Topiramate and the vision: A systematic review

Clinical Ophthalmology

Volumn 6, Issue 1, 2012, Pages 117-131

  Abtahi, Mohammad Ali ^a,b   Abtahi, Seyed Hossein ^a,b   Fazel, Farhad ^b   Roomizadeh, Peyman ^a   Etemadifar, Masoud ^a   Jenab, Keivan ^b   Akbari, Mojtaba ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Eye; Ophthalmology; Review; Side effect; Topiramate; Vision

Indexed keywords

ACETAZOLAMIDE; CORTICOSTEROID; CYCLOPLEGIC AGENT; MANNITOL; MEPREDNISONE; MIOTIC AGENT; PILOCARPINE; PREDNISOLONE; TOPIRAMATE;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; AGED; ALCOHOLISM; ALICE IN WONDERLAND SYNDROME; ARGON LASER; BLURRED VISION; CAUSAL ATTRIBUTION; CHILD; CHOROID DETACHMENT; CHOROID DISEASE; CHRONIC DRUG ADMINISTRATION; CILIOCHOROIDAL EFFUSION SYNDROME; CLOSED ANGLE GLAUCOMA; CONJUNCTIVITIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG HALF LIFE; DRUG INDICATION; DRUG SAFETY; DRUG WITHDRAWAL; EYE INFLAMMATION; FEMALE; GLAUCOMA; HEADACHE; HOMONYMOUS HEMIANOPIA; HUMAN; INTRAOCULAR PRESSURE ABNORMALITY; LOW DRUG DOSE; LOW LEVEL LASER THERAPY; MAJOR CLINICAL STUDY; MALE; MIGRAINE; MYDRIASIS; MYOPIA; NEUROLOGIC DISEASE; OBESITY; PAIN; RETINA DETACHMENT; RETINA MACULOPATHY; RETINOPATHY; REVIEW; RISK BENEFIT ANALYSIS; SCHOOL CHILD; SCLERA DISEASE; SCLERITIS; SEIZURE; SYSTEMATIC REVIEW; TRABECULECTOMY; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT; UVEITIS; VISUAL DISORDER; VISUAL FIELD DEFECT; VISUAL IMPAIRMENT;

EID: 84857006950     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: 10.2147/OPTH.S27695     Document Type: Review

References (100)

1. Angehagen M, Ronnback L, Hansson E, Ben-Menachem E. Topiramate reduces AMPA-induced Ca(2+) transients and inhibits GluR1 subunit phosphorylation in astrocytes from primary cultures. J Neurochem. 2005;94(4):1124-1130.
2. Panday VA, Rhee DJ. Review of sulfonamide-induced acute myopia and acute bilateral angle-closure glaucoma. Compr Ophthalmol Update. 2007;8(5):271-276.
3. Mirza NS, Alfirevic A, Jorgensen A, Marson AG, Pirmohamed M. Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors. Pharmacogenet Genomics. 2011;21(5): 297-302.
4. United States Food and Drug Administration; Ortho-McNeil Pharmaceutical Inc. FDA approved labeling text. 2011. Available from: www. fda.gov/downloads/Drugs/DrugSafety/UCM152837.pdf. Accessed August 27, 2011.
5. Christensen J, Hojskov CS, Dam M, Poulsen JH. Plasma concentration of topiramate correlates with cerebrospinal fluid concentration. Ther Drug Monit. 2001;23(5):529-535.
6. Perucca E. A pharmacological and clinical review on topiramate, a new antiepileptic drug. Pharmacol Res. 1997;35(4):241-256.
7. Lyseng-Williamson KA, Yang LP. Topiramate: a review of its use in the treatment of epilepsy. Drugs. 2007;67(15):2231-2256.
8. Ramadan NM, Buchanan TM. New and future migraine therapy. Pharmacol Ther. 2006;112(1):199-212.
9. Zou LP, Lin Q, Qin J, Cai FC, Liu ZS, Mix E. Evaluation of open-label topiramate as primary or adjunctive therapy in infantile spasms. Clin Neuropharmacol. 2008;31(2):86-92.
10. Mula M, Cavanna AE, Monaco F. Psychopharmacology of topiramate: from epilepsy to bipolar disorder. Neuropsychiatr Dis Treat. 2006;2(4):475-488.
11. Berlin HA. Antiepileptic drugs for the treatment of post-traumatic stress disorder. Curr Psychiatry Rep. 2007;9(4):291-300.
