-
1
-
-
66149139289
-
Efficacy and safety of casopitant mesylate, a neurokinin 1 (NK1)-receptor antagonist, in prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy: A randomised, double-blind, placebo-controlled trial
-
Grunberg SM, Rolski J, Strausz J et al. Efficacy and safety of casopitant mesylate, a neurokinin 1 (NK1)-receptor antagonist, in prevention of chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based highly emetogenic chemotherapy: A randomised, double-blind, placebo-controlled trial. Lancet Oncol. 10, 549-558 (2009).
-
(2009)
Lancet Oncol
, vol.10
, pp. 549-558
-
-
Grunberg, S.M.1
Rolski, J.2
Strausz, J.3
-
2
-
-
73949158930
-
Phase III trial of casopitant, a novel neurokinin-1 receptor antagonist, for the prevention of nausea and vomiting in patients receiving moderately emetogenic chemotherapy
-
Herrstedt J, Apornwirat W, Shaharyar A et al. Phase III trial of casopitant, a novel neurokinin-1 receptor antagonist, for the prevention of nausea and vomiting in patients receiving moderately emetogenic chemotherapy. J. Clin. Oncol. 27, 5363-5369 (2009).
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 5363-5369
-
-
Herrstedt, J.1
Apornwirat, W.2
Shaharyar, A.3
-
3
-
-
0347816226
-
The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: A multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin - The Aprepitant Protocol 052 Study Group
-
DOI 10.1200/JCO.2003.01.095
-
Hesketh PJ, Grunberg SM, Gralla RJ et al. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: A multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin - the Aprepitant Protocol 052 Study Group. J. Clin. Oncol. 21, 4112-4119 (2003). .. One of the two pivotal Phase III aprepitant trials in patients receiving highly emetogenic chemotherapy. (Pubitemid 46606178)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.22
, pp. 4112-4119
-
-
Hesketh, P.J.1
Grunberg, S.M.2
Gralla, R.J.3
Warr, D.G.4
Roila, F.5
De Wit, R.6
Chawla, S.P.7
Carides, A.D.8
Ianus, J.9
Elmer, M.E.10
Evans, J.K.11
Beck, K.12
Reines, S.13
Horgan, K.J.14
-
4
-
-
0038728753
-
Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting: Results from a randomized, double-blind, placebo-controlled trial in Latin America
-
DOI 10.1002/cncr.11433
-
Poli-Bigelli S, Rodrigues-Pereira J, Carides AD et al. Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin America. Cancer 97, 3090-3098 (2003). .. One of two pivotal Phase III aprepitant trials in patients receiving highly emetogenic chemotherapy. (Pubitemid 36676265)
-
(2003)
Cancer
, vol.97
, Issue.12
, pp. 3090-3098
-
-
Poli-Bigelli, S.1
Rodrigues-Pereira, J.2
Carides, A.D.3
Ma, G.J.4
Eldridge, K.5
Hipple, A.6
Evans, J.K.7
Horgan, K.J.8
Lawson, F.9
-
5
-
-
21044434743
-
Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy
-
DOI 10.1200/JCO.2005.09.050
-
Warr DG, Hesketh PJ, Gralla RJ et al. Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy. J. Clin. Oncol. 23, 2822-2830 (2005). .. Pivotal Phase III aprepitant trial in patients receiving moderately emetogenic chemotherapy. (Pubitemid 46179473)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.12
, pp. 2822-2830
-
-
Warr, D.G.1
Hesketh, P.J.2
Gralla, R.J.3
Muss, H.B.4
Herrstedt, J.5
Eisenberg, P.D.6
Raftopoulos, H.7
Grunberg, S.M.8
Gabriel, M.9
Rodgers, A.10
Bohidar, N.11
Klinger, G.12
Hustad, C.M.13
Horgan, K.J.14
Skobieranda, F.15
-
6
-
-
0020699588
-
On the receiving end - patient perception of the side-effects of cancer chemotherapy
-
DOI 10.1016/0277-5379(83)90418-2
-
