Point-of-care urine antigen screening tests for tuberculosis and cryptococcosis: Potential for mortality reduction in antiretroviral treatment programs in Africa

Clinical Infectious Diseases

Volumn 54, Issue 5, 2012, Pages 739-740

  Lawn, Stephen D ^a,b   Wood, Robin ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ANTIRETROVIRUS AGENT; LIPOARABINOMANNAN;

AFRICA; BACTERIUM CULTURE; BLOOD SAMPLING; CD4 LYMPHOCYTE COUNT; CRYPTOCOCCAL MENINGITIS; DIAGNOSTIC ACCURACY; DISEASE ASSOCIATION; DRUG PROGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; HEALTH PROGRAM; HOSPITAL ADMISSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; MORTALITY; MYCOBACTERIUM TUBERCULOSIS; POINT OF CARE TESTING; PRIORITY JOURNAL; SCREENING TEST; STREPTOCOCCUS PNEUMONIA; TUBERCULOSIS; URINALYSIS;

ANTIGENS, FUNGAL; CRYPTOCOCCUS NEOFORMANS; FEMALE; HIV INFECTIONS; HUMANS; IMMUNOASSAY; MALE; MENINGITIS, CRYPTOCOCCAL; POLYSACCHARIDES;

EID: 84856845215     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir908     Document Type: Letter

References (8)

1. Lawn SD, Harries AD, Anglaret X, Myer L, Wood R. Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa. AIDS 2008; 22:1897-908.
2. Lawn SD, Harries AD, Wood R. Strategies to reduce early morbidity and mortality in adults receiving antiretroviral therapy in resourcelimited settings. Curr Opin HIV AIDS 2010; 5:18-26.
3. Jarvis JN, Lawn SD, Vogt M, Bangani N, Wood R, Harrison TS. Screening for cryptococcal antigenemia in patients accessing an antiretroviral treatment program in South Africa. Clin Infect Dis 2009; 48:856-62.
4. Lawn SD, Kranzer K, Edwards DJ, McNally M, Bekker LG, Wood R. Tuberculosis during the first year of antiretroviral therapy in a South African cohort using an intensive pretreatment screening strategy. AIDS 2010; 24:1323-8.
5. Jarvis JN, Percival A, Bauman S, et al. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin Infect Dis 2011; 53:1019-23.
6. Lawn SD, Kerkhoff AD, Vogt M, Wood R. Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive study. Lancet Infect Dis 2011; e-pub ahead of print.
7. Lawn SD, Edwards DJ, Kranzer K, Vogt M, Bekker LG, Wood R. Urine lipoarabinomannan assay for tuberculosis screening before antiretroviral therapy diagnostic yield and association with immune reconstitution disease. AIDS 2009; 23:1875-80.
8. Vernet G, Saha S, Satzke C, et al. Laboratorybased diagnosis of pneumococcal pneumonia: state of the art and unmet needs. Clin Microbiol Infect 2011; 17(Suppl 3): 1-13.