Molecular responses of choroidal endothelial cells to elastin derived peptides through the elastin-binding protein (GLB1)

Matrix Biology

Volumn 31, Issue 2, 2012, Pages 113-119

  Skeie, Jessica M ^a   Hernandez, Jasmine ^a   Hinek, Aleksander ^b   Mullins, Robert F ^a  

^a UNIVERSITY OF IOWA   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Bruch's membrane; Choroid; Elastin; Macula; Macular degeneration

Indexed keywords

BETA GALACTOSIDASE; COLLAGEN TYPE 4; ELASTIN; ELASTIN DERIVED PEPTIDE; MESSENGER RNA; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHOROID CAPILLARY LAYER; CHOROIDAL ENDOTHELIAL CELL; CONTROLLED STUDY; ELECTRORETINOGRAPHY; ENDOTHELIUM CELL; EYE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETINA; RETINA MACULA AGE RELATED DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY;

ALTERNATIVE SPLICING; ANIMALS; BETA-GALACTOSIDASE; BRUCH MEMBRANE; CATHEPSIN A; CELL LINE; CELL MIGRATION ASSAYS; CELL MOVEMENT; CHOROID; DIFFUSION; ELASTIN; ELECTRORETINOGRAPHY; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; NEOVASCULARIZATION, PATHOLOGIC; NEURAMINIDASE; PEPTIDES; PHENOTYPE; RETINA; RETINAL NEOVASCULARIZATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS;

EID: 84857032016     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2011.11.003     Document Type: Article

References (55)

