Insulin pumps in pregnancy: Using technology to achieve normoglycemia in women with diabetes

Current Diabetes Reports

Volumn 12, Issue 1, 2012, Pages 53-59

  Castorino, Kristin ^a   Paband, Rashid ^b   Zisser, Howard ^a   Jovanovič, Lois ^a  

^a SANSUM DIABETES RESEARCH INSTITUTE   (United States)

^b SANTA BARBARA COTTAGE HOSPITAL   (United States)

Author keywords

Artificial Pancreas System; Continuous Subcutaneous Insulin Infusion; Diabetes; Gestational Pre existing Diabetes; Insulin Delivery System; Insulin Management System; Insulin Pump Technology; Multiple Daily Injections; Normoglycemia; Postprandial Hyperglycemia; Pregnancy; T1DM, T2DM

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN ASPART; INSULIN GLARGINE; INSULIN LISPRO; ISOPHANE INSULIN;

ARTICLE; BEDTIME DOSAGE; BREAST FEEDING; COMPUTER INTERFACE; COMPUTER PROGRAM; CONTINUOUS INFUSION; DELIVERY; DISEASE ASSOCIATION; DRUG ADMINISTRATION ROUTE; DRUG EFFICACY; DRUG INDICATION; DRUG SAFETY; FETUS OUTCOME; FIRST TRIMESTER PREGNANCY; FOOD AND DRUG ADMINISTRATION; GESTATIONAL AGE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEMOGLOBIN BLOOD LEVEL; HIGH RISK PREGNANCY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INSULIN PUMP; LABOR; LACTATION; MATERNAL DIABETES MELLITUS; MEDICAL TECHNOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT PREFERENCE; PLACENTAL TRANSFER; PRACTICE GUIDELINE; PREGNANCY DIABETES MELLITUS; PREGNANCY OUTCOME; PREGNANT WOMAN; RECOMMENDED DRUG DOSE; RISK REDUCTION;

BLOOD GLUCOSE; CONGENITAL ABNORMALITIES; COUNSELING; DIABETES MELLITUS, TYPE 2; FEMALE; GUIDELINES AS TOPIC; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN INFUSION SYSTEMS; LACTATION; OBESITY; PREGNANCY; PREGNANCY IN DIABETICS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84856906010     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-011-0242-7     Document Type: Article

References (38)

