Insulin secretion and insulin sensitivity on the oral glucose tolerance test (OGTT) in middle-aged Japanese

Endocrine Journal

Volumn 59, Issue 1, 2012, Pages 55-64

  Oka, Rie ^a   Yagi, Kunimasa ^b   Sakurai, Masaru ^c   Nakamura, Koshi ^c   Moriuchi, Tadashi ^a   Miyamoto, Susumu ^b   Kawashiri, Masa aki ^b   Takedaspi Sup, Yoshiyu ^b   Yamagishi, Masakazu ^b  

^a Hokuriku Central Hospital   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Impaired fasting glucose (IFG); Impaired glucose tolerance (IGT); Oral glucose tolerance test (OGTT)

Indexed keywords

GLUCOSE; INSULIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; FOOD DEPRIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; HYPERGLYCEMIA; IMPAIRED FASTING GLUCOSE; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN SENSITIVITY; INSULINOGENIC INDEX; JAPANESE; MALE; MATSUDA INSULIN SENSITIVITY INDEX; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; SCORING SYSTEM; WORKER;

ADULT; AGED; ALGORITHMS; BLOOD GLUCOSE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HOSPITALS, PUBLIC; HUMANS; HYPERGLYCEMIA; INCIDENCE; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; JAPAN; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

EID: 84856775790     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ11-0157     Document Type: Article

References (33)

1. Abdul-Ghani MA, Tripathy D, DeFronzo RA (2006) Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose. Diabetes Care 29: 1130-1139.
2. Polonsky KS, Given BD, Hirsch L, Shapiro ET, Tillil H, Beebe C, et al. (1988) Quantitative study of insulin secretion and clearance in normal and obese subjects. J Clin Invest 81: 435-441.
3. DeFronzo RA, Tobin JD, Andres R (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237: E214-223.
4. Pratley RE, Weyer C (2001) The role of impaired early insulin secretion in the pathogenesis of Type II diabetes mellitus. Diabetologia 44: 929-945.
5. Kosaka K, Kuzuya T, Hagura R, Yoshinaga H (1996) Insulin response to oral glucose load is consistently decreased in established non-insulin-dependent diabe- tes mellitus: the usefulness of decreased early insulin response as a predictor of non-insulin-dependent diabetes mellitus. Diabet Med 13: S109-119.
6. Abdul-Ghani MA, Jenkinson CP, Richardson DK, Tripathy D, DeFronzo RA (2006) Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study. Diabetes 55: 1430-1435.
7. Tripathy D, Carlsson M, Almgren P, Isomaa B, Taskinen MR, Tuomi T, et al. (2000) Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study. Diabetes 49: 975-980.
8. Kim DJ, Lee MS, Kim KW, Lee MK (2001) Insulin secretory dysfunction and insulin resistance in the patho-genesis of korean type 2 diabetes mellitus. Metabolism 50: 590-593.
9. Hanefeld M, Koehler C, Fuecker K, Henkel E, Schaper F, Temelkova-Kurktschiev T (2003) Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose: the risk factor in Impaired Glucose Tolerance for Atherosclerosis and Diabetes study. Diabetes Care 26: 868-874.
10. Nishi Y, Fukushima M, Suzuki H, Mitsui R, Ueda N, Taniguchi A, et al. (2005) Insulin secretion and insulin sensitivity in Japanese subjects with impaired fasting glucose and isolated fasting hyperglycemia. Diabetes Res Clin Pract 70: 46-52.
11. Rhee SY, Woo JT, Chon S, Hwang YC, Oh S, Ahn KJ, et al. (2010) Characteristics of insulin resistance and insulin secretory capacity in Korean subjects with IFG and IGT. Diabetes Res Clin Pract 89: 250-255.
12. Stancakova A, Javorsky M, Kuulasmaa T, Haffner SM, Kuusisto J, Laakso M (2009) Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men. Diabetes 58: 1212-1221.
13. Charbonnel B, Karasik A, Liu J, Wu M, Meininger G (2006) Effcacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone. Diabetes Care 29: 2638-2643.
14. Matsuda M, DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22: 1462-1470.
15. Lorenzo C, Haffner SM, Stancakova A, Laakso M (2010) Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in non-diabetic fnnish offspring of type 2 diabetic individuals. J Clin Endocrinol Metab 95: 5082-5090.
16. Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, et al. (2003) Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26: 3160-3167.
17. DeFronzo RA, Matsuda M (2010) Reduced time points to calculate the composite index. Diabetes Care 33: e93.
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
19. Retnakaran R, Qi Y, Goran MI, Hamilton JK (2009) Evaluation of proposed oral disposition index measures in relation to the actual disposition index. Diabet Med 26: 1198-1203.
20. Sato Y, Komatsu M, Katakura M, Ohfusa H, Yamada S, Yamauchi K, et al. (2002) Diminution of early insulin response to glucose in subjects with normal but minimally elevated fasting plasma glucose. Evidence for early beta-cell dysfunction. Diabet Med 19: 566-571.
21. Abdul-Ghani MA, Matsuda M, Jani R, Jenkinson CP, Coletta DK, Kaku K, et al. (2008) The relationship between fasting hyperglycemia and insulin secretion in subjects with normal or impaired glucose tolerance. Am J Physiol Endocrinol Metab 295: E401-406.
22. Festa A, D'Agostino R, Jr., Hanley AJ, Karter AJ, Saad MF, Haffner SM (2004) Differences in insulin resistance in nondiabetic subjects with isolated impaired glucose tolerance or isolated impaired fasting glucose. Diabetes 53: 1549-1555.
23. Godsland IF, Jeffs JA, Johnston DG (2004) Loss of beta cell function as fasting glucose increases in the non-diabetic range. Diabetologia 47: 1157-1166.
24. DeFronzo RA, Ferrannini E, Simonson DC (1989) Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism 38: 387-395.
25. Meyer C DJ, Nadkarni V, Gerich J (1998) Effects of physiological hyperinsulinemia on systemic, renal and hepatic substrate metabolism. Am J Physiol 275: F915-F921.
26. DeFronzo RA, Ferrannini E, Hendler R, Wahren J, Felig P (1978) Infuence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange. Proc Natl Acad Sci U S A 75: 5173-5177.
27. Bratusch-Marrain PR (1984) [The euglycemic insulin and hyperglycemic clamp technic. Methods for the determination of insulin sensitivity of tissues and glucose sensitivity of the B cell. A review]. Infusionsther Klin Ernahr 11: 4-10 (In German).
28. Meyer C, Pimenta W, Woerle HJ, Van Haeften T, Szoke E, Mitrakou A, et al. (2006) Different mechanisms for impaired fasting glucose and impaired postprandial glucose tolerance in humans. Diabetes Care 29: 1909-1914.
29. Weyer C, Bogardus C, Pratley RE (1999) Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose tolerance. Diabetes 48: 2197-2203.
30. Utzschneider KM, Prigeon RL, Faulenbach MV, Tong J, Carr DB, Boyko EJ, et al. (2009) Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels. Diabetes Care 32: 335-341.
31. Retnakaran R, Shen S, Hanley AJ, Vuksan V, Hamilton JK, Zinman B (2008) Hyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test. Obesity (Silver Spring) 16: 1901-1907.
32. Utzschneider KM, Prigeon RL, Tong J, Gerchman F, Carr DB, Zraika S, et al. (2007) Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studies. Diabetologia 50: 2516-2525.
33. Abdul-Ghani MA, Williams K, DeFronzo R, Stern M (2006) Risk of progression to type 2 diabetes based on relationship between postload plasma glucose and fasting plasma glucose. Diabetes Care 29: 1613-1618.