Enhanced antitumor effect of tirapazamine delivered intraperitoneally to VX2 liver tumor-bearing rabbits subjected to transarterial hepatic embolization

CardioVascular and Interventional Radiology

Volumn 34, Issue 6, 2011, Pages 1272-1277

  Sonoda, Akinaga ^a   Nitta, Norihisa ^a   Ohta, Shinich ^a   Nitta Seko, Ayumi ^a   Nagatani, Yukihiro ^a   Takahashi, Masashi ^a   Murata, Kiyoshi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Gelatin microspheres; Hepatic cell carcinoma; Intraperitoneally; Tirapazamine; Transarterial embolization; VX2

Indexed keywords

GELATIN MICROSPHERE; MICROSPHERE; TIRAPAZAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMOEMBOLIZATION; CONTROLLED STUDY; DRUG EFFECT; HYPOXEMIA; LIVER CELL CARCINOMA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RABBIT; TUMOR BLOOD FLOW; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; LIVER NEOPLASMS, EXPERIMENTAL; MAGNETIC RESONANCE IMAGING; MICROSPHERES; RABBITS; TRIAZINES;

EID: 84856764307     PISSN: 01741551     EISSN: 1432086X     Source Type: Journal    
DOI: 10.1007/s00270-011-0156-4     Document Type: Article

References (30)