12. Supuran CT, Di Fiore A, De Simone G. Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity. Expert Opin Emerg Drugs. 2008;13(2):383-392.
13. Johnson BA, Ait-Daoud N. Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patients. Curr Pharm Des. 2010;16(19):2103-2112.
14. McElroy SL, Guerdjikova AI, Martens B, Keck PE Jr, Pope HG, Hudson JI. Role of antiepileptic drugs in the management of eating disorders. CNS Drugs. 2009;23(2):139-156.
15. Hollander E, Dell'Osso B. Topiramate plus paroxetine in treatmentresistant obsessive-compulsive disorder. Int Clin Psychopharmacol. 2006;21(3):189-191.
16. Celebisoy N, Gokcay F, Sirin H, Akyurekli O. Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study. Acta Neurol Scand. 2007;116(5):322-327.
17. Bendaly EA, Jordan CA, Staehler SS, Rushing DA. Topiramate in the treatment of neuropathic pain in patients with cancer. Support Cancer Ther. 2007;4(4):241-246.
18. Garcia Campayo J, Sobradiel N, Alda M, et al. Effectiveness of topiramate for tobacco dependence in patients with depression; a randomised, controlled trial. BMC Fam Pract. 2008;9:28.
19. Zalialova ZA, Latypova GR. Topiramate in the treatment of essential tremor. Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(11):39-42. Russian.
20. Fowler JA, Shen JY, Bettinger TL. Successful use of topiramate in a patient with severe postherpetic neuralgia. Ann Pharmacother. 2009; 43(1):139-142.
21. Lyon GJ, Shprecher D, Coffey B, Kurlan R. Tourette's Disorder. Curr Treat Options Neurol. 2010;12(4):274-286.
22. Wisniewski M, Lukasik-Glebocka M, Anand JS. Acute topiramate overdose-clinical manifestations. Clin Toxicol (Phila). 2009;47(4):317-320.
23. Fraunfelder FW, Fraunfelder FT, Keates EU. Topiramate-associated acute, bilateral, secondary angle-closure glaucoma. Ophthalmology. 2004;111(1):109-111.
24. Thambi L, Kapcala LP, Chambers W, et al. Topiramate-associated secondary angle-closure glaucoma: a case series. Arch Ophthalmol. 2002;120(8):1108.
25. Ozturk BT, Genc E, Tokgoz M, Kerimoglu H, Genc BO. Ocular changes associated with topiramate. Curr Eye Res. 2011;36(1):47-52.
26. Leung DY, Leung H, Baig N, et al. Topiramate and asymptomatic ocular angle narrowing: a prospective pilot study. Eye (Lond). 2009; 23(11):2079-2081.
27. Sills GJ, Butler E, Forrest G, Ratnaraj N, Patsalos PN, Brodie MJ. Vigabatrin, but not gabapentin or topiramate, produces concentrationrelated effects on enzymes and intermediates of the GABA shunt in rat brain and retina. Epilepsia. 2003;44(7):886-892.
28. Yoneda S, Tanaka E, Goto W, Ota T, Hara H. Topiramate reduces excitotoxic and ischemic injury in the rat retina. Brain Res. 2003;967(1-2): 257-266.
29. Kjellstrom S, Bruun A, Isaksson B, Eriksson T, Andreasson S, Ponjavic V. Retinal function and histopathology in rabbits treated with topiramate. Doc Ophthalmol. 2006;113(3):179-186.
30. Nampiaparampil DE, Nampiaparampil RG, Prasad AG. Topiramate for the treatment of chronic corneal pain. Cornea. 2008;27(1):124-126.
31. Anghelescu I, Klawe C, Himmerich H, Szegedi A. Topiramate in venlafaxine-induced visual hallucinations in an obese patient with a posterior cerebral artery infarction. J Clin Psychopharmacol. 2001; 21(4):462-464.
32. Gubbay SS. The occurrence of drug-induced myopia as a transient side effect of topiramate. Epilepsia. 1998;39(4):451.
33. Sen HA, O'Halloran HS, Lee WB. Case reports and small case series: topiramate-induced acute myopia and retinal striae. Arch Ophthalmol. 2001;119(5):775-777.
34. Banta JT, Hoffman K, Budenz DL, Ceballos E, Greenfield DS. Presumed topiramate-induced bilateral acute angle-closure glaucoma. Am J Ophthalmol. 2001;132(1):112-114.
