3-(2,6-Dimethylphenyl)-2-selenoxo-1,3-thiazolidin-4-one suppresses hydrogen peroxide-induced cytotoxicity on PC12 cells via activation of MAPK

International Journal of Toxicology

Volumn 30, Issue 6, 2011, Pages 690-699

  Nishina, Atsuyoshi ^a   Kimura, Hirokazu ^b   Kozawa, Kunihisa ^b   Sommen, Geoffroy ^c   Favero, Francesco ^d   Heimgartner, Heinz ^e   Koketsu, Mamoru ^f   Furukawa, Shoei ^g  

^a Yonezawa Women's Junior College   (Japan)

^b GUNMA PREFECTURAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENTAL SCIENCES   (Japan)

^c Lonza Braine SA   (Belgium)

^d Edo Tempia Foundation   (Italy)

^e UNIVERSITY OF ZURICH   (Switzerland)

^f GIFU UNIVERSITY   (Japan)

^g GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

3 (2; 3 thiazolidin 4 one; 6 dimethylphenyl) 2 selenoxo 1; MAPK; PC12 cells; Phosphorylation; Superoxide anion scavenging activities

Indexed keywords

3 (2,6 DIMETHYLPHENYL) 2 SELENOXO 1,3 THIAZOLIDIN 4 ONE; 3 (4 BROMOPHENYL) 2 SELENOXO 1,3 THIAZOLIDIN 4 ONE; 3 (4 METHOXYLPHENYL) 2 SELENOXO 1,3 THIAZOLIDIN 4 ONE; 3 (4 METHYLPHENYL) 2 SELENOXO 1,3 THIAZOLIDIN 4 ONE; CARBOXYLIC ACID DERIVATIVE; EBSELEN; ETHYL 3 ETHOXY 4 (4 FLUOROPHENYL) 4,5 DIHYDRO 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; ETHYL 3 ETHOXY 4,5 DIHYDRO 4 (4 METHYLPHENYL) 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; ETHYL 3 ETHOXY 4,5 DIHYDRO 4 PHENYL 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; ETHYL 4 (4 BROMOPHENYL) 3 ETHOXY 4,5 DIHYDRO 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; ETHYL 4 (4 CHLOROPHENYL) 3 ETHOXY 4,5 DIHYDRO 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SCAVENGER; TERT BUTYL 3 (TERT BUTOXY) 4 (4 BROMOPHENYL) 3 ETHOXY 4,5 DIHYDRO 5 SELENOXO 1H 1,2,4 TRIAZOLE 1 CARBOXYLATE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN; CELL SURVIVAL; CELL VIABILITY; CHEMOLUMINESCENCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; IC 50; NONHUMAN; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; RAT; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; CELL PROLIFERATION; CELL SURVIVAL; HYDROGEN PEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASES; ORGANOSELENIUM COMPOUNDS; PC12 CELLS; RATS; SUPEROXIDES;

RATTUS;

EID: 84856946950     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581811419267     Document Type: Article

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