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Volumn 74, Issue 5, 2011, Pages 352-356

A safety study of retinal toxicity after serial intravitreal injections of infliximab in rabbits eyes;Estudo de toxicidade retiniana após injeções intravítreas seriadas de infliximabe em olhos de coelhos

Author keywords

Animals; Antibodies, monoclonal administration dosage; Choroid diseases drug therapy; Electroretinography; Injections, intravenous; Macular degeneration; Rabbits; Retina; Retinal diseases drug therapy; Tumor necrosis factor alpha

Indexed keywords

ANTIINFLAMMATORY AGENT; INFLIXIMAB; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

EID: 84856770408     PISSN: 00042749     EISSN: 16782925     Source Type: Journal    
DOI: 10.1590/S0004-27492011000500009     Document Type: Article
Times cited : (9)

References (30)
  • 1
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: integrating mammalian biology
    • Locksley RM, Killeen N, Leonardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001;104(4):487-501.
    • (2001) Cell , vol.104 , Issue.4 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Leonardo, M.J.3
  • 2
    • 7044228789 scopus 로고    scopus 로고
    • A central role for inflammation in the pathogenesis of diabetic retinopathy
    • Joussen AM, Poulaki V, Le ML, Koizumi K, Janicki H, Schraemeyer U, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J. 2004;18(12):1450-2.
    • (2004) FASEB J , vol.18 , Issue.12 , pp. 1450-1452
    • Joussen, A.M.1    Poulaki, V.2    Le, M.L.3    Koizumi, K.4    Janicki, H.5    Schraemeyer, U.6
  • 3
    • 0030065211 scopus 로고    scopus 로고
    • Distribution of TNF alpha and its reactive vascular adhesion molecules in fibrovascular membranes of proliferative diabetic retinopathy
    • Limb GA, Chignell AH, Green W, LeRoy F, Dumonde DC. Distribution of TNF alpha and its reactive vascular adhesion molecules in fibrovascular membranes of proliferative diabetic retinopathy. Br J Ophthalmol. 1996:80(2):168-73.
    • (1996) Br J Ophthalmol , vol.80 , Issue.2 , pp. 168-173
    • Limb, G.A.1    Chignell, A.H.2    Green, W.3    LeRoy, F.4    Dumonde, D.C.5
  • 4
    • 0031712272 scopus 로고    scopus 로고
    • Detection of vascular endothelial growth factor and tumor necrosis factor alpha in epiretinal membranes of proliferative diabetic retinopathy, proliferative vitreoretinopathy and macular pucker
    • Armstrong D, Augustin AJ, Spengler R, Al-Jada A, Nikola T, Grus F, et al. Detection of vascular endothelial growth factor and tumor necrosis factor alpha in epiretinal membranes of proliferative diabetic retinopathy, proliferative vitreoretinopathy and macular pucker. Ophthalmologica. 1998;212(6):410-4.
    • (1998) Ophthalmologica , vol.212 , Issue.6 , pp. 410-414
    • Armstrong, D.1    Augustin, A.J.2    Spengler, R.3    Al-Jada, A.4    Nikola, T.5    Grus, F.6
  • 5
    • 33750428239 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha reduces laser-induced choroidal neovascularization
    • Shi X, Semkova I, Müther PS, Dell S, Kociok N, Joussen AM. Inhibition of TNF-alpha reduces laser-induced choroidal neovascularization. Exp Eye Res. 2006;83(6):1325-34.
    • (2006) Exp Eye Res , vol.83 , Issue.6 , pp. 1325-1334
    • Shi, X.1    Semkova, I.2    Müther, P.S.3    Dell, S.4    Kociok, N.5    Joussen, A.M.6
  • 6
    • 4544290245 scopus 로고    scopus 로고
    • The role of tumor necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU)
    • Dick AD, Forrest JV, Liversidge J, Cope AP. The role of tumor necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU). Prog Retin Eye Res. 2004;23(6):617-37.
    • (2004) Prog Retin Eye Res , vol.23 , Issue.6 , pp. 617-637
    • Dick, A.D.1    Forrest, J.V.2    Liversidge, J.3    Cope, A.P.4
  • 8
    • 0031850685 scopus 로고    scopus 로고
    • Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats
    • Okada AA, Sakai J, Usui M, Mizuguchi J. Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats. Ocul Imununol Inflamm. 1998;6(2):111-20.