Coates A, Abraham S, Kaye SB et al. On the receiving end - patient perception of the side-effects of cancer chemotherapy. Eur. J. Cancer Clin. Oncol. 19, 203-208 (1983). (Pubitemid 13155858)
-
(1983)
European Journal of Cancer and Clinical Oncology
, vol.19
, Issue.2
, pp. 203-208
-
-
Coates, A.1
Abraham, S.2
Kaye, S.B.3
-
7
-
-
0030845779
-
Patient perceptions of the side-effects of chemotherapy: The influence of 5HT3 antagonists
-
de Boer-Dennert M, de Wit R, Schmitz PI et al. Patient perceptions of the side-effects of chemotherapy: The influence of 5HT3 antagonists. Br. J. Cancer 76, 1055-1061 (1997). (Pubitemid 27434663)
-
(1997)
British Journal of Cancer
, vol.76
, Issue.8
, pp. 1055-1061
-
-
De Boer-Dennert, M.1
De Wit, R.2
Schmitz, P.I.M.3
Djontono, J.4
Beurden, V.V.5
Stoter, G.6
Verweij, J.7
-
8
-
-
0029866092
-
On the receiving end V: Patient perceptions of the side effects of cancer chemotherapy in 1993
-
Griffin AM, Butow PN, Coates AS et al. On the receiving end. V: Patient perceptions of the side effects of cancer chemotherapy in 1993. Ann. Oncol. 7, 189-195 (1996). (Pubitemid 26094884)
-
(1996)
Annals of Oncology
, vol.7
, Issue.2
, pp. 189-195
-
-
Griffin, A.M.1
Butow, P.N.2
Coates, A.S.3
Childs, A.M.4
Ellis, P.M.5
Dunn, S.M.6
Tattersall, M.H.N.7
-
9
-
-
84856850633
-
Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: Results of the Perugia consensus conference. Ann. Oncol. 21(Suppl. 5), v232-v243 (2010). . Most recently updated and clinically applicable antiemetic guidelines. 10 Maggi CA. The mammalian tachykinin receptors
-
Roila F, Herrstedt J, Aapro M et al. Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: Results of the Perugia consensus conference. Ann. Oncol. 21(Suppl. 5), v232-v243 (2010). . Most recently updated and clinically applicable antiemetic guidelines. 10 Maggi CA. The mammalian tachykinin receptors. Gen. Pharmacol. 26, 911-944 (1995).
-
(1995)
Gen. Pharmacol
, vol.26
, pp. 911-944
-
-
Roila, F.1
Herrstedt, J.2
Aapro, M.3
-
10
-
-
0027165533
-
Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret
-
DOI 10.1016/0028-3908(93)90189-A
-
Andrews PL, Bhandari P. Resinferatoxin, an ultrapotent capsaicin analogue, has anti-emetic properties in the ferret. Neuropharmacology 32, 799-806 (1993). (Pubitemid 23227666)
-
(1993)
Neuropharmacology
, vol.32
, Issue.8
, pp. 799-806
-
-
Andrews, P.L.R.1
Bhandari, P.2
-
12
-
-
0026099914
-
1) receptor
-
Snider RM, Constantine JW, Lowe JA III et al. A potent nonpeptide antagonist of the substance P (NK1) receptor. Science 251, 435-437 (1991). (Pubitemid 21916907)
-
(1991)
Science
, vol.251
, Issue.4992
, pp. 435-437
-
-
Snider, R.M.1
Constantine, J.W.2
Lowe III, J.A.3
Longo, K.P.4
Lebel, W.S.5
Woody, H.A.6
Drozda, S.E.7
Desai, M.C.8
Vinick, F.J.9
Spencer, R.W.10
Hess, H.-J.11
-
13
-
-
0034704822
-
Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs
-
DOI 10.1021/jm990617v
-
Hale JJ, Mills SG, MacCoss M et al. Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs. J. Med. Chem. 43, 1234-1241 (2000). (Pubitemid 30173749)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.6
, pp. 1234-1241
-
-
Hale, J.J.1
Mills, S.G.2
MacCoss, M.3
Dorn, C.P.4
Finke, P.E.5
Budhu, R.J.6
Reamer, R.A.7
Huskey, S.-E.W.8
Luffer-Atlas, D.9
Dean, B.J.10
McGowan, E.M.11
Feeney, W.P.12
Chiu, S.-H.L.13
Cascieri, M.A.14
Chicchi, G.G.15
Kurtz, M.M.16
Sadowski, S.17
Ber, E.18
Tattersall, F.D.19
Rupniak, N.M.J.20
Williams, A.R.21
Rycroft, W.22
Hargreaves, R.23
Metzger, J.M.24
MacIntyre, D.E.25
more..
