Analysis of the interactions of viral and cellular factors with human cytomegalovirus lytic origin of replication, oriLyt

Virology

Volumn 424, Issue 2, 2012, Pages 106-114

  Kagele, Dominique ^a   Rossetto, Cyprian C ^a   Tarrant, Margaret T ^a   Pari, Gregory S ^a,b  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

HCMV; Lytic replication; OriLyt

Indexed keywords

BUB3 PROTEIN; CIS ACTING ELEMENT; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; IMMEDIATE EARLY PROTEIN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1; NUCLEOPHOSMIN; ORILYT; PROTEIN IE2; PROTEIN IRS1; PROTEIN UAP56; PROTEIN UL112; PROTEIN UL113; PROTEIN UL44; PROTEIN UL57; PROTEIN UL82; PROTEIN UL83; PROTEIN UL84; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA PURIFICATION; DNA REPLICATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE LOCUS; GENE PRODUCT; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

CELL CYCLE PROTEINS; CELL LINE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA REPLICATION; HOST-PATHOGEN INTERACTIONS; HUMANS; POLYPYRIMIDINE TRACT-BINDING PROTEIN; PROTEIN BINDING; REPLICATION ORIGIN; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 5;

EID: 84857035583     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.12.010     Document Type: Article

References (29)

1. Anders D.G., Kacica M.A., Pari G., Punturieri S.M. Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replication. J. Virol. 1992, 66(6):3373-3384.
2. Bomsztyk K., Denisenko O., Ostrowski J. hnRNP K: one protein multiple processes. Bioessays 2004, 26(6):629-638.
3. Colletti K.S., Xu Y., Cei S.A., Tarrant M., Pari G.S. Human cytomegalovirus UL84 oligomerization and heterodimerization domains act as transdominant inhibitors of oriLyt-dependent DNA replication: evidence that IE2-UL84 and UL84-UL84 interactions are required for lytic DNA replication. J. Virol. 2004, 78(17):9203-9214.
4. Colletti K.S., Smallenburg K.E., Xu Y., Pari G.S. Human cytomegalovirus UL84 interacts with an RNA stem-loop sequence found within the RNA/DNA hybrid region of oriLyt. J. Virol. 2007, 81(13):7077-7085.
5. Cristea I.M., Moorman N.J., Terhune S.S., Cuevas C.D., O'Keefe E.S., Rout M.P., Chait B.T., Shenk T. Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. J. Virol. 2010, 84(15):7803-7814.
6. Deng Z., Lezina L., Chen C.J., Shtivelband S., So W., Lieberman P.M. Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication. Mol. Cell 2002, 9(3):493-503.
7. DePamphilis M.L. Transcriptional elements as components of eukaryotic origins of DNA replication. Cell 1988, 52(5):635-638.
8. Gao Y., Colletti K., Pari G.S. Identification of human cytomegalovirus UL84 virus- and cell-encoded binding partners by using proteomics analysis. J. Virol. 2008, 82(1):96-104.
9. Gao Y., Kagele D., Smallenberg K., Pari G.S. Nucleocytoplasmic shuttling of human cytomegalovirus UL84 is essential for virus growth. J. Virol. 2010, 84(17):8484-8494.
10. Iskenderian A.C., Huang L., Reilly A., Stenberg R.M., Anders D.G. Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. J. Virol. 1996, 70(1):383-392.
11. Kagele D., Gao Y., Smallenburg K., Pari G.S. Interaction of HCMV UL84 with C/EBPalpha transcription factor binding sites within oriLyt is essential for lytic DNA replication. Virology 2009, 392(1):16-23.
12. Kim Y.E., Ahn J.H. Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus. J. Virol. 2010, 84(17):8409-8421.
13. Lischka P., Rauh C., Mueller R., Stamminger T. Human cytomegalovirus UL84 protein contains two nuclear export signals and shuttles between the nucleus and the cytoplasm. J. Virol. 2006, 80(20):10274-10280.
14. Marshall E.E., Bierle C.J., Brune W., Geballe A.P. Essential role for either TRS1 or IRS1 in human cytomegalovirus replication. J. Virol. 2009, 83(9):4112-4120.
15. Mikula M., Dzwonek A., Karczmarski J., Rubel T., Dadlez M., Wyrwicz L.S., Bomsztyk K., Ostrowski J. Landscape of the hnRNP K protein-protein interactome. Proteomics 2006, 6(8):2395-2406.
16. Pari G.S. Nuts and bolts of human cytomegalovirus lytic DNA replication. Curr. Top. Microbiol. Immunol. 2008, 325:153-166.
17. Pari G.S., Anders D.G. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication. J. Virol. 1993, 67(12):6979-6988.
18. Pari G.S., Anders D.G. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication. J. Virol. 1993, 67:6979-6988.
19. Pari G.S., Kacica M.A., Anders D.G. Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis. J. Virol. 1993, 67(5):2575-2582.
20. Rodems S.M., Clark C.L., Spector D.H. Separate DNA elements containing ATF/CREB and IE86 binding sites differentially regulate the human cytomegalovirus UL112-113 promoter at early and late times in the infection. J Virol 1998, 72(4):2697-2707.
21. Schmidt T., Striebinger H., Haas J., Bailer S.M. The heterogeneous nuclear ribonucleoprotein K is important for Herpes simplex virus-1 propagation. FEBS Lett. 2010, 584(20):4361-4365.
22. Schmolke S., Kern H.F., Drescher P., Jahn G., Plachter B. The dominant phosphoprotein pp 65 (UL83) of human cytomegalovirus is dispensable for growth in cell culture. J. Virol. 1995, 69:5959-5968.
23. Si H., Verma S.C., Robertson E.S. Proteomic analysis of the Kaposi's sarcoma-associated herpesvirus terminal repeat element binding proteins. J. Virol. 2006, 80(18):9017-9030.
24. Smith J.A., Pari G.S. Human cytomegalovirus UL102 gene. J. Virol. 1995, 69(3):1734-1740.
25. Strang B.L., Geballe A.P., Coen D.M. Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44. J. Gen. Virol. 2010, 91(Pt 9):2167-2175.
26. Verma S.C., Bajaj B.G., Cai Q., Si H., Seelhammer T., Robertson E.S. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virus. J. Virol. 2006, 80(22):11178-11190.
27. Wang Y., Li H., Tang Q., Maul G.G., Yuan Y. Kaposi's sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: involvement of host cellular factors. J. Virol. 2008, 82(6):2867-2882.
28. Xu Y., Cei S.A., Rodriguez Huete A., Colletti K.S., Pari G.S. Human cytomegalovirus DNA replication requires transcriptional activation via an IE2- and UL84-responsive bidirectional promoter element within oriLyt. J. Virol. 2004, 78(21):11664-11677.
29. Zhu Y., Huang L., Anders D.G. Human cytomegalovirus oriLyt sequence requirements. J. Virol. 1998, 72(6):4989-4996.