Evaluation of anti cancer activity of polyherbal formulation

International Journal of Cancer Research

Volumn 8, Issue 1, 2012, Pages 27-36

  Savjiyani, M V ^a   Dave, H ^b   Trivedi, S ^b   Rachchh, M A ^a   Gokani, R H ^a  

^a S J Thakkar Pharmacy College   (India)

^b GUJARAT CANCER AND RESEARCH INSTITUTE   (India)

Author keywords

Caco 2; Cell death detection ELISA PLUS; MCF 7; MTT assay; Polyherbal formulation

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; FLAVANOID; FLUOROURACIL; HERBACEOUS AGENT; PHENOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BARK; BAUHINIA VARIEGATA; BREAST TUMOR; CARCINOMA CELL; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA FRAGMENTATION; DRUG EFFICACY; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; INDIGOFERA TINCTORIA; NONHUMAN; ORYXYLUM INDICUM; PLANT; PLANT LEAF; PLANT STEM; RAT; TECOMELLA UNDULATA; TREATMENT RESPONSE; TUMOR VOLUME;

EID: 84856899811     PISSN: 18119727     EISSN: 18119735     Source Type: Journal    
DOI: 10.3923/ijcr.2012.27.36     Document Type: Article

References (31)

1. Adesegun, S.A., NA. Elechi and H.A.B. Coker, 2007. Antioxidant power of Macaranga barteri leaf. Am. J. Food Technol, 2: 543-549.
2. Aini, A.S.N., A. Merrina, J. Stanslas and S. Sreeramanan, 2008. Cytotoxic potential on breast cancer cells using selected forest species found in Malaysia. Int. J. Cancer Res., 4: 103-109.
3. Anonymous, 2002. WHO Guidelines. 1st Edn., A.I.T.B.S. Publishers and Distributors, New Delhi, ISBN: 9789241594448, pages: 45-46.
4. Anonymous, 2007. The Wealth of India. Publications and Information Directorate, CSIR, New Delhi, ISBN: 81-85038-03-01, Pages: 205.
5. Anonymous, 2008. Cancer: Report of WHO study group on cancer Geneva. WHO. Ashkenazi, A. and V.M. Dixit, 1998. Death receptors: Dignalling and modulation. Science, 281: 1305-1308.
6. Bahorun, T., B. Gressier, F. Trotin, C. Brunet and T. Dine et al., 1996. Oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations. Arzneimittle Forshing, 46: 1086-1089.
7. Bisht, V.K., J.S. Negi, A.K. Bhandari and R.C. Sundriyal, 2011. Anti-cancerous plants of Uttarakhand Himalaya: A review. Int. J. Cancer Res., 7: 192-208.
8. Dashora, N., V. Sodde, K.S. Prabhu and R. Lobo, 2011. In vitro cytotoxic activity of Dendrophthoe falcata on human breast adenocarcinoma cells-MCF-7. Int. J. Cancer Res., 7: 47-54.
9. Freedman, L., C. Clifford and M. Messina, 1990. Analysis of dietary fat, calories, body weight and the development of mammary tumors in rats and mice: A review. Cancer Res., 50: 5710-5719.
10. Green, D.R. and J.C. Reed, 1998. Mitochondria and apoptosis. Science, 281: 1309-1312.
11. Guzman, R.C, R.C. Osborn, J.C. Bartley and S. Nandi, 1988. Metabolism of 7,12-dimethylbenz [a] anthracene by mouse mammary epithelial cells cultured serum-free inside collagen gelsa. Cancer Lett., 30: 123-132.
12. Hirano, T., K. Oka and M. Akiba, 1989. Antiproliferative effect of synthetic and naturally occurring flavonoids on tumour cells of human carcinoma cells lines. Res. Commun. Chem. Pathol. Pharmacol., 64: 69-78.