1. Anderson D.H., Mullins R.F., Hageman G.S., Johnson L.V. A role for local inflammation in the formation of drusen in the aging eye. Am. J. Ophthalmol. 2002, 134:411-431.
2. Beattie J.R., Pawlak A.M., Boulton M.E., Zhang J., Monnier V.M., McGarvey J.J., Stitt A.W. Multiplex analysis of age-related protein and lipid modifications in human Bruch's membrane. FASEB J. 2010, 24:4816-4824.
3. Bhutto I.A., Uno K., Merges C., Zhang L., McLeod D.S., Lutty G.A. Reduction of endogenous angiogenesis inhibitors in Bruch's membrane of the submacular region in eyes with age-related macular degeneration. Arch. Ophthalmol. 2008, 126:670-678.
4. Bird A.C. Therapeutic targets in age-related macular disease. J. Clin. Invest. 2010, 120:3033-3041.
5. Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr. Opin. Cell Biol. 1995, 7:728-735.
6. Blumenkranz M.S., Russell S.R., Robey M.G., Kott-Blumenkranz R., Penneys N. Risk factors in age-related maculopathy complicated by choroidal neovascularization. Ophthalmology 1986, 93:552-558.
7. Booij J.C., Baas D.C., Beisekeeva J., Gorgels T.G., Bergen A.A. The dynamic nature of Bruch's membrane. Prog. Retin. Eye Res. 2010, 29:1-18.
8. Chen L., Miyamura N., Ninomiya Y., Handa J.T. Distribution of the collagen IV isoforms in human Bruch's membrane. Br. J. Ophthalmol. 2003, 87:212-215.
9. Chong N.H., Keonin J., Luthert P.J., Frennesson C.I., Weingeist D.M., Wolf R.L., Mullins R.F., Hageman G.S. Decreased thickness and integrity of the macular elastic layer of Bruch's membrane correspond to the distribution of lesions associated with age-related macular degeneration. Am. J. Pathol. 2005, 166:241-251.
10. Deshmane S.L., Kremlev S., Amini S., Sawaya B.E. Monocyte chemoattractant protein-1 (MCP-1): an overview. J. Interferon Cytokine Res. 2009, 29:313-326.
11. Duca L., Debelle L., Debret R., Antonicelli F., Hornebeck W., Haye B. The elastin peptides-mediated induction of pro-collagenase-1 production by human fibroblasts involves activation of MEK/ERK pathway via PKA- and PI(3)K-dependent signaling. FEBS Lett. 2002, 524:193-198.
12. Duca L., Floquet N., Alix A.J., Haye B., Debelle L. Elastin as a matrikine. Crit. Rev. Oncol. Hematol. 2004, 49:235-244.
13. Duca L., Blanchevoye C., Cantarelli B., Ghoneim C., Dedieu S., Delacoux F., Hornebeck W., Hinek A., Martiny L., Debelle L. The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J. Biol. Chem. 2007, 282:12484-12491.
14. Friedlander M., Theesfeld C.L., Sugita M., Fruttiger M., Thomas M.A., Chang S., Cheresh D.A. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:9764-9769.
15. Green W.R. Histopathology of age-related macular degeneration. Mol. Vis. 1999, 5:27.
16. Grossniklaus H.E., Green W.R. Histopathologic and ultrastructural findings of surgically excised choroidal neovascularization. Submacular Surgery Trials Research Group. Arch. Ophthalmol. 1998, 116:745-749.
17. Grossniklaus H.E., Martinez J.A., Brown V.B., Lambert H.M., Sternberg P., Capone A., Aaberg T.M., Lopez P.F. Immunohistochemical and histochemical properties of surgically excised subretinal neovascular membranes in age-related macular degeneration. Am. J. Ophthalmol. 1992, 114:464-472.
18. Hayden M.R., Sowers J.R., Tyagi S.C. The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded. Cardiovasc. Diabetol. 2005, 4:9.
19. Hinek A. Nature and the multiple functions of the 67-kD elastin-/laminin binding protein. Cell Adhes. Commun. 1994, 2:185-193.
20. Hinek A. Biological roles of the non-integrin elastin/laminin receptor. Biol. Chem. 1996, 377:471-480.
21. Hinek A., Rabinovitch M. 67-kD elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastin. J. Cell Biol. 1994, 126:563-574.
22. Hinek A., Rabinovitch M., Keeley F., Okamura-Oho Y., Callahan J. The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase. J. Clin. Invest. 1993, 91:1198-1205.
23. Imamura Y., Noda S., Hashizume K., Shinoda K., Yamaguchi M., Uchiyama S., Shimizu T., Mizushima Y., Shirasawa T., Tsubota K. Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:11282-11287.
24. Kinnunen K., Yl-Herttuala S. Vascular endothelial growth factors in retinal and choroidal neovascular diseases. Ann. Med. 2011, [Electronic publication ahead of print].
25. Makowska J.S., Grzegorczyk J., Cieslak M., Bienkiewicz B., Kowalski M.L. Recruitment of CD34+ progenitor cells into peripheral blood and asthma severity. Ann. Allergy Asthma Immunol. 2008, 101:402-406.
26. Malek G., Johnson L.V., Mace B.E., Saloupis P., Schmechel D.E., Rickman D.W., Toth C.A., Sullivan P.M., Bowes Rickman C. Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:11900-11905.
27. Marshall G.E., Konstas A.G., Reid G.G., Edwards J.G., Lee W.R. Collagens in the aged human macula. Graefes Arch. Clin. Exp. Ophthalmol. 1994, 232:133-140.
28. Mecham R.P., Hinek A., Griffin G.L., Senior R.M., Liotta L.A. The elastin receptor shows structural and functional similarities to the 67-kDa tumor cell laminin receptor. J. Biol. Chem. 1989, 264:16652-16657.
