Targeting IL-6 promoter polymorphism -174G/C should be dependent on ethnicity

Clinical Rheumatology

Volumn 31, Issue 1, 2012, Pages 191-192

  Xu, Wang Dong ^a   Zhang, Yu Jing ^a   Pan, Hai Feng ^a   Ye, Dong Qing ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; INTERLEUKIN 6; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

AFRICAN AMERICAN; ASIAN; CYTOKINE PRODUCTION; ENVIRONMENTAL FACTOR; ETHNICITY; GENE INTERACTION; GENE TARGETING; GENE THERAPY; GENETIC PREDISPOSITION; GENOTYPE ENVIRONMENT INTERACTION; HEREDITY; HISPANIC; LETTER; LUPUS ERYTHEMATOSUS NEPHRITIS; PRIORITY JOURNAL; PROMOTER REGION; RACE DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT RESPONSE;

DRUG DELIVERY SYSTEMS; ETHNIC GROUPS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-6; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 84856761672     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-011-1867-2     Document Type: Letter

References (10)

1. M Linker-Israeli DJ Wallace J Prehn D Michael M Honda KD Taylor M Paul-Labrador N Fischel-Ghodsian PA Fraser JR Klinenberg 1999 Association of IL-6 gene alleles with systemic lupus erythematosus (SLE) and with elevated IL-6 expression Genes Immun 1 1 45 52 11197305 10.1038/sj.gene.6363631 1:CAS:528:DC%2BD3cXktlyiu78%3D (Pubitemid 129622780)
2. A Hrycek U Siekiera P Cieélik W Szkróbka 2005 HLA-DRB1 and -DQB1 alleles and gene polymorphisms of selected cytokines in systemic lupus erythematosus Rheumatol Int 26 1 1 6 15449022 10.1007/s00296-004-0503-8 1:CAS:528:DC%2BD2MXhtFCrtL7J (Pubitemid 41531506)
3. P Guarnizo-Zuccardi Y Lopez M Giraldo N Garcia L Rodriguez L Ramirez O Uribe L Garcia G Vasquez 2007 Cytokine gene polymorphisms in Colombian patients with systemic lupus erythematosus Tissue Antigens 70 5 376 382 17711410 10.1111/j.1399-0039.2007.00917.x 1:CAS:528:DC%2BD2sXhtlaktr%2FO (Pubitemid 47537398)
4. KH Chua BP Kee SY Tan LH Lian 2009 Interleukin-6 promoter polymorphisms (-174G/C) in Malaysian patients with systemic lupus erythematosus Braz J Med Biol Res 42 2 551 555 19448905 10.1590/S0100-879X2009000600012 1:CAS:528:DC%2BD1MXosVynt7Y%3D
5. H Schotte B Schlüter S Rust G Assmann W Domschke M Gaubitz 2001 Interleukin-6 promoter polymorphisms (-174G/C) in Caucasian German with systemic lupus erythematosus Rheumatology 40 4 393 400 11312376 10.1093/rheumatology/40. 4.393 1:CAS:528:DC%2BD3MXjvVaktLg%3D
6. EM Godarzi EK Sarvestani E Aflaki Z Amirghofran 2011 Interleukin-6 gene polymorphism in Iranian patients with systemic lupus erythematosus Clin Rheumatol 30 2 179 184 20383729 10.1007/s10067-010-1452-0
7. MJ Santos D Santos S Capela JC da Silva JE Fonseca 2011 Interleukin-6 promoter polymorphism -174G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients Clin Rheumatol 30 3 409 413 21153673 10.1007/s10067-010-1640-y
8. S Bernatsky C Peschken PR Fortin CA Pineau MB Urowitz DD Gladman JE Pope M Hudson M Zummer CD Smith HO Arbillaga AE Clarke 2011 Medication use in systemic lupus erythematosus J Rheumatol 38 2 271 274 21078722 10.3899/jrheum.100414
9. D Isenberg GB Appel G Contreras MA Dooley EM Ginzler D Jayne J Sánchez-Guerrero D Wofsy X Yu N Solomons 2010 Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study Rheumatology 49 1 128 140 19933596 10.1093/rheumatology/kep346
10. HS Lee SC Bae 2010 What can we learn from genetic studies of systemic lupus erythematosus? Implications of genetic heterogeneity among populations in SLE Lupus 19 12 1452 1459 20947557 10.1177/0961203310370350 1:CAS:528: DC%2BC3cXhsFCjsr7N