Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis

Human Molecular Genetics

Volumn 21, Issue 5, 2012, Pages 1025-1036

  Gr̈ger, Nicole ^a   Vitzthum, Helga ^b   Fr̈hlich, Henning ^a,c   Kr̈ger, Marcus ^a   Ehmke, Heimo ^b   Braun, Thomas ^a   Boettger, Thomas ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; PENDRIN; PROTEIN; SLC4A5 PROTEIN; SODIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SIZE; CHOROID PLEXUS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOWN REGULATION; EXON; FLUID INTAKE; GENE FUNCTION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GLOMERULUS FILTRATION RATE; HYPERTENSION; HYPOALDOSTERONISM; IN SITU HYBRIDIZATION; KIDNEY CORTEX; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; MALE; METABOLIC ACIDOSIS; MOUSE; NONHUMAN; OPEN READING FRAME; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SODIUM ABSORPTION; SODIUM TRANSPORT; SYSTOLIC BLOOD PRESSURE; UPREGULATION; URINARY EXCRETION;

ACID-BASE EQUILIBRIUM; ACIDOSIS, RENAL TUBULAR; ALDOSTERONE; ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD; BLOOD CHEMICAL ANALYSIS; BLOOD PRESSURE; GENE EXPRESSION REGULATION; GLOMERULAR FILTRATION RATE; HYDROGEN-ION CONCENTRATION; HYPERTENSION; IN SITU HYBRIDIZATION; KIDNEY; KIDNEY TUBULES; MALE; MICE; MUTATION; SEQUENCE DELETION; SODIUM; SODIUM BICARBONATE; SODIUM-BICARBONATE SYMPORTERS; URINATION; URINE;

EID: 84856951870     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr533     Document Type: Article

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