1. L Jovanovič DJ Pettitt 2007 Treatment with insulin and its analogs in pregnancy complicated by diabetes Diabetes Care 30 S220 S224 17596476 10.2337/dc07-s220 (Pubitemid 47036429)
2. L Jovanovič CM Peterson GF Reed, et al. 1991 Maternal postprandial blood glucose levels and infant birth weight: the diabetes in early pregnancy study. The national institute of child health and humand development-diabetes in early pregnancy study Am J Obstet Gynecol 164 103 111
3. B Kinsley 2007 Achieving better outcomes in pregnancies complicated by type 1 and type 2 diabetes mellitus Clin Ther 29 Suppl D S153 S160 18191067 10.1016/j.clinthera.2007.12.015 1:CAS:528:DC%2BD1cXitVKgu74%3D
4. JL Kitzmiller JP Cloherty MD Younger, et al. 1978 Diabetic pregnancy and perinatal outcome Am J Obstet Gynecol 131 560 580 354386 1:STN:280: DyaE1c3jt1Oksw%3D%3D
5. EA Reece S Gabriella M Abdalla 1988 The prevention of diabetes associated birth defects Semin Perinatol 12 292 302 3065942 1:STN:280:DyaL1M7jtVajtQ%3D%3D
6. M Miodovnik JP Lavin HC Knowles, et al. 1984 Spontaneous abortion among insulin-dependent diabetic women Am J Obstet Gynecol 150 372 375 6207729 1:STN:280:DyaL2M%2FitValtA%3D%3D
7. Jovanovič L. Prepregnancy counseling and management of women with preexisting diabetes or previous gestational diabetes. In: Jovanovič L, editor. Medical management of pregnancy complicated by diabetes. 4th ed. Virginia: American Diabetes Association Press; 2009.
8. AD Wollitzer H Zisser L Jovanovič 2010 Insulin pumps and their use in pregnancy Diabetes Technol Ther 12 Suppl1 33 36
9. D Dabelea EJ Mayer-Davis AP Lamichhane, et al. 2008 Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth the SEARCH case-control study Diabetes Care 31 7 1422 1426 18375420 10.2337/dc07-2417
10. LL Liu JM Lawrence C Davis, et al. 2010 Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for diabetes in youth study Pediatr Diabetes 11 4 4 11 19473302 10.1111/j.1399-5448.2009.00519.x
11. Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2011.
12. K Castorino L Jovanovič 2011 Pregnancy and diabetes management: advances and controversies Clin Chem 57 221 230 21148303 10.1373/clinchem.2010. 155382 1:CAS:528:DC%2BC3MXislaju7s%3D This is a review article on the diagnosis and management of diabetes in pregnancy, which provides background information and complements this article
13. ML Misso KJ Egberts M Page, et al. 2010 Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus Cochrane Database Syst Rev 1 CD005103 20091571
14. Petrovski G, Dimitrovski C, Bogoev M, et al.: Is there a difference in pregnancy and glycemic outcome in patients with type 1 diabetes on insulin pump with constant or intermittent glucose monitoring? A pilot study. Diabetes Technol Ther 2011 (Epublish ahead of print).
15. A Chico I Saigi A Garcia-Patterson, et al. 2010 Glycemic control and perinatal outcomes of pregnancies complicated by type 1 diabetes: influence of continuous subcutaneous insulin infusion and lispro insulin Diabetes Technol Ther 12 937 945 21128840 10.1089/dia.2010.0111 1:CAS:528:DC%2BC3cXhsFaqsLbO This is one of the few recent clinical trials evaluating insulin pumps in pregnancy, which had mixed results for CSII compared with MDI
16. 1cs were above 6.0% for both groups at delivery.
17. J Hone L Jovanovič 2010 Approach to the patient with diabetes during pregnancy J Clin Endocrinol Metab 95 3578 3585 20685884 10.1210/jc.2010-0383 1:CAS:528:DC%2BC3cXhtVGktrrL
18. IW Gallen A Jaap JM Roland HH Chirayath 2008 Survey of glargine use in 115 pregnant women with Type 1 diabetes Diabet Med 25 165 169 18215174 10.1111/j.1464-5491.2007.02339.x 1:CAS:528:DC%2BD1cXktVajs7o%3D (Pubitemid 351293402)
19. MP Imbergamo MC Amato G Sciortino, et al. 2008 Use of glargine in pregnant women with type 1 diabetes mellitus: a case-control study Clin Ther 30 1476 1484 18803989 10.1016/j.clinthera.2008.08.013 1:CAS:528:DC%2BD1cXhtF2rtb7M
20. Castorino K, Wollitzer AO, Pettitt DJ, Zisser H, Jovanovič L.: 50/50 insulin mix 3x per day simplifies insulin regimen in GDM [abstract DIAEAZ 60]. Presented at the 71st Scientific Sessions of the American Diabetes Association. San Diego, California; June 24-28, 2011.