13. Karneswaran, T.R. and R. Ramanibai, 2008. The antiproliferative activity of flavanoidal fraction of Indigo fera tinctorial, through cell cycle arrest and apoptotic pathway in A-549 cells. J. Boil. Sci, 8: 584-590.
14. Khorshid, FA., S.A. Rahimaldeen and J.S. Al-Amri, 2011. Apoptosis study on the effect of PMF on different cancer cells. Int. J. Biol. Chem., 5: 150-155.
15. Kumar, R.A., V. Rajkumar, G. Guha and M. Lazar, 2010. Therapeutic potential of Oroxylum indicumharh. extract. Chin. J. Nat. Med., 8: 121-126.
16. McFadden, D.W., D.R. Riggs, B.J. Jackson and V.D. Linda, 2003. Keyhole limpet hemocyanin, a novel immune stimulant with promising anticancer activity in Barrett's esophageal adenocarcinoma. Am. J. Surg., 186: 552-555.
17. Nesaretnam, K, E. Hales, M. Sohail, T. Krausz and P. Darbre, 1998. 3,3',4,4'-tetrachlorobiphenyl (TCB) can enhance DMBA-induced mammary carcinogenesis in the rat. Eur. J. Cancer, 34: 389-393.
18. Pandey, S. and R.C. Agrawal, 2009. Effect of Bauhinia variegataharh. extract on DMBA-induced mouse skin carcinogenesis, a preliminary study. Global. J. Pharmacol., 3: 158-162.
19. Pereira, P.C., A.F. Vicente, M.F. Mesquita and A.S. Cabrita, 2011. The role of Phaseolus vulgaris in DMBA-induced sprague-dawley rat mammary carcinomas. Int. J. Cancer Res., 7: 125-134.
20. Prajapati, N.D., S.S. Purohit, A.K. Sharma and T. Kumar, 2007. Medicinal Plants A to Z. Agrobios, New York, pp: 352-356.
21. Ravi, A., A. Malhka, V. Sama, A. Begum, R.S. Khan and B.M. Reddy, 2011. Antiproliferative activity and standardization of Tecomella undulata bark extract on K562 cells. J. Ethnopharmacol., 10.1016/j.jep.2011.07.067
22. Robert, B. and T. Henry, 2007. Medicinal Plants. Asiatic Publishing House, Delhi, India, pp: 405-407.
23. Roy, M., S. Chakraborty, M. Siddiqi and R.K. Bhattacharya, 2002. Induction of apoptosis in tumor cells by natural phenolic compounds. Asian Pac. J. Cancer Prev., 3: 61-67.
24. Sammour, R.H. and A.R. El-Shanshoury, 1992. Antimicrobial activity of legume seed proteins. Bot. Bull. Acad. Sin., 33: 185-190.
25. Sasaki, Y.F., S. Kawaguchi, A. Kamaya, M. Ohshita and K. Kabasawa et al., 2002. The comet assay with 8 mouse organs: Results with 39 currently used food additives. Mutat. Res./Gen. Toxicol. Envrion. Mutagenesis, 519: 103-119.
26. Stennicke, H.R. and G.S. Salvesen, 1998. Properties of the caspases. Biochem. Biophys Acta., 1387: 17-31.
27. Sunilson, J.A.J., G. Rejitha, K. Anandarajagopal, A. Das, M. Muthappan and P. Promwichit, 2009. Cytotoxic effect of Cayratia carnosa leaves on human breast cancer cell lines. Int. J. Cancer Res, 5: 115-122.
28. Thompson, C.B, 1995. Apoptosis in the pathogenesis and treatment of diseases. Science, 267: 1456-1462.
29. Tripathi, K.D, 2003. Anticancer Drugs. In: Essentials of Medical Pharmacology, Tripathi, K.D. (Ed.). Jaypee Brothers Medical Publishers, New Delhi, pp: 769-785.
30. Uddm, K, A. Sayeed, A. Islam, A.A. Rahman, A. All, G.R.M.A.M. Khan and M.G. Sadik, 2003. Purification, characterization and cytotoxic activity of two flavonoids from Oroxylum indicum Vent. (Bignoniaceae). Asian J. Plant Sci, 2: 515-518.
31. Welsch, C.W, 1987. Implications of mammary tumorigenesis by dietary fat: Review of potential mechanisms. Am. J. Clm. Nutr, 45: 192-202.