Treatment of epidemic keratoconjunctivitis with 2% povidone-iodine: A pilot study

Journal of Ocular Pharmacology and Therapeutics

Volumn 28, Issue 1, 2012, Pages 53-58

  Trinavarat, Adisak ^a   Atchaneeyasakul, La Ongsri ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

POVIDONE IODINE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONVALESCENCE; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; HUMAN; KERATOCONJUNCTIVITIS; KERATOCONJUNCTIVITIS EPIDEMICA; MALE; SCHOOL CHILD; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ADMINISTRATION, OPHTHALMIC; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFECTIVE AGENTS, LOCAL; CHILD; FEMALE; HUMANS; KERATOCONJUNCTIVITIS; MALE; MIDDLE AGED; PILOT PROJECTS; POVIDONE-IODINE; PROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84856875031     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2011.0082     Document Type: Article

References (15)

1. Isenberg, S.J., Apt, L., and Campeas, D. Ocular applications of povidone-iodine. Dermatology 204 Suppl 1:92-95, 2002. (Pubitemid 34518745)
2. Kawana, R., Kitamura, T., Nakagomi, O., et al. Inactivation of human viruses by povidone-iodine in comparison with other antiseptics. Dermatology 195 Suppl 2:29-35, 1997. (Pubitemid 27487597)
3. Waring, G.O.E., Laibson, P.R., Satz, J.E., and Joseph, N.H. Use of vidarabine in epidemic keratoconjunctivitis due to adeno-virus types 3, 7, 8, and 19. Am. J. Ophthalmol. 82:781-785, 1976.
4. Ward, J.B., Siojo, L.G., and Waller, S.G. A prospective, masked clinical trial of trifluridine, dexamethasone, and artificial tears in the treatment of epidemic keratoconjunctivi-tis. Cornea 12:216-221, 1993. (Pubitemid 23137862)
5. Kinchington, P.R., Romanowski, E.G., and Jerold Gordon, Y. Prospects for adenovirus antivirals. J. Antimicrob. Chemother. 55:424-429, 2005. (Pubitemid 40542579)
6. Hillenkamp, J. Reinhard, T., Ross, R.S., et al. The effects of cidofovir 1% with and without cyclosporin a 1% as a topical treatment of acute adenoviral keratoconjunctivitis: a controlled clinical pilot study. Ophthalmology 109:845-850, 2002. (Pubitemid 34465214)
7. Wilhelmus, K.R., Dunkel, E.C., and Herson, J. Topical human fibroblast interferon for acute adenoviral conjunctivitis. Graefes Arch. Clin. Exp. Ophthalmol. 225:461-464, 1987. (Pubitemid 17153723)
8. Teuchner, B., Nagl, M., Schidlbauer, A. et al. Tolerability and efficacy of N-chlorotaurine in epidemic keratoconjunctivi-tis-a double-blind, randomized, phase-2 clinical trial. J. Ocul. Pharmacol. Ther. 21:157-165, 2005. (Pubitemid 40577971)
9. Romanowski, E.G., Yates, K.A., and Gordon, Y.J. Topical cor-ticosteroids of limited potency promote adenovirus replication in theAd5/NZWrabbit ocularmodel.Cornea21:289-291, 2002. (Pubitemid 34250607)
10. Gordon, Y.J., Araullo-Cruz, T., and Romanowski, E.G. The effects of topical nonsteroidal anti-inflammatory drugs on adenoviral replication. Arch. Ophthalmol. 116:900-905, 1998. (Pubitemid 28554780)
11. Hutter, H. Epidemic keratoconjunctivitis: treatment results during an epidemic. Klin Monbl Augenheilkd. 197:214-217, 1990.
12. Abel, R., and Abel, A.D. Use of povidone-iodine in treatment of presumptive adenoviral conjunctivitis. Ann. Oph-thalmol. 30:341-343, 1998. (Pubitemid 28527555)
13. Isenberg, S.J., Apt, L., Valenton, M., et al. A controlled trial of povidone-iodine to treat infectious conjunctivitis in children. Am. J. Ophthalmol. 134:681-688, 2002. (Pubitemid 35300386)
14. Trinavarat, A., Atchaneeyasakul, L.O., Nopmaneejumruslers, C., and Inson, K. Reduction of endophthalmitis rate after cataract surgery with preoperative 5% povidone-iodine. Dermatology 212 Suppl 1:35-40, 2006.
15. Pelletier, J.S., Stewart, K., Trattler, W. et al. A combination povidone-iodine 0.4%/dexamethasone 0.1% ophthalmic suspension in the treatment of adenoviral conjunctivitis. Adv. Ther. 26:776-783, 2009.