35. Sankar PS, Pasquale LR, Grosskreutz CL. Uveal effusion and secondary angle-closure glaucoma associated with topiramate use. Arch Ophthalmol. 2001;119(8):1210-1211.
36. Rhee DJ, Goldberg MJ, Parrish RK. Bilateral angle-closure glaucoma and ciliary body swelling from topiramate. Arch Ophthalmol. 2001; 119(11):1721-1723.
37. Nemet A, Nesher R, Almog Y, Assia E. Bilateral acute angle closure glaucoma following topiramate treatment. Harefuah. 2002; 141(7):597-599, 667. Hebrew.
38. Zweifler RM, McKinley B, Duval D. Topiramate-induced myopia. Headache. 2002;42(1):85-86.
39. Foroozan R, Buono LM. Foggy visual field defect. Surv Ophthalmol. 2003;48(4):447-451.
40. Chen TC, Chao CW, Sorkin JA. Topiramate induced myopic shift and angle closure glaucoma. Br J Ophthalmol. 2003; 87(5):648-649.
41. Medeiros FA, Zhang XY, Bernd AS, Weinreb RN. Angle-closure glaucoma associated with ciliary body detachment in patients using topiramate. Arch Ophthalmol. 2003;121(2):282-285.
42. Lin J, Fosnot J, Edmond J. Bilateral angle closure glaucoma in a child receiving oral topiramate. J AAPOS. 2003;7(1):66-68.
43. Coats DK. Bilateral angle closure glaucoma in a child receiving oral topiramate. J AAPOS. 2003;7(4):303.
44. Boentert M, Aretz H, Ludemann P. Acute myopia and angle-closure glaucoma induced by topiramate. Neurology. 2003;61(9):1306.
45. Vaphiades MS, Mason J. Foggy visual field defect. Surv Ophthalmol. 2004;49(2):266-267.
46. Craig JE, Ong TJ, Louis DL, Wells JM. Mechanism of topiramateinduced acute-onset myopia and angle closure glaucoma. Am J Ophthalmol. 2004;137(1):193-195.
47. Bhattacharyya KB, Basu S. Acute myopia induced by topiramate: report of a case and review of the literature. Neurol India. 2005;53(1): 108-109.
48. Cereza G, Pedros C, Garcia N, Laporte JR. Topiramate in non-approved indications and acute myopia or angle closure glaucoma. Br J Clin Pharmacol. 2005;60(5):578-579.
49. Mansoor Q, Jain S. Bilateral angle-closure glaucoma following oral topiramate therapy. Acta Ophthalmol Scand. 2005;83(5):627-628.
50. Santmyire-Rosenberger BR, Albert M. Acquired trichomegaly with topiramate. J Am Acad Dermatol. 2005;53(2):362-363.
51. Desai CM, Ramchandani SJ, Bhopale SG, Ramchandani SS. Acute myopia and angle closure caused by topiramate, a drug used for prophylaxis of migraine. Indian J Ophthalmol. 2006;54(3):195-197.
52. Asensio-Sanchez VM, Torreblanca-Aguera B, Martinez-Calvo S, Calvo MJ, Rodriguez R. Severe ocular side effects with Topamax. Arch Soc Esp Oftalmol. 2006; 81(6):345-348. Spanish.
53. Levy J, Yagev R, Petrova A, Lifshitz T. Topiramate-induced bilateral angle-closure glaucoma. Can J Ophthalmol. 2006;41(2):221-225.
54. Rhee DJ, Ramos-Esteban JC, Nipper KS. Rapid resolution of topiramate-induced angle-closure glaucoma with methylprednisolone and mannitol. Am J Ophthalmol. 2006;141(6):1133-1134.
55. Sachi D, Vijaya L. Topiramate induced secondary angle closure glaucoma. J Postgrad Med. 2006;52(1):72-73.
56. Viet Tran H, Ravinet E, Schnyder C, Reichhart M, Guex-Crosier Y. Blood-brain barrier disruption associated with topiramate-induced angle-closure glaucoma of acute onset. Klin Monbl Augenheilkd. 2006; 223(5):425-427.
57. Evans RW. Reversible palinopsia and the Alice in Wonderland syndrome associated with topiramate use in migraineurs. Headache. 2006; 46(5):815-818.