-
14
-
-
10744224396
-
The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs
-
DOI 10.1124/dmd.32.2.246
-
Huskey SE, Dean BJ, Doss GA et al. The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs. Drug Metab. Dispos. 32, 246-258 (2004). (Pubitemid 38176943)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.2
, pp. 246-258
-
-
Huskey, S.-E.W.1
Dean, B.J.2
Doss, G.A.3
Wang, Z.4
Hop, C.E.C.A.5
Anari, R.6
Finke, P.E.7
Robichaud, A.J.8
Zhang, M.9
Wang, B.10
Strauss, J.R.11
Cunningham, P.K.12
Feeney, W.P.13
Franklin, R.B.14
Baillie, T.A.15
Chiu, S.-H.L.16
-
15
-
-
0037855786
-
Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets
-
Huskey SE, Dean BJ, Bakhtiar R et al. Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets. Drug Metab. Dispos. 31, 785-791 (2003). (Pubitemid 36617669)
-
(2003)
Drug Metabolism and Disposition
, vol.31
, Issue.6
, pp. 785-791
-
-
Huskey, S.-E.W.1
Dean, B.J.2
Bakhtiar, R.3
Sanchez, R.I.4
Tattersall, F.D.5
Rycroft, W.6
Hargreaves, R.7
Watt, A.P.8
Chicchi, G.G.9
Keohane, C.10
Hora, D.F.11
Chiu, S.-H.L.12
-
16
-
-
2342483811
-
Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant
-
DOI 10.1016/j.biopsych.2004.02.007, PII S0006322304001854
-
Bergstrom M, Hargreaves RJ, Burns HD et al. Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant. Biol. Psychiatry 55, 1007-1012 (2004). (Pubitemid 38581916)
-
(2004)
Biological Psychiatry
, vol.55
, Issue.10
, pp. 1007-1012
-
-
Bergstrom, M.1
Hargreaves, R.J.2
Burns, H.D.3
Goldberg, M.R.4
Sciberras, D.5
Reines, S.A.6
Petty, K.J.7
Ogren, M.8
Antoni, G.9
Langstrom, B.10
Eskola, O.11
Scheinin, M.12
Solin, O.13
Majumdar, A.K.14
Constanzer, M.L.15
Battisti, W.P.16
Bradstreet, T.E.17
Gargano, C.18
Hietala, J.19
-
17
-
-
0032755004
-
Substance P receptor antagonist I: Conversion of phosphoramidate prodrug after i.v. administration to rats and dogs
-
Huskey SE, Luffer-Atlas D, Dean BJ et al. Substance P receptor antagonist I: Conversion of phosphoramidate prodrug after i.v. administration to rats and dogs. Drug Metab. Dispos. 27, 1367-1373 (1999).
-
(1999)
Drug Metab. Dispos
, vol.27
, pp. 1367-1373
-
-
Huskey, S.E.1
Luffer-Atlas, D.2
Dean, B.J.3
-
18
-
-
34548008132
-
Tolerability of fosaprepitant and bioequivalency to aprepitant in healthy subjects
-
Lasseter KC, Gambale J, Jin B et al. Tolerability of fosaprepitant and bioequivalency to aprepitant in healthy subjects. J. Clin. Pharmacol. 47, 834-840 (2007).