    • (1998) Ocul Imununol Inflamm , vol.6 , Issue.2 , pp. 111-120
    • Okada, A.A.1    Sakai, J.2    Usui, M.3    Mizuguchi, J.4
  • 9
    • 0025327539 scopus 로고
    • Ocular inflammatory effects of intravitreally injected tumor necrosis factor an endotoxin
    • Fleisher LN, Ferrell JB, McGahan MC. Ocular inflammatory effects of intravitreally injected tumor necrosis factor an endotoxin. Inflammation. 1990;14(3):325-35.
    • (1990) Inflammation , vol.14 , Issue.3 , pp. 325-335
    • Fleisher, L.N.1    Ferrell, J.B.2    McGahan, M.C.3
  • 10
    • 0023684726 scopus 로고
    • Ocular inflammatory effects of intravitreally- injected tumor necrosis factor
    • Rosenbaum JT Howes EL Jr, Rubin RM, Samples JR. Ocular inflammatory effects of intravitreally- injected tumor necrosis factor. Am J Pathol. 1988;133(1):47-53.
    • (1988) Am J Pathol , vol.133 , Issue.1 , pp. 47-53
    • Rosenbaum, J.T.1    Howes Jr., E.L.2    Rubin, R.M.3    Samples, J.R.4
  • 12
    • 0026490785 scopus 로고
    • Ocular and systemic determination of IL-1 beta and tumor necrosis factor in a patient with ocular inflammation
    • Palexas GN, Sussman G, Welsh NH. Ocular and systemic determination of IL-1 beta and tumor necrosis factor in a patient with ocular inflammation. Scand J Immunol. 1192;11:173-5.
    • (1192) Scand J Immunol , vol.11 , pp. 173-175
    • Palexas, G.N.1    Sussman, G.2    Welsh, N.H.3
  • 13
    • 0028361558 scopus 로고
    • Granulomatous reaction to Bruch́s membrane in age-related macular degeneration
    • Dastgheib K, Green WR. Granulomatous reaction to Bruch́s membrane in age - related macular degeneration. Arch Ophthalmol. 1994;112(6):813-8.
    • (1994) Arch Ophthalmol , vol.112 , Issue.6 , pp. 813-818
    • Dastgheib, K.1    Green, W.R.2
  • 14
    • 0027241526 scopus 로고
    • Giant-cell reaction in surgically excised subretinal neovascular membrane
    • Hutchinson AK, Grossniklaus HE, Capone A. Giant-cell reaction in surgically excised subretinal neovascular membrane. Arch Ophthalmol. 1993;111(6):734-5.
    • (1993) Arch Ophthalmol , vol.111 , Issue.6 , pp. 734-735
    • Hutchinson, A.K.1    Grossniklaus, H.E.2    Capone, A.3
  • 15
    • 0025086052 scopus 로고
    • Macrophages related to Bruch́s membrane in age related macular degeneration
    • Killingsworth MC, Sarks JP, Sarks SH. Macrophages related to Bruch́s membrane in age related macular degeneration Eye (Lond). 1990;4(Pt 4):613-21.
    • (1990) Eye (Lond) , vol.4 , Issue.PART 4 , pp. 613-621
    • Killingsworth, M.C.1    Sarks, J.P.2    Sarks, S.H.3
  • 16
    • 0032819686 scopus 로고    scopus 로고
    • The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes
    • Oh H, Takagi H, Takagi C, Suzuma K, Otani A, Ishida K, et al. The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes. Invest Ophthalmol Vis Sci. 1999;40(9):1891-8.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.9 , pp. 1891-1898
    • Oh, H.1    Takagi, H.2    Takagi, C.3    Suzuma, K.4    Otani, A.5    Ishida, K.6
  • 17
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric antitumor necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid placebo en rheumatoid arthritis patients receiving concomitant methotrexate: a randomized phase III trial. ATTRATCT Study Group
    • Maini R, St Clair EW, Breedveld F, Furst D, Kalden J, Weisman M, et al. Infliximab (chimeric antitumor necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid placebo en rheumatoid arthritis patients receiving concomitant methotrexate: a randomized phase III trial. ATTRATCT Study Group. Lancet. 2000;354(9194):1932-9.
    • (2000) Lancet , vol.354 , Issue.9194 , pp. 1932-1939
    • Maini, R.1    St Clair, E.W.2    Breedveld, F.3    Furst, D.4    Kalden, J.5    Weisman, M.6
  • 18
    • 34447532097 scopus 로고    scopus 로고
    • Anti-TNF antibodies for Crohn's disease-in pursuit of the perfect clinical trial
    • Comment in: N Engl J Med. 2007;357(16):1662; author reply 1662. Comment on: N Engl J Med. 2007;357(3):228-38. N Engl J Med. 2007;357(3):239-50.
