 2008; 14: 205-212.
23. Fallon BA, Lipkin RB, Corbera KM, et al. Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy. Arch Gen Psychiatry 2009; 66: 554-563.
24. Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ. Regional cerebral blood flow and cognitive deficits in chronic lyme disease. J Neuropsychiatry Clin Neurosci 2003; 15: 326-332.
25. Krupp LB, Hyman LG, Grimson R, et al. Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial. Neurology 2002; 60: 1923-1930.
26. Klempner MS, Hu LT, Evans J, et al. Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease. N Engl J Med 2001; 345: 85-92.
27. Wilson RS, Rosenbaum G, Brown G, Rourke D, Whitman D, Grisell J. An index of premorbid intelligence. J Consult Clin Psychol 1978; 46: 1554-1555.
28. Bland JM, Altman DG. Multiple significance tests: the Bonferroni method. Br Med J 1995; 310: 170.
29. Pollina DA, Sliwinski M, Squires NK, Krupp LB. Cognitive processing speed in Lyme disease. Neuropsychiatry Neuropsychol Behav Neurol 1999; 12: 72-78.