-
(2007)
J. Clin. Pharmacol
, vol.47
, pp. 834-840
-
-
Lasseter, K.C.1
Gambale, J.2
Jin, B.3
-
19
-
-
6944235904
-
Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant
-
DOI 10.1124/dmd.104.000216
-
Sanchez RI, Wang RW, Newton DJ et al. Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant. Drug Metab. Dispos. 32, 1287-1292 (2004). (Pubitemid 39410914)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.11
, pp. 1287-1292
-
-
Sanchez, R.I.1
Wang, R.W.2
Newton, D.J.3
Bakhtiar, R.4
Lu, P.5
Chiu, S.-H.L.6
Evans, D.C.7
Huskey, S.-E.W.8
-
20
-
-
32944458444
-
Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers
-
DOI 10.1177/0091270005283467
-
Majumdar AK, Howard L, Goldberg MR et al. Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers. J. Clin. Pharmacol. 46, 291-300 (2006). (Pubitemid 43260316)
-
(2006)
Journal of Clinical Pharmacology
, vol.46
, Issue.3
, pp. 291-300
-
-
Majumdar, A.K.1
Howard, L.2
Goldberg, M.R.3
Hickey, L.4
Constanzer, M.5
Rothenberg, P.L.6
Crumley, T.M.7
Panebianco, D.8
Bradstreet, T.E.9
Bergman, A.J.10
Waldman, S.A.11
Greenberg, H.E.12
Butler, K.13
Knops, A.14
De Lepeleire, I.15
Michiels, N.16
Petty, K.J.17
-
21
-
-
0033625089
-
1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L-758,298, inhibit acute and delayed cisplatin- induced emesis in ferrets
-
DOI 10.1016/S0028-3908(99)00172-0, PII S0028390899001720
-
Tattersall FD, Rycroft W, Cumberbatch M et al. The novel NK1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L-758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets. Neuropharmacology 39, 652-663 (2000). (Pubitemid 30089315)
-
(2000)
Neuropharmacology
, vol.39
, Issue.4
, pp. 652-663
-
-
Tattersall, F.D.1
Rycroft, W.2
Cumberbatch, M.3
Mason, G.4
Tye, S.5
Williamson, D.J.6
Hale, J.J.7
Mills, S.G.8
Finke, P.E.9
MacCoss, M.10
Sadowski, S.11
Ber, E.12
Cascieri, M.13
Hill, R.G.14
MacIntyre, D.E.15
Hargreaves, R.J.16
-
22
-
-
0033590464
-
Reduction of cisplatin-induced emesis by a selective neurokinin-1- receptor antagonist
-
DOI 10.1056/NEJM199901213400304
-
Navari RM, Reinhardt RR, Gralla RJ et al. Reduction of cisplatin-induced emesis by a selective neurokinin-1-receptor antagonist. L-754,030 Antiemetic Trials Group. N. Engl. J. Med. 340, 190-195 (1999). (Pubitemid 29063215)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.3
, pp. 190-195
-
-
Navari, R.M.1
Reinhardt, R.R.2
Gralla, R.J.3
Kris, M.G.4
Hesketh, P.J.5
Khojasteh, A.6
Kindler, H.7
Grote, T.H.8
Pendergrass, K.9
Grunberg, S.M.10
Carides, A.D.11
Gertz, B.J.12
-
23
-
-
0035868769
-
Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist, MK-869, in combination with granisetron and dexamethasone or with dexamethasone alone
-
Campos D, Pereira JR, Reinhardt RR et al. Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist, MK-869, in combination with granisetron and dexamethasone or with dexamethasone alone. J. Clin. Oncol. 19, 1759-1767 (2001). (Pubitemid 32230878)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.6
, pp. 1759-1767
-
-
Campos, D.1
Pereira, J.R.2
Reinhardt, R.R.3
Carracedo, C.4
Poli, S.5
Vogel, C.6
Martinez-Cedillo, J.7
Erazo, A.8
Wittreich, J.9
Eriksson, L.-O.10
Carides, A.D.11
Gertz, B.J.12
-
24
-
-
0035053631
-
Comparison of L-758,298, a prodrug for the selective neurokinin-1 antagonist, L-754,030, with ondansetron for the prevention of cisplatin-induced emesis
-
DOI 10.1016/S0959-8049(00)00416-0, PII S0959804900004160
-