21. SG Gabbe E Holing P Temple, et al. 2000 Benefits, risks, costs and patient satisfaction associated with insulin pump therapy for the pregnancy complicated by type 1 diabetes mellitus Am J Obstet Gynecol 182 1283 1291 10871440 10.1067/mob.2000.106182 1:STN:280:DC%2BD3czivFGnsQ%3D%3D (Pubitemid 30437391)
22. L Volpe F Pancani M Aragona, et al. 2009 Continuous subcutaneous insulin infusion and multiple dose injections in type 1 diabetic pregnanct women: a case-control study Gynecol Endocrinol 31 1 4 10.1080/09513590903215540
23. Farrar D, Tuffnell DJ, West J,: Continuous subcutaneous insulin infusion versus multipe daily injections of insulin for pregnant women with diabetes. Cochrane Database Syst Rev 2007; (3):CD005542.
24. SF Gabbe LB Carpenter EA Garrison 2007 New strategies for glucose control in patients with type 1 and type 2 diabetes mellitus in pregnancy Clin Obstet Gynecol 50 1014 1024 17982345 10.1097/GRF.0b013e31815a6435 (Pubitemid 350059299)
25. H Hanaire V Lassmann-Vague N Jeandidier, et al. 2008 Treatment of diabetes mellitus using an external insulin pump: the state of the art Diabetes Metab 34 401 423 18951116 10.1016/S1262-3636(08)73972-7 1:CAS:528: DC%2BD1cXhtlGgtbnN
26. Jovanovič L. Use of insulin during pregnancy in preexisting diabetes. In: Jovanovič L, editor. Medical management of pregnancy complicated by diabetes. 4th ed. Virginia: American Diabetes Association Press; 2009.
27. Mathiesen ER, Damm P, Jovanovič L, et al.: Clinical experience with basal insulin analogs in diabetic pregnancy: details of a randomized controlled trial in type 1 diabetese and a review of the literature. Diabetes Metab Res Rev 2011. [Epub ahead of print].
28. K Cypryk M Sobczak M Pertynska-Marczewska, et al. 2004 Pregnancy complications and perinatal outcome in diabetic women treated with humalog (insulin lispro) or regular human insulin during pregnancy Med Sci Monit 10 I29 I132
29. A Lapolla MG Dalfra R Spezia, et al. 2008 Outcome of pregnancy in type 1 diabetic patients treated with insulin lispro or regular insulin: an Italian experience Acta Diabetol 45 61 66 18227964 10.1007/s00592-008-0024-0 1:CAS:528:DC%2BD1cXhs1yltbc%3D
30. EA Masson JE Patmore PD Brash, et al. 2003 Pregnancy outcome in type 1 diabetes mellitus treated with insulin lispro (Humalog) Diabet Med 20 46 50 12519319 10.1046/j.1464-5491.2003.00840.x 1:CAS:528:DC%2BD3sXht1Sks7c%3D (Pubitemid 36104202)
31. ER Mathiesen B Kinsley SA Amiel, et al. 2007 Maternal glycemic control and hypoglycemia in type 1 diabetic pregnancy: a randomized trial of insulin aspart versus human insulin in 322 pregnant women Diabetes Care 30 771 776 17392539 10.2337/dc06-1887 1:CAS:528:DC%2BD2sXkvVOgtb8%3D (Pubitemid 46556565)
32. Handelsman Y, Blonde L, Bloomgarden Z, et al.: American Academy of Clinical Endocrinologists medical guidelines for clinical practice for developing a diabetes mellitus comprehensive care plan. Endocrine Practice 2011,17(Suppl 2). https://www.aace.com/sites/default/files/DMGuidelinesCCP.pdf.
33. DR McCance P Damm ER Mathiesen, et al. 2008 Evaluation of insulin antibodies and placental transfer of insulin aspart in pregnant women with type 1 diabetes mellitus Diabetologia 51 2141 2143 18726086 10.1007/s00125-008-1120-y 1:STN:280:DC%2BD1cnksVymsg%3D%3D
34. L Jovanovič M Druzin CM Peterson 1981 Effect of Euglycemia on outcome of pregnancy in insulin-dependent diabetic women as compared to normal control subjects Am J Med 71 921 927 7032287 10.1016/0002-9343(81)90301-6 (Pubitemid 12191971)
35. Jovanovič, Lois: Glucose and Insulin Requirements During Labor and Delivery; The Care for Normoglycemia in Pregnancy Complicated by Diabetes. Endocrine Practice 2004, Supplement 2.
36. H de Valk GH Visser 2011 Insulin during pregnancy, Labour and delivery Best Pract Res Clin Obstet Gynaecol 17 65 76 10.1016/j.bpobgyn.2010.10.002
37. C Riviello G Mello L Jovanovič 2009 Breastfeeding and the basal insulin requirement in type 1 diabetic women Endocr Pract 15 187 193 19364685
38. HR Murphy D Elleri JM Allen, et al. 2011 Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes Diabetes Care 34 406 411 21216859 10.2337/dc10-1796 1:CAS:528:DC%2BC3MXis1Crtbo%3D This exciting clinical trial evaluated CSII in conjunction with continuous glucose sensor to form an artificial pancreas system. Although the system did not appropriately treat postprandial hyperglycemia, it offers an attractive solution for the management of insulin-requiring diabetes