Genetic reevaluation of the Role of F-Box proteins in cyclin D1 degradation

Molecular and Cellular Biology

Volumn 32, Issue 3, 2012, Pages 590-605

  Kanie, Tomoharu ^a,b   Onoyama, Ichiro ^a,b   Matsumoto, Akinobu ^a,b   Yamada, Masanori ^a,b   Nakatsumi, Hirokazu ^a,b   Tateishi, Yuki ^a,b   Yamamura, So ^a,b   Tsunematsu, Ryosuke ^a,b   Matsumoto, Masaki ^a,b   Nakayama, Keiichi I ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CYCLIN D1; F BOX PROTEIN; MESSENGER RNA; PROTEASOME; PROTEIN FBXO31; PROTEIN FBXO4; PROTEIN FBXW8; S PHASE KINASE ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; FEMALE; FIBROBLAST; GENETIC ANALYSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STABILITY; RNA INTERFERENCE; UPREGULATION; WILD TYPE;

ANIMALS; CELL CYCLE; CULLIN PROTEINS; CYCLIN D1; F-BOX PROTEINS; FEMALE; FIBROBLASTS; MALE; MICE; MICE, INBRED C57BL; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; PROTEOLYSIS; RNA INTERFERENCE; S-PHASE KINASE-ASSOCIATED PROTEINS; UBIQUITIN-PROTEIN LIGASE COMPLEXES;

ANIMALIA; MUS;

EID: 84856781262     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.06570-11     Document Type: Article

References (44)

1. 1 cell cycle arrest in response to DNA damage. Cell 102:55-66.
2. Alt JR, Cleveland JL, Hannink M, Diehl JA. 2000. Phosphorylationdependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev. 14:3102-3114.
3. Ang XL, Wade Harper J. 2005. SCF-mediated protein degradation and cell cycle control. Oncogene 24:2860-2870.
4. 1. Genes Dev. 7:812-821.
5. Barbash O, et al. 2008. Mutations in Fbx4 inhibit dimerization of the SCFFbx4 ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell 14:68-78.
6. Bessho Y, et al. 2001. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 15:2642-2647.
7. Blain SW. 2008. Switching cyclin D-Cdk4 kinase activity on and off. Cell Cycle 7:892-898.
8. Buckley MF, et al. 1993. Expression and amplification of cyclin genes in human breast cancer. Oncogene 8:2127-2133.
9. Diehl JA, Cheng M, Roussel MF, Sherr CJ. 1998. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12:3499-3511.
10. Diehl JA, Zindy F, Sherr CJ. 1997. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitinproteasome pathway. Genes Dev. 11:957-972.
11. Fukami-Kobayashi J, Mitsui Y. 1999. Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2. Exp. Cell Res. 246:338-347.
12. Guo Y, et al. 2005. Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene 24:2599-2612.
13. Kip1 on serine 10 is required for its binding to CRM1 and nuclear export. J. Biol. Chem. 277:14355-14358.
14. 1 phase. Nat. Cell Biol. 6:1229-1235.
15. Kim JK, Diehl JA. 2009. Nuclear cyclin D1: an oncogenic driver in human cancer. J. Cell. Physiol. 220:292-296.
16. Kozar K, et al. 2004. Mouse development and cell proliferation in the absence of D-cyclins. Cell 118:477-491.
17. Lee TH, Perrem K, Harper JW, Lu KP, Zhou XZ. 2006. The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance. J. Biol. Chem. 281:759-768.
18. FBX4-αB crystallin complex. Mol. Cell 24:355-366.
19. Malumbres M, et al. 2004. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 118:493-504.
20. 1 cyclins. Cell 71:323-334.
21. Matsushime H, et al. 1994. D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol. 14:2066-2076.
22. 1 phase of the cell cycle. Cell 65:701-713.
23. 1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14:2077-2086.
24. Motokura T, et al. 1991. A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature 350:512-515.
25. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
26. Kip1, polyploidy and centrosome overduplication. EMBO J. 19:2069-2081.
27. Nakayama K, et al. 2004. Skp2-mediated degradation of p27 regulates progression into mitosis. Dev. Cell 6:661-672.
28. Nakayama KI, Nakayama K. 2006. Ubiquitin ligases: cell-cycle control and cancer. Nat. Rev. Cancer 6:369-381.
29. Newman RM, et al. 2004. Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression. J. Biol. Chem. 279:41504-41511.
30. Okabe H, et al. 2006. A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation. PLoS One 1:e128.
31. Pagano M, Theodoras AM, Tam SW, Draetta GF. 1994. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev. 8:1627-1639.
32. Pawar SA, et al. 2010. C/EBPδtargets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression. Proc. Natl. Acad. Sci. U. S. A. 107:9210-9215.
33. Pontano LL, et al. 2008. Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Mol. Cell. Biol. 28:7245-7258.
34. Rappsilber J, Ishihama Y, Mann M. 2003. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 75:663-670.
35. 1 arrest after DNA damage. Nature 459:722-725.
36. Shinozaki H, et al. 1996. Cyclin D1 amplification as a new predictive classification for squamous cell carcinoma of the esophagus, adding gene information. Clin. Cancer Res. 2:1155-1161.
37. Sicinski P, et al. 1995. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 82:621-630.
38. Solomon DA, et al. 2003. Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J. Biol. Chem. 278:30339-30347.
39. Tsunematsu R, et al. 2006. Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. Mol. Cell. Biol. 26:6157-6169.
40. Wang TC, et al. 1994. Mammary hyperplasia and carcinoma in MMTVcyclin D1 transgenic mice. Nature 369:669-671.
41. Wei S, et al. 2008. A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells. J. Biol. Chem. 283:26759-26770.
42. Xu X, et al. 2008. The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation. Mol. Cell 30:403-414.
43. Yang WI, Zukerberg LR, Motokura T, Arnold A, Harris NL. 1994. Cyclin D1 (Bcl-1, PRAD1) protein expression in low-grade B-cell lymphomas and reactive hyperplasia. Am. J. Pathol. 145:86-96.
44. CIP1/WAF1 and cyclin D proteins. Proc. Natl. Acad. Sci. U. S. A. 95:11324-11329.