Cocquyt V, Van BS, Reinhardt RR et al. Comparison of L-758,298, a prodrug for the selective neurokinin-1 antagonist, L-754,030, with ondansetron for the prevention of cisplatin-induced emesis. Eur. J. Cancer 37, 835-842 (2001). (Pubitemid 32323960)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.7
, pp. 835-842
-
-
Cocquyt, V.1
Van Belle, S.2
Reinhardt, R.R.3
Decramer, M.L.A.4
O'Brien, M.5
Schellens, J.H.M.6
Borms, M.7
Verbeke, L.8
Van Aelst, F.9
De Smet, M.10
Carides, A.D.11
Eldridge, K.12
Gertz, B.J.13
-
25
-
-
0036604223
-
Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869: A randomized controlled trial
-
DOI 10.1002/cncr.10516
-
Van Belle S, Lichinitser MR, Navari RM et al. Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869. Cancer 94, 3032-3041 (2002). (Pubitemid 34547705)
-
(2002)
Cancer
, vol.94
, Issue.11
, pp. 3032-3041
-
-
Van Belle, S.1
Lichinitser, M.R.2
Navari, R.M.3
Garin, A.M.4
Decramer, M.L.A.5
Riviere, A.6
Thant, M.7
Brestan, E.8
Bui, B.9
Eldridge, K.10
De Smet, M.11
Michiels, N.12
Reinhardt, R.R.13
Carides, A.D.14
Evans, J.K.15
Gertz, B.J.16
-
26
-
-
0037403701
-
1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting
-
DOI 10.1002/cncr.11320
-
Chawla SP, Grunberg SM, Gralla RJ et al. Establishing the dose of the oral NK1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting. Cancer 97, 2290-2300 (2003). (Pubitemid 36444075)
-
(2003)
Cancer
, vol.97
, Issue.9
, pp. 2290-2300
-
-
Chawla, S.P.1
Grunberg, S.M.2
Gralla, R.J.3
Hesketh, P.J.4
Rittenberg, C.5
Elmer, M.E.6
Schmidt, C.7
Taylor, A.8
Carides, A.D.9
Evans, J.K.10
Horgan, K.J.11
-
27
-
-
77952480785
-
Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: A randomized, double-blind study
-
Rapoport BL, Jordan K, Boice JA et al. Aprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with a broad range of moderately emetogenic chemotherapies and tumor types: A randomized, double-blind study. Support Care Cancer 18, 423-431 (2010).
-
(2010)
Support Care Cancer
, vol.18
, pp. 423-431
-
-
Rapoport, B.L.1
Jordan, K.2
Boice, J.A.3
-
28
-
-
33646890831
-
Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment
-
DOI 10.1093/annonc/mdl019
-
Schmoll HJ, Aapro MS, Poli-Bigelli S et al. Comparison of an aprepitant regimen with a multiple-day ondansetron regimen, both with dexamethasone, for antiemetic efficacy in high-dose cisplatin treatment. Ann. Oncol. 17, 1000-1006 (2006). (Pubitemid 43778994)
-
(2006)
Annals of Oncology
, vol.17
, Issue.6
, pp. 1000-1006
-
-
Schmoll, H.J.1
Aapro, M.S.2
Poli-Bigelli, S.3
Kim, H.-K.4
Park, K.5
Jordan, K.6
Von Pawel, J.7
Giezek, H.8
Ahmed, T.9
Chan, C.Y.10
-
29
-
-
79955017477
-
Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: Randomized, double-blind study protocol - EASE
-
Only Phase III fosaprepitant trial and, moreover, the largest antiemetic trial conducted to date
-
Grunberg S, Chua D, Maru A et al. Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with cisplatin therapy: Randomized, double-blind study protocol - EASE. J. Clin. Oncol. 29, 1495-1501 (2011). .. Only Phase III fosaprepitant trial and, moreover, the largest antiemetic trial conducted to date.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1495-1501
-
-
Grunberg, S.1
Chua, D.2
Maru, A.3
-
30
-
-
1642513757
-
1 antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: A combined analysis of two randomised, placebo-controlled phase III clinical trials
-
DOI 10.1016/j.ejca.2003.08.028
-