58. Guier CP. Elevated intraocular pressure and myopic shift linked to topiramate use. Optom Vis Sci. 2007; 84(12):1070-1073.
59. Izambart C, Rocher F, Zur C, Chichmanian RM, Gastaud P. Topiramate and acute myopia with angle-closure glaucoma: case report and literature review. J Fr Ophtalmol. 2007;30(5):e11. French.
60. Palomares P, Amselem L, Diaz-Llopis M. Optical coherence tomography for diagnosis and monitoring of angle-closure glaucoma induced by topiramate. Can J Ophthalmol. 2007;42(4):633-634.
61. Parikh R, Parikh S, Das S, Thomas R. Choroidal drainage in the management of acute angle closure after topiramate toxicity. J Glaucoma. 2007;16(8):691-693.
62. Ponz de Tienda A, Gil-Gimeno R, Piera-Balbastre A, Salvador- Aliaga A, Chamarro-Lazaro R, Lainez-Andres JM. Topiramate and acute glaucoma. Rev Neurol. 2007; 44(12):766. Spanish.
63. Rodriguez-Gomez D, Castro-Perez A, Landaluce-Chaves ML, Cid- Rodriguez MC, Lustres-Perez M, Gomez-Fernandez RC. Narrow-angle glaucoma and acute myopia from using topiramate as prophylactic treatment of migraine. Rev Neurol. 2007; 45(4):254. Spanish.
64. Pathai S, Martin KR, Fernandes H. Blurred vision and headaches in a patient with hydrocephalus is not always due to shunt malfunction. Br J Neurosurg. 2007;21(6):633.
65. Singh SK, Thapa SS, Badhu BP. Topiramate induced bilateral angleclosure glaucoma. Kathmandu Univ Med J (KUMJ). 2007;5(2): 234-236.
66. Stangler F, Prietsch RF, Fortes Filho JB. Bilateral acute angle closure glaucoma in a young patient receiving oral topiramate: case report. Arq Bras Oftalmol. 2007;70(1):133-136. Portugese.
67. Aminlari A, East M, Wei W, Quillen D. Topiramate induced acute angle closure glaucoma. Open Ophthalmol J. 2008;2:46-47.
68. Boonyaleephan S. Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: a case report. J Med Assoc Thai. 2008; 91(12):1904-1907.
69. Chalam KV, Tillis T, Syed F, Agarwal S, Brar VS. Acute bilateral simultaneous angle closure glaucoma after topiramate administration: a case report. J Med Case Reports. 2008;2:1.
70. Giuliari GP, Banda RM, Vann VR, Gonzalez VH, McMillin RB. Closedangle glaucoma after topiramate therapy for migraine in a patient with undiagnosed pseudotumor cerebri. Can J Ophthalmol. 2008;43(3):371.
71. Mandal A, Chatterjee S, Bose S, Ganguly G. Ocular adverse effects of topiramate: two case reports. Indian J Pharmacol. 2008;40(6): 278-280.
72. Tsui I, Casper D, Chou CL, Tsang SH. Electronegative electroretinogram associated with topiramate toxicity and vitelliform maculopathy. Doc Ophthalmol. 2008; 116(1):57-60.
73. Fontenelle LF. Topiramate-induced palinopsia. J Neuropsychiatry Clin Neurosci. 2008;20(2):249-250.
74. Zalta AH, Smith RT. Peripheral iridoplasty efficacy in refractory topiramate-associated bilateral acute angle-closure glaucoma. Arch Ophthalmol. 2008;126(11):1603-1605.
75. Dey KK, Das S, Mishra A, Guha G. Retinal detachment presumably associated with topiramate. Neurol India. 2008;56(2):204-205.
76. Brandao MN, Fernandes IC, Barradas FF, Machado JF, Oliveira MT. Acute myopia and angle closure glaucoma associated with topiramate use in a young patient: case report. Arq Bras Oftalmol. 2009; 72(1): 103-105. Portuguese.
77. Cole KL, Wang EE, Aronwald RM. Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report. J Emerg Med. 2009. [Epub ahead of print.]
78. Vilar Ventura RM, Vilar Fabra C, Ramos Marti F. Acute myopia secondary to treatment with topiramate. Neurologia. 2009;24(5):350. Spanish.
