Tensile Stress Regulation of NGF and NT3 in Human Dermal Fibroblast

IFMBE Proceedings

Volumn 23, Issue , 2009, Pages 1935-1937

  Kim, Mina ^a   Hong, J W ^a   Nho, Minsoo ^b   Na, Yong Joo ^b   Shin, Jennifer Hyunjong ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Amore pacific Corporation R and D Center   (South Korea)

Author keywords

Fibroblast; NGF; NT3; Tensile stress

Indexed keywords

BIOMECHANICAL PROPERTIES; FIBROBLAST MIGRATION; HUMAN DERMAL FIBROBLASTS; NGF; NT3; POLYDIMETHYLSILOXANE (PDMS) SUBSTRATES; SKIN FIBROBLAST CELLS; STRAIN AND FREQUENCY;

BIOMEDICAL ENGINEERING; CELL CULTURE; COLLAGEN; ENZYME INHIBITION; MUSCULOSKELETAL SYSTEM; SILICONES; TENSILE STRESS; TRANSCRIPTION;

FIBROBLASTS;

EID: 84856968734     PISSN: 16800737     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1007/978-3-540-92841-6_481     Document Type: Conference Paper

References (9)

1. Riley GP (2005) Gene expression and matrix turnover in overused and damaged tendons. Scand J Med Sci Sport 15: 241-251
2. MacKenna D, Summerour SR and Villarreal FJ (2000) Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. Cardiovasc Res 46:257-263
3. Wang JH, Thampatty BP, Lin JS et al (2007) Mechanoregulation of gene expression in fibroblasts. Gene 391:1-15
4. Silver FH, Siperko LM, Seehra GP. (2003) Mechanobiology of force transduction in dermal tissue. Skin Res Technol 9: 3-23
5. Yang G, Crawford RC, Wang JH (2004) Proliferation and collagene production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech 37:1543-1550
6. Tsuzaki M, Bynum D, Almekinders L et al (2003) ATP modulates load-inducible IL-1beta, COX 2, and MMP-3 gene expression in human tendon cells. J Cell Biochem 89:556-562
7. Tsuzaki M, Guyton G, Garrett W et al (2003) IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells. J Orthop Res 21:256-264
8. Yaar M (1999) Neurotrophins in skin. In: Neurotrophins and the neural crest. CRC Press, London.
9. Bonte F, Viennet C, Dumas M et al (2006) NGF presents tensile properties in human skin dermis. Cell Research 16: S1-S9