de Wit R, Herrstedt J, Rapoport B et al. The oral NK(1) antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: A combined analysis of two randomised, placebo-controlled Phase III clinical trials. Eur. J. Cancer 40, 403-410 (2004). (Pubitemid 38121278)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.3
, pp. 403-410
-
-
De Wit, R.1
Herrstedt, J.2
Rapoport, B.3
Carides, A.D.4
Guoguang-Ma, J.5
Elmer, M.6
Schmidt, C.7
Evans, J.K.8
Horgan, K.J.9
-
31
-
-
25144491991
-
Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy
-
DOI 10.1002/cncr.21343
-
Herrstedt J, Muss HB, Warr DG et al. Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and emesis over multiple cycles of moderately emetogenic chemotherapy. Cancer 104, 1548-1555 (2005). (Pubitemid 41356171)
-
(2005)
Cancer
, vol.104
, Issue.7
, pp. 1548-1555
-
-
Herrstedt, J.1
Muss, H.B.2
Warr, D.G.3
Hesketh, P.J.4
Eisenberg, P.D.5
Raftopoulos, H.6
Grunberg, S.M.7
Gabriel, M.8
Rodgers, A.9
Hustad, C.M.10
Horgan, K.J.11
Skobieranda, F.12
-
32
-
-
79955423394
-
Safety evaluation of aprepitant for the prevention of chemotherapy-induced nausea and vomiting
-
Ruhlmann CH, Herrstedt J. Safety evaluation of aprepitant for the prevention of chemotherapy-induced nausea and vomiting. Expert Opin. Drug Saf. 10, 449-462 (2011).
-
(2011)
Expert Opin. Drug Saf
, vol.10
, pp. 449-462
-
-
Ruhlmann, C.H.1
Herrstedt, J.2
-
33
-
-
0037757975
-
1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone
-
DOI 10.1016/S0009-9236(03)00066-3
-
McCrea JB, Majumdar AK, Goldberg MR et al. Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone. Clin. Pharmacol. Ther. 74, 17-24 (2003). (Pubitemid 36776172)
-
(2003)
Clinical Pharmacology and Therapeutics
, vol.74
, Issue.1
, pp. 17-24
-
-
McCrea, J.B.1
Majumdar, A.K.2
Goldberg, M.R.3
Iwamoto, M.4
Gargano, C.5
Panebianco, D.L.6
Hesney, M.7
Lines, C.R.8
Petty, K.J.9
Deutsch, P.J.10
Murphy, M.G.11
Gottesdiener, K.M.12
Goldwater, D.R.13
Blum, R.A.14
-
34
-
-
82955194849
-
Pharmacokinetics of oral dexamethasone and midazolam when administered with single-dose intravenous 150 mg fosaprepitant in healthy adult subjects
-
Marbury TC, Ngo PL, Shadle CR et al. Pharmacokinetics of oral dexamethasone and midazolam when administered with single-dose intravenous 150 mg fosaprepitant in healthy adult subjects. J. Clin. Pharmacol. 51(12), 1712-1720 (2011).
-
(2011)
J. Clin. Pharmacol
, vol.51
, Issue.12
, pp. 1712-1720
-
-
Marbury, T.C.1
Ngo, P.L.2
Shadle, C.R.3
-
35
-
-
27644482810
-
Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin
-
DOI 10.1007/s00228-005-0907-8
-
Depre M, Van HA, Oeyen M et al. Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin. Eur. J. Clin. Pharmacol. 61, 341-346 (2005). (Pubitemid 41569307)
-
(2005)
European Journal of Clinical Pharmacology
, vol.61
, Issue.5-6
, pp. 341-346
-
-
Depre, M.1
Van Hecken, A.2
Oeyen, M.3
De Lepeleire, I.4
Laethem, T.5
Rothenberg, P.6
Petty, K.J.7
Majumdar, A.8
Crumley, T.9
Panebianco, D.10
Bergman, A.11
De Hoon, J.N.12
-
36
-
-
73149083276
-
Phase II trial results with the novel neurokinin-1 receptor antagonist casopitant in combination with ondansetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in cancer patients receiving moderately emetogenic chemotherapy
-
Arpornwirat W, Albert I, Hansen VL et al. Phase II trial results with the novel neurokinin-1 receptor antagonist casopitant in combination with ondansetron and dexamethasone for the prevention of chemotherapy-induced nausea and vomiting in cancer patients receiving moderately emetogenic chemotherapy. Cancer 115, 5807-5816 (2009).
