Transmissible gastroenteritis coronavirus RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles

Journal of Virology

Volumn 86, Issue 2, 2012, Pages 1261-1266

  Nogales, Aitor ^a   Márquez Jurado, Silvia ^a   Galán, Carmen ^a,b   Enjuanes, Luis ^a   Almazán, Fernando ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 8; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE TEST; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIRION; VIRUS PARTICLE; WESTERN BLOTTING;

ANIMALS; GASTROENTERITIS, TRANSMISSIBLE, OF SWINE; RNA REPLICASE; SWINE; TRANSMISSIBLE GASTROENTERITIS VIRUS; VIRAL NONSTRUCTURAL PROTEINS; VIRION; VIRUS ASSEMBLY; VIRUS REPLICATION;

CORONAVIRUS; TRANSMISSIBLE GASTROENTERITIS VIRUS;

EID: 84856860892     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06428-11     Document Type: Article

References (28)

1. Almazán F, Galán C, Enjuanes L. 2004. The nucleoprotein is required for efficient coronavirus genome replication. J. Virol. 78:12683-12688.
2. Bremer A, Häner M, Aebi U. 1998. Negative staining, p 277-284. In Celis JE (ed), Cell biology, a laboratory handbook, 2nd ed, vol 3. Academic Press, San Diego, CA.
3. Brockway SM, Clay CT, Lu XT, Denison MR. 2003. Characterization of the expression, intracellular localization, and replication complex association of the putative mouse hepatitis virus RNA-dependent RNA polymerase. J. Virol. 77:10515-10527.
4. Carstens EB. 2010. Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2009). Arch. Virol. 155:133-146.
5. Correa I, Jiménez G, Suñé C, Bullido MJ, Enjuanes L. 1988. Antigenic structure of the E2 glycoprotein from transmissible gastroenteritis coronavirus. Virus Res. 10:77-94.
6. de Groot RJ, et al. Coronaviridae, p 774-796. In Fauquet CM, Mayo MA, Maniloff J, Desselberg U, KingA(ed), Virus taxonomy: ninth report of the International Committee on Taxonomy of Viruses. Academic Press, San Diego, CA.
7. Enjuanes L, Almazán F, Sola I, Zuñiga S. 2006. Biochemical aspects of coronavirus replication and virus-host interaction. Annu. Rev. Microbiol. 60:211-230.
8. Enjuanes L, Sola I, Zuñiga S, Almazán F. 2008. Coronavirus replication and interaction with host, p 149-202. In Mettenleiter TC, Sobrino F (ed), Animal viruses. Molecular biology. Caister Academic Press, Norfolk, United Kingdom.
9. Galán C, et al. 2009. Host cell proteins interacting with the 3= end of TGEV coronavirus genome influence virus replication. Virology 391:304-314.
10. Gorbalenya AE, Koonin EV, Donchenko AP, Blinov VM. 1989. Coronavirus genome: prediction of putative functional domains in the nonstructural polyprotein by comparative amino acid sequence analysis. Nucleic Acids Res. 17:4847-4861.
11. Gosert R, Kanjanahaluethai A, Egger D, Bienz K, Baker SC. 2002. RNA replication of mouse hepatitis virus takes place at double-membrane vesicles. J. Virol. 76:3697-3708.
12. Jiménez G, Correa I, Melgosa MP, Bullido MJ, Enjuanes L. 1986. Critical epitopes in transmissible gastroenteritis virus neutralization. J. Virol. 60:131-139.
13. Knoops K, et al. 2008. SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum. PLoS Biol. 6:1957-1974.
14. Kong Q, et al. 2010. Proteomic analysis of purified coronavirus infectious bronchitis virus particles. Proteome Sci. 8:29.
15. Martín Alonso JM, et al. 1992. Antigenic structure of transmissible gastroenteritis virus nucleoprotein. Virology 188:168-174.
16. Masters PS. 2006. The molecular biology of coronaviruses. Adv. Virus Res. 66:193-292.
17. Neuman BW, et al. 2008. Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3. J. Virol. 82:5279-5294.
18. Nogales A, et al. 2011. Immunogenic characterization and epitope mapping of transmissible gastroenteritis virus RNA dependent RNA polymerase. J. Virol. Methods 175:7-13.
19. Ortego J, Ceriani JE, Patiño C, Plana J, Enjuanes L. 2007. Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway. Virology 368:296-308.
20. Risco C, Antón IM, Enjuanes L, Carrascosa JL. 1996. The transmissible gastroenteritis coronavirus contains a spherical core shell consisting ofM and N proteins. J. Virol. 70:4773-4777.
21. Risco C, et al. 1995. Membrane protein molecules of transmissible gastroenteritis coronavirus also expose the carboxy-terminal region on the external surface of the virion. J. Virol. 69:5269-5277.
22. Rodriguez MJ, et al. 2001. Identification of an immunodominant epitope in the C terminus of glycoprotein 5 of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 82:995-999.
23. Schelle B, Karl N, Ludewig B, Siddell SG, Thiel V. 2005. Selective replication of coronavirus genomes that express nucleocapsid protein. J. Virol. 79:6620-6630.
24. Snijder EJ, et al. 2006. Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. J. Virol. 80:5927-5940.
25. Sola I, Mateos-Gomez PA, Almazán F, Zuñiga S, Enjuanes L. 2011. RNA-RNA and RNA-protein interactions in coronavirus replication and transcription. RNA Biol. 8:1-13.
26. Ziebuhr J. 2005. The coronavirus replicase, p 57-94. In Enjuanes L (ed), Coronavirus replication and reverse genetics, vol 287. Springer-Verlag, Berlin, Germany.
27. Ziebuhr J, Snijder EJ, Gorbalenya AE. 2000. Virus-encoded proteinases and proteolytic processing in the Nidovirales. J. Gen. Virol. 81:853-879.
28. Zúñiga S, et al. 2010. Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription. J. Virol. 84: 2169-2175.