29. Mecham R.P., Whitehouse L., Hay M., Hinek A., Sheetz M.P. Ligand affinity of the 67-kD elastin/laminin binding protein is modulated by the protein's lectin domain: visualization of elastin/laminin-receptor complexes with gold-tagged ligands. J. Cell Biol. 1991, 113:187-194.
30. Mullins R.F., Skeie J.M., Malone E.A., Kuehn M.H. Macular and peripheral distribution of ICAM-1 in the human choriocapillaris and retina. Mol. Vis. 2006, 12:224-235.
31. Mullins R.F., Kuehn M.H., Faidley E.A., Syed N.A., Stone E.M. Differential macular and peripheral expression of bestrophin in human eyes and its implication for best disease. Investig. Ophthalmol. Vis. Sci. 2007, 48:3372-3380.
32. Nangia-Makker P., Baccarini S., Raz A. Carbohydrate-recognition and angiogenesis. Cancer Metastasis Rev. 2000, 19:51-57.
33. Pinto L.H., Invergo B., Shimomura K., Takahashi J.S., Troy J.B. Interpretation of the mouse electroretinogram. Doc. Ophthalmol. 2007, 115:127-136.
34. Privitera S., Prody C.A., Callahan J.W., Hinek A. The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J. Biol. Chem. 1998, 273:6319-6326.
35. Robinet A., Fahem A., Cauchard J.H., Huet E., Vincent L., Lorimier S., Antonicelli F., Soria C., Crepin M., Hornebeck W., Bellon G. Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP. J. Cell Sci. 2005, 118:343-356.
36. Robinet A., Millart H., Oszust F., Hornebeck W., Bellon G. Binding of elastin peptides to S-Gal protects the heart against ischemia/reperfusion injury by triggering the RISK pathway. FASEB J. 2007, 21:1968-1978.
37. Rodgers U.R., Weiss A.S. Integrin alpha v beta 3 binds a unique non-RGD site near the C-terminus of human tropoelastin. Biochimie 2004, 86:173-178.
38. Rodgers U.R., Weiss A.S. Cellular interactions with elastin. Pathol. Biol. (Paris) 2005, 53:390-398.
39. Saszik S.M., Robson J.G., Frishman L.J. The scotopic threshold response of the dark-adapted electroretinogram of the mouse. J. Physiol. 2002, 543:899-916.
40. Satz J.S., Philp A.R., Nguyen H., Kusano H., Lee J., Turk R., Riker M.J., Hernandez J., Weiss R.M., Anderson M.G., Mullins R.F., Moore S.A., Stone E.M., Campbell K.P. Visual impairment in the absence of dystroglycan. J. Neurosci. 2009, 29:13136-13146.
41. Scheetz T.E., Kim K.Y., Swiderski R.E., Philp A.R., Braun T.A., Knudtson K.L., Dorrance A.M., DiBona G.F., Huang J., Casavant T.L., Sheffield V.C., Stone E.M. Regulation of gene expression in the mammalian eye and its relevance to eye disease. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:14429-14434.
42. Seddon J.M., George S., Rosner B., Rifai N. Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch. Ophthalmol. 2005, 123:774-782.
43. Senior R.M., Griffin G.L., Mecham R.P., Wrenn D.S., Prasad K.U., Urry D.W. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J. Cell Biol. 1984, 99:870-874.
44. Senior R.M., Hinek A., Griffin G.L., Pipoly D.J., Crouch E.C., Mecham R.P. Neutrophils show chemotaxis to type IV collagen and its 7S domain and contain a 67kD type IV collagen binding protein with lectin properties. Am. J. Respir. Cell Mol. Biol. 1989, 1:479-487.
45. Sivaprasad S., Chong N.V., Bailey T.A. Serum elastin-derived peptides in age-related macular degeneration. Investig. Ophthalmol. Vis. Sci. 2005, 46:3046-3051.
46. Skeie J.M., Mullins R.F. Elastin-mediated choroidal endothelial cell migration: possible role in age-related macular degeneration. Investig. Ophthalmol. Vis. Sci. 2008, 49:5574-5580.
47. Spraul C.W., Lang G.E., Grossniklaus H.E., Lang G.K. Histologic and morphometric analysis of the choroid, Bruch's membrane, and retinal pigment epithelium in postmortem eyes with age-related macular degeneration and histologic examination of surgically excised choroidal neovascular membranes. Surv. Ophthalmol. 1999, 44(Suppl. 1):S10-S32.
48. Stone E.M. A very effective treatment for neovascular macular degeneration. N. Engl. J. Med. 2006, 355:1493-1495.
49. Van der Schaft T.L., de Bruijn W.C., Mooy C.M., de Jong P.T. Basal laminar deposit in the aging peripheral human retina. Graefes Arch. Clin. Exp. Ophthalmol. 1993, 231:470-475.
50. Van der Schaft T.L., Mooy C.M., de Bruijn W.C., Bosman F.T., de Jong P.T. Immunohistochemical light and electron microscopy of basal laminar deposit. Graefes Arch. Clin. Exp. Ophthalmol. 1994, 232:40-46.
51. Van Wijngaarden P., Coster D.J., Williams K.A. Inhibitors of ocular neovascularization: promises and potential problems. Jama 2005, 293:1509-1513.
52. Vine A.K., Stader J., Branham K., Musch D.C., Swaroop A. Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Ophthalmology 2005, 112:2076-2080.
53. Yu S.Y., Yoshida A. The fate of 14C-elastin in the peritoneal cavity of rats. I. Biochemical studies. Lab. Investig. 1977, 37:143-149.
54. Yu S.Y., Ruthmeyer S.K., Shepard J.W. Digestion and absorption of radioactive elastins in rats. Proc. Soc. Exp. Biol. Med. 1979, 161:239-243.
55. Yu H.G., Liu X., Kiss S., Connolly E., Gragoudas E.S., Michaud N., Bulgakov O., Adamian M., Deangelis M.M., Miller J.W., Li T., Kim I.K. Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1. Invest. Ophthalmol. Vis. Sci. 2008, 49(6):2599-2605.