-
(2009)
Cancer
, vol.115
, pp. 5807-5816
-
-
Arpornwirat, W.1
Albert, I.2
Hansen, V.L.3
-
37
-
-
71049145217
-
Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting
-
Roila F, Rolski J, Ramlau R et al. Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting. Ann. Oncol. 20, 1867-1873 (2009).
-
(2009)
Ann. Oncol
, vol.20
, pp. 1867-1873
-
-
Roila, F.1
Rolski, J.2
Ramlau, R.3
-
38
-
-
84856937512
-
The co-administration of the NK1 receptor antagonist netupitant with palonosetron and dexamethasone reduces cisplatin-induced acute and delayed emesis in ferrets
-
Rudd J, Ngan MP, Cantoreggi S, Pietra C. The co-administration of the NK1 receptor antagonist netupitant with palonosetron and dexamethasone reduces cisplatin-induced acute and delayed emesis in ferrets. Support Care Cancer 19(Suppl. 2), S155 (2011).
-
(2011)
Support Care Cancer
, vol.19
, Issue.SUPPL. 2
-
-
Rudd, J.1
Ngan, M.P.2
Cantoreggi, S.3
Pietra, C.4
-
39
-
-
84863446959
-
Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy
-
doi:10.1007/s00520-011-1180-2 ( Epub ahead of print
-
Hesketh PJ, Sanz-Altamira P, Bushey J, and Hesketh AM. Prospective evaluation of the incidence of delayed nausea and vomiting in patients with colorectal cancer receiving oxaliplatin-based chemotherapy. Support Care Cancer doi:10.1007/s00520-011-1180-2 (2011) (Epub ahead of print).
-
(2011)
Support Care Cancer
-
-
Hesketh, P.J.1
Sanz-Altamira, P.2
Bushey, J.3
Hesketh, A.M.4
-
40
-
-
83555172573
-
Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy
-
Hesketh PJ, Bosnjak SM, Nikolic V, Rapoport B. Incidence of delayed nausea and vomiting in patients with colorectal cancer receiving irinotecan-based chemotherapy. Support Care Cancer 19, 2063-2066 (2011).
-
(2011)
Support Care Cancer
, vol.19
, pp. 2063-2066
-
-
Hesketh, P.J.1
Bosnjak, S.M.2
Nikolic, V.3
Rapoport, B.4
-
41
-
-
84856855079
-
Single-dose intravenous casopitant in combination with ondansetron and dexamethasone for the prevention of oxaliplatin-induced nausea and vomiting: A multicenter, randomized, double-blind, active-controlled, two arm, parallel group study
-
doi:10.1007/s00520-011-1235-4 ( Epub ahead of print
-
Hesketh PJ, Wright O, Rosati G et al. Single-dose intravenous casopitant in combination with ondansetron and dexamethasone for the prevention of oxaliplatin-induced nausea and vomiting: A multicenter, randomized, double-blind, active-controlled, two arm, parallel group study. Support Care Cancer doi:10.1007/s00520-011-1235-4 (2011) (Epub ahead of print).
-
(2011)
Support Care Cancer
-
-
Hesketh, P.J.1
Wright, O.2
Rosati, G.3
-
42
-
-
0024994618
-
The natural course of emesis after carboplatin treatment
-
Martin M, Diaz-Rubio E, Sánshez A, Almenarez J, Lopez-Vega M. The natural course of emesis after carboplatin treatment. Acta. Oncol. 29, 593-595 (1990). (Pubitemid 20294735)
-
(1990)
Acta Oncologica
, vol.29
, Issue.5
, pp. 593-595
-
-
Martin, M.1
Diaz-Rubio, E.2
Sanchez, A.3
Almenarez, J.4
Lopez-Vega, J.M.5
|