79. Gawley SD. Topiramate induced acute transient myopia: a case report. Cases J. 2009;2:7430.
80. Beyenburg S, Weyland C, Reuber M. Presumed topiramate-induced maculopathy. Epilepsy Behav. 2009;14(3):556-559.
81. Sbeity Z, Gvozdyuk N, Amde W, Liebmann JM, Ritch R. Argon laser peripheral iridoplasty for topiramate-induced bilateral acute angle closure. J Glaucoma. 2009;18(4):269-271.
82. Spaccapelo L, Leschiutta S, Aurea C, Ferrari A. Topiramate-associated acute glaucoma in a migraine patient receiving concomitant citalopram therapy: a case-report. Cases J. 2009;2(1):87.
83. Kerimoglu H, Tokgoz M, Ozturk B, Gonul S, Pekel H. Topiramateinduced acute-onset myopia and central corneal thickening: Pentacam Scheimpflug imaging findings. Can J Ophthalmol. 2009; 44(2): 222-223.
84. Acharya N, Nithyanandam S, Kamat S. Topiramate-associated bilateral anterior uveitis and angle closure glaucoma. Indian J Ophthalmol. 2010; 58(6):557-559.
85. Natesh S, Rajashekhara SK, Rao AS, Shetty B. Topiramate-induced angle closure with acute myopia, macular striae. Oman J Ophthalmol. 2010;3(1):26-28.
86. Tahiri Joutei Hassani R, Dupont Monod S, Oukacha G, et al. Acute bilateral angle-closure glaucoma induced by topiramate: contribution of Visante OCT. J Fr Ophtalmol. 2010; 33(5):307-311. French.
87. Senthil S, Garudadri C, Rao HB, Maheshwari R. Bilateral simultaneous acute angle closure caused by sulphonamide derivatives: a case series. Indian J Ophthalmol. 2010;58(3):248-252.
88. Van Issum C, Mavrakanas N, Schutz JS, Shaarawy T. Topiramate-induced acute bilateral angle closure and myopia: pathophysiology and treatment controversies. Eur J Ophthalmol. 2011;21(4):404-409.
89. Jabbarpoor Bonyadi MH, Soheilian R, Soheilian M. Topiramateinduced bilateral anterior uveitis associated with hypopyon formation. Ocul Immunol Inflamm. 2011;19(1):86-88.
90. Pai K, Rajashekaran P. Glaucoma: adverse event on use of topiramate in alcohol de-addiction. Indian J Psychiatry. 2011;53(2):163-165.
91. Tanaka S, Chuman Y, Akaike K, Doi W. A case of topiramate-induced angle closure glaucoma. Nihon Shinkei Seishin Yakurigaku Zasshi. 2011;31(3):131-133. Japanese.
92. Willett MC, Edward DP. Refractory topiramate-induced angleclosure glaucoma in a man: a case report. J Med Case Reports. 2011; 5(1):33.
93. Muether PS, Welsandt G, Dietlein TS. Panic after LASIK: acute medication-induced myopic recurrence after refractive surgery. Ophthalmologe. 2011;108(2):164-166. German.
94. Dorronzoro E, Santos-Bueso E, Vico-Ruiz E, Saenz-Frances F, Argaya J, Gegundez-Fernandez JA. Myopia and retinal striae induced by topiramate. Arch Soc Esp Oftalmol. 2011;86(1): 24-26. Spanish.
95. Jurgens TP, Ihle K, Stork JH, May A. Alice in Wonderland syndrome associated with topiramate for migraine prevention. J Neurol Neurosurg Psychiatry. 2011;82(2):228-229.
96. Dehghani A, Abtahi MA, Abtahi SH, et al. Massive bilateral choroidal detachment induced by administration of topiramate. Case Report Ophthalmol. 2011;2(2):251-255.
97. Ikeda N, Ikeda T, Nagata M, Mimura O. Ciliochoroidal effusion syndrome induced by sulfa derivatives. Arch Ophthalmol. 2002; 120(12):1775.
98. Doherty MD, Wride NK, Birch MK, Figueiredo FC. Choroidal detachment in association with topical dorzolamide: is hypotony always the cause? Clin Experiment Ophthalmol. 2009;37(7):750-752.
99. Natesh S. Topiramate and rhegmatogenous retinal detachment. Neurol India. 2009;57(2):224-225.
100. Di Legge S, Bruti G, Di Piero V, Lenzi G. Topiramate versus migraine: which is the cause of glaucomatous visual field defects? Headache. 2002;42(8):837-838.