The heart-specific NH 2-terminal extension regulates the molecular conformation and function of cardiac troponin I

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 4, 2012, Pages

  Akhter, Shirin ^a   Zhang, Zhiling ^a   Jin, J P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac muscle regulation; Protein conformation analysis; Proteolytic NH 2 terminal truncation; TnI TnT interface; Troponin i phosphorylation

Indexed keywords

CALCIUM ION; CARDIAC TROPONIN I; EPITOPE; MONOCLONAL ANTIBODY; TROPONIN C; TROPONIN I; UNCLASSIFIED DRUG; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPROTEIN; PEPTIDE FRAGMENT; TROPONIN T;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; GENE DELETION; MOUSE; NH2 TERMINAL EXTENSION; NONHUMAN; PKA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; ANIMAL; ANIMAL MODEL; CATTLE; CHEMISTRY; CONFORMATION; GENETICS; HEART; HEART CONTRACTION; HEART MUSCLE; HUMAN; METABOLISM; MUSCLE RELAXATION; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CATTLE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EPITOPES; GENE DELETION; HEART; HUMANS; MICE; MODELS, ANIMAL; MOLECULAR CONFORMATION; MUSCLE RELAXATION; MYOCARDIAL CONTRACTION; MYOCARDIUM; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN ISOFORMS; TROPONIN I; TROPONIN T;

EID: 84857027434     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00637.2011     Document Type: Article

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