Acute ethanol exposure affects spermatogonial stem cell homeostasis in pre-pubertal mice

Reproductive Toxicology

Volumn 33, Issue 1, 2012, Pages 76-84

  Caires, Kyle C ^a   Shima, Christina M ^a   De Avila, Jeanene ^a   McLean, Derek J ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Ethanol; Gamete biology; Germ cells; Male infertility; Spermatogenesis; Spermatogonial stem cells; Stem cell transplantation; Stem cells

Indexed keywords

ALCOHOL; BUSULFAN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; VASCULOTROPIN;

ALCOHOL INTOXICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GERM CELL; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPERMATOGONIUM; STEM CELL TRANSPLANTATION;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HOMEOSTASIS; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MICE, INBRED C57BL; RISK ASSESSMENT; RNA, MESSENGER; SEXUAL DEVELOPMENT; SPERMATOGONIA; STEM CELL NICHE; STEM CELL TRANSPLANTATION; STEM CELLS; TESTIS; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTORS;

MUS;

EID: 84856741301     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.12.002     Document Type: Article

References (31)

1. McLean D.J. Spermatogonial stem cell transplantation and testicular function. Cell Tissue Res. 2005, 322:21-31.
2. Orwig K.E., Shinohara T., Avarbock M.R., Brinster R.L. Functional analysis of stem cells in the adult rat testis. Biol Reprod 2002, 66:944-949.
3. McLean D.J., Friel P.J., Johnston D.S., Griswold M.D. Characterization of spermatogonial stem cell maturation and differentiation in neonatal mice. Biol Reprod 2003, 69:2085-2091.
4. Caires K., Broady J., McLean D. Maintaining the male germline: regulation of spermatogonial stem cells. J Endocrinol 2010, 205:133-145.
5. Kubota H., Avarbock M.R., Brinster R.L. Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci USA 2004, 101:16489-16494.
6. Oatley J.M., Avarbock M.R., Brinster R.L. Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase signaling. J Biol Chem 2007, 282:25842-25851.
7. Wu X., Oatley J.M., Oatley M.J., Kaucher A.V., Avarbock M.R., Brinster R.L. The POU domain transcription factor POU3F1 is an important intrinsic regulator of GDNF-induced survival and self-renewal of mouse spermatogonial stem cells. Biol Reprod 2010, 82:1103-1111.
8. Caires K.C., de Avila J., McLean D.J. Vascular endothelial growth factor regulates germ cell survival during establishment of spermatogenesis in the bovine testis. Reproduction 2009, 138:667-677.
9. McAlhany R.E., Miranda R.C., Finnell R.H., West J.R. Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res 1999, 23:1691-1697.
10. Tsuji R., Fattori V., Abe S., Costa L.G., Kobayashi K. Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain. Neurotoxicol Teratol 2008, 30:228-236.
11. Wentzel P., Eriksson U.J. Altered gene expression in neural crest cells exposed to ethanol in vitro. Brain Res. 2009, 1305(Suppl):S50-S60.
12. Fiore M., Mancinelli R., Aloe L., Laviola G., Sornelli F., Vitali M., et al. Hepatocyte growth factor, vascular endothelial growth factor, glial cell-derived neurotrophic factor and nerve growth factor are differentially affected by early chronic ethanol or red wine intake. Toxicol Lett 2009, 188:208-213.
13. Radek K.A., Matthies A.M., Burns A.L., Heinrich S.A., Kovacs E.J., Dipietro L.A. Acute ethanol exposure impairs angiogenesis and the proliferative phase of wound healing. Am J Physiol Heart Circ Physiol 2005, 289:H1084-H1090.
14. Radek K.A., Kovacs E.J., Gallo R.L., DiPietro L.A. Acute ethanol exposure disrupts VEGF receptor cell signaling in endothelial cells. Am J Physiol Heart Circ Physiol 2008, 295:H174-H184.
15. Ceccanti M., Mancinelli R., Tirassa P., Laviola G., Rossi S., Romeo M., et al. Early exposure to ethanol or red wine and long-lasting effects in aged mice. A study on nerve growth factor, brain-derived neurotrophic factor, hepatocyte growth factor, and vascular endothelial growth factor. Neurobiol Aging 2010.
16. Farghali H., Williams D.S., Caraceni P., Borle A.B., Gasbarrini A., Gavaler J., et al. Effect of ethanol on energy status and intracellular calcium of Sertoli cells: a study using immobilized perfused cells. Endocrinology 1993, 133:2749-2755.
17. Zhu Q., Van Thiel D.H., Gavaler J.S. Effects of ethanol on rat Sertoli cell function: studies in vitro and in vivo. Alcohol Clin Exp Res 1997, 21:1409-1417.
18. Zhu Q., Meisinger J., Emanuele N.V., Emanuele M.A., LaPaglia N., Van Thiel D.H. Ethanol exposure enhances apoptosis within the testes. Alcohol Clin Exp Res 2000, 24:1550-1556.
19. Van Thiel D.H., Gavaler J.S., Lester R., Goodman M.D. Alcohol-induced testicular atrophy. An experimental model for hypogonadism occurring in chronic alcoholic men. Gastroenterology 1975, 69:326-332.
20. Li H., Kim K.H. Effects of ethanol on embryonic and neonatal rat testes in organ cultures. J Androl 2003, 24:653-660.
21. Olney J.W., Tenkova T., Dikranian K., Qin Y.Q., Labruyere J., Ikonomidou C. Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain. Brain Res Dev Brain Res 2002, 133:115-126.
22. Young C., Klocke B.J., Tenkova T., Choi J., Labruyere J., Qin Y.Q., et al. Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Cell Death Differ 2003, 10:1148-1155.
23. Saito M., Mao R.F., Wang R., Vadasz C. Effects of gangliosides on ethanol-induced neurodegeneration in the developing mouse brain. Alcohol Clin Exp Res 2007, 31:665-674.
24. Buaas F.W., Kirsh A.L., Sharma M., McLean D.J., Morris J.L., Griswold M.D., et al. Plzf is required in adult male germ cells for stem cell self-renewal. Nat Genet 2004, 36:647-652.
25. Doyle T.J., Braun K.W., McLean D.J., Wright R.W., Griswold M.D., Kim K.H. Potential functions of retinoic acid receptor A in Sertoli cells and germ cells during spermatogenesis. Ann NY Acad Sci 2007, 1120:114-130.
26. Caires K.C., Schmidt J.A., Oliver A.P., de Avila J., McLean D.J. Endocrine regulation of the establishment of spermatogenesis in pigs. Reprod Domest Anim 2008, 43(Suppl. 2):280-287.
27. Muller P.Y., Janovjak H., Miserez A.R., Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002, 32. p. 1372-4, 6, 8, 9.
28. Simon P. Q-Gene: processing quantitative real-time RT-PCR data. Bioinformatics 2003, 19:1439-1440.
29. Meng X., Lindahl M., Hyvonen M.E., Parvinen M., de Rooij D.G., Hess M.W., et al. Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science 2000, 287:1489-1493.
30. Oatley J.M., Avarbock M.R., Telaranta A.I., Fearon D.T., Brinster R.L. Identifying genes important for spermatogonial stem cell self-renewal and survival. Proc Natl Acad Sci USA 2006, 103:9524-9529.
31. Jijiwa M., Kawai K., Fukihara J., Nakamura A., Hasegawa M., Suzuki C., et al. GDNF-mediated signaling via RET tyrosine 1062 is essential for maintenance of spermatogonial stem cells. Genes Cells 2008, 13:365-374.