1. Achenbach T, Seifert JK, Pitton MB, Schunk K, Junginger T (2002) Chemoembolization for primary liver cancer. Eur J Surg Oncol 28(1):37-41 (Pubitemid 41122780)
2. Cha C, DeMatteo RP, Blumgart LH (2002) Surgery and ablative therapy for hepatocellular carcinoma. J Clin Gastroenterol 35(5 Suppl 2):S130-S137 (Pubitemid 35278650)
3. Matsui O, Miyayama S, Sanada J et al (2010) Interventional oncology: new options for interstitial treatments and intravascular approaches: superselective TACE using iodized oil for HCC: rationale, technique and outcome. J Hepatobiliary Pancreat Sci 17(4):407-409
4. Lau W (2003) Future perspectives for hepatocellular carcinoma. HPB (Oxford) 5(4):206-213 (Pubitemid 38008074)
5. Okita K (2006) Clinical aspects of hepatocellular carcinoma in Japan. Intern Med 45(5):229-233
6. Lau WY, Lai EC (2008) Hepatocellular carcinoma: current management and recent advances. Hepatobiliary Pancreat Dis Int 7(3):237-257 (Pubitemid 351895383)
7. Huang YH, Chen CH, Chang TT et al (2005) The role of transcatheter arterial embolization for patients with unresectable hepatocellular carcinoma: a nationwide, multicentre study evaluated by cancer stage. Aliment Pharmacol Ther 21(6):687-694
8. Llovet JM, Bruix J (2003) Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology 37(2):429-442 (Pubitemid 36152543)
9. Miyayama S, Matsui O, Yamashiro M et al (2007) Visualization of hepatic lymphatic vessels during transcatheter arterial chemoembolization for hepatocellular carcinoma. J Vasc Interv Radiol 18(9):1111-1117 (Pubitemid 47332219)
10. Brown JM (1999) The hypoxic cell: a target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res 59(23):5863-5870 (Pubitemid 30004940)
11. Peters KB, Brown JM (2002) Tirapazamine: a hypoxia-activated topoisomerase II poison. Cancer Res 62(18):5248-5253 (Pubitemid 35024598)
12. Rauth AM, Melo T, Misra V (1998) Bioreductive therapies: an overview of drugs and their mechanisms of action. Int J Radiat Oncol Biol Phys 42(4):755-762 (Pubitemid 28559412)
13. Shi X, Mandel SM, Platz MS (2007) On the mechanism of reaction of radicals with tirapazamine. J Am Chem Soc 129(15):4542-4550 (Pubitemid 46648753)
14. Cohen EE, Rosine D, Haraf DJ et al (2007) Phase I trial of tirapazamine, cisplatin, and concurrent accelerated boost reirradiation in patients with recurrent head and neck cancer. Int J Radiat Oncol Biol Phys 67(3):678-684 (Pubitemid 46215895)
15. Covens A, Blessing J, Bender D, Mannel R, Morgan M (2006) A phase II evaluation of tirapazamine plus cisplatin in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group study. Gynecol Oncol 100(3):586-590 (Pubitemid 43250628)
16. Maluf FC, Leiser AL, Aghajanian C et al (2006) Phase II study of tirapazamine plus cisplatin in patients with advanced or recurrent cervical cancer. Int J Gynecol Cancer 16(3):1165-1171 (Pubitemid 43886741)
17. Haaga JR, Exner AA, Wang Y, Stowe NT, Tarcha PJ (2005) Combined tumor therapy by using radiofrequency ablation and 5-FU-laden polymer implants: evaluation in rats and rabbits. Radiology 237(3):911-918 (Pubitemid 41636381)
18. Miyayama S, Mitsui T, Zen Y et al (2009) Histopathological findings after ultraselective transcatheter arterial chemoembolization for hepatocellular carcinoma. Hepatol Res 39(4):374-381
19. Rischin D, Narayan K, Oza AM et al (2010) Phase 1 study of tirapazamine in combination with radiation and weekly cisplatin in patients with locally advanced cervical cancer. Int J Gynecol Cancer 20(5):827-833
20. Ohta S, Nitta N, Takahashi M, Murata K, Tabata Y (2007) Degradable gelatin microspheres as an embolic agent: an experimental study in a rabbit renal model. Korean J Radiol 8(5):418-428
21. Nitta-Seko A, Nitta N, Sonoda A et al. (2010) Anti-tumour effects of transcatheter arterial embolisation administered in combination with thalidomide in a rabbit VX2 liver tumour model. Br J Radiol 83:428-32
22. Sonoda A, Nitta N, Ohta S et al (2010) Controlled release and antitumor effect of Pluronic F127 mixed with cisplatin in a rabbit model. Cardiovasc Intervent Radiol 33(1):135-142
23. Wright KC, Yang P, Van Pelt CS, Hicks ME, Collin P, Newman RA (2005) Evaluation of targeted arterial delivery of the branched chain fatty acid 12-methyltetradecanoic acid as a novel therapy for solid tumors. J Exp Ther Oncol 5(1):55-68 (Pubitemid 41076991)
24. Dorie MJ, Brown JM (1993) Tumor-specific, schedule-dependent interaction between tirapazamine (SR 4233) and cisplatin. Cancer Res 53(19):4633-4636 (Pubitemid 23304391)
25. Bains LJ, Baker JH, Kyle AH, Minchinton AI, Reinsberg SA (2009) Detecting vascular-targeting effects of the hypoxic cytotoxin tirapazamine in tumor xenografts using magnetic resonance imaging. Int J Radiat Oncol Biol Phys 74(3):957-965
26. Gu T, Li CX, Feng Y, Wang Q, Li CH, Li CF (2007) Transarterial gene therapy for hepatocellular carcinoma in a rabbit model. World J Gastroenterol 13(14):2113-2117 (Pubitemid 46795852)
27. Yumoto Y, Jinno K, Inatsuki S et al (1992) Treatment of hepatocellular carcinoma by transcatheter hepatic arterial injection of radioactive iodized oil solution. Cancer Chemother Pharmacol 31(Suppl):S128-S136
28. Ohta S, Nitta N, Sonoda A et al (2009) Cisplatin-conjugated degradable gelatin microspheres: fundamental study in vitro. Br J Radiol 82(977):380-385
29. Wouters BG, Wang LH, Brown JM (1999) Tirapazamine: a new drug producing tumor specific enhancement of platinum-based chemotherapy in non-small-cell lung cancer. Ann Oncol 10(Suppl 5):S29-S33 (Pubitemid 29522779)
30. Ohta S, Nitta N, Sonoda A et al (2009) Prolonged local persistence of cisplatin-loaded gelatin microspheres and their chemoembolic anti-cancer effect in rabbits. Eur J Radiol 72(3):534-540