    • Lewis JD. Anti-TNF antibodies for Crohn's disease-in pursuit of the perfect clinical trial. N Engl J Med. 2007;357(3):296-8.Comment in: N Engl J Med. 2007;357(16):1662; author reply 1662. Comment on: N Engl J Med. 2007;357(3):228-38. N Engl J Med. 2007;357(3):239-50.
    • (2007) N Engl J Med , vol.357 , Issue.3 , pp. 296-298
    • Lewis, J.D.1
  • 20
    • 33748487812 scopus 로고    scopus 로고
    • Treatment of ankylosing spondylitis
    • Clegg DO. Treatment of ankylosing spondylitis. J Rheumatol. Suppl. 2006.78:24-31.
    • (2006) J Rheumatol. Suppl. , vol.78 , pp. 24-31
    • Clegg, D.O.1
  • 21
    • 37849052961 scopus 로고    scopus 로고
    • TN-alpha blockade in human diseases: mechanisms and future directions
    • Wong M, Ziring D, Desai S, Kim S, Lin J, et al. TN-alpha blockade in human diseases: mechanisms and future directions. Clin Imunol. 2008;126(2)121-36.
    • (2008) Clin Imunol , vol.126 , Issue.2 , pp. 121-36
    • Wong, M.1    Ziring, D.2    Desai, S.3    Kim, S.4    Lin, J.5
  • 22
    • 0035963872 scopus 로고    scopus 로고
    • Effect of infliximab on sight-threatening panuveitis in Behcet's disease
    • Comment in: Lancet. 2001;358(9293):1644
    • Sfikakis PP, Theodossiadis PG, Katsiari CG, Kaklamanis P, Markomichelakis NN. Effect of infliximab on sight-threatening panuveitis in Behcet's disease. Lancet. 2001;358(9278):295-6. Comment in: Lancet. 2001;358(9293):1644.
    • (2001) Lancet , vol.358 , Issue.9278 , pp. 295-296
    • Sfikakis, P.P.1    Theodossiadis, P.G.2    Katsiari, C.G.3    Kaklamanis, P.4    Markomichelakis, N.N.5
  • 23
    • 15044342651 scopus 로고    scopus 로고
    • Regression of neovascular age-related macular degeneration following infliximab therapy
    • Marklomichelakis NN, Theodossiadis PG, Sfikakis PP. Regression of neovascular age-related macular degeneration following infliximab therapy. Am J Ophthalmol. 2005;139(3):537-40.
    • (2005) Am J Ophthalmol , vol.139 , Issue.3 , pp. 537-540
    • Marklomichelakis, N.N.1    Theodossiadis, P.G.2    Sfikakis, P.P.3
  • 24
    • 12844263375 scopus 로고    scopus 로고
    • Regression of sight-threatening macular edema in Type 2 diabetes following treatment with the anti-tumor necrosis factor monoclonal antibody infliximab
    • Sfikakis PP, Marklomichelakis N, Theodossiadis GP, Grigoropoulos V, Katsilambros N, Theodossiadis PG. Regression of sight-threatening macular edema in Type 2 diabetes following treatment with the anti-tumor necrosis factor monoclonal antibody infliximab. Diabetes Care. 2005;28(2):445-7.
    • (2005) Diabetes Care , vol.28 , Issue.2 , pp. 445-447
    • Sfikakis, P.P.1    Marklomichelakis, N.2    Theodossiadis, G.P.3    Grigoropoulos, V.4    Katsilambros, N.5    Theodossiadis, P.G.6
  • 28
    • 64349100107 scopus 로고    scopus 로고
    • Intravitreal administration of the anti-tumor necrosis factor agent infliximab for neovascular agerelated macular degeneration
    • Comment in: Am J Ophthalmol. 2009;147(5):761-3
    • Theodossiadis PG, Liarakos VS, Sfikakis PP, Vergados IA, Theodossiadis GP. Intravitreal administration of the anti-tumor necrosis factor agent infliximab for neovascular agerelated macular degeneration. Am J Ophthalmol. 2009;147(5):825-30. Comment in: Am J Ophthalmol. 2009;147(5):761-3.
    • (2009) Am J Ophthalmol , vol.147 , Issue.5 , pp. 825-830
    • Theodossiadis, P.G.1    Liarakos, V.S.2    Sfikakis, P.P.3    Vergados, I.A.4    Theodossiadis, G.P.5
  • 30
    • 77958586098 scopus 로고    scopus 로고
    • Intravitreal infliximab for the reatment of sightthreatening chronic noninfectious uveitis
    • Farvadin M, Afarid M, Mehryar M, Hosseini H. Intravitreal infliximab for the reatment of sightthreatening chronic noninfectious uveitis. Retina. 2010;30(9):1530-5.
    • (2010) Retina , vol.30 , Issue.9 , pp. 1530-1535
    • Farvadin, M.1    Afarid, M.2    Mehryar, M.3    Hosseini, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.