The -409 C/T genotype of PRSS1 protects against pancreatic cancer in the han chinese population

Digestive Diseases and Sciences

Volumn 57, Issue 2, 2012, Pages 573-579

  Liu, Qicai ^a   Lin, Xinhua ^a   Liu, Jingfeng ^a   Liu, Ailin ^a   Gao, Feng ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Haplotype; Pancreatic cancer; Polymorphism; PRSS1 gene; Risk

Indexed keywords

GENOMIC DNA; PRSS1 PROTEIN; TRYPSIN; TRYPSINOGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; CANCER RESISTANCE; CANCER RISK; CHINESE; CONTROLLED STUDY; FEMALE; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; TRYPSIN;

EID: 84856728394     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-011-1893-6     Document Type: Article

References (39)

1. AC Tersmette GM Petersen GJ Offerhaus, et al. 2001 Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer Clin Cancer Res 7 738 744 11297271 1:STN:280:DC%2BD3Mrks1Kktg%3D%3D (Pubitemid 32708001)
2. MA Eberle R Pfutzer KL Pogue-Geile, et al. 2002 A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34 Am J Hum Genet 70 1044 1048 11870593 10.1086/339692 1:CAS:528:DC%2BD38XivFClu7c%3D (Pubitemid 34259323)
3. MS van der Heijden CJ Yeo RH Hruban SE Kern 2003 Fanconianemia gene mutations in young-onset pancreatic cancer Cancer Res 63 2585 2588 12750283 (Pubitemid 36605199)
4. B Cox Q Waisfisz C Die-Smulders, et al. 2002 Biallelic inactivation of BRCA2 in fanconianemia Science 297 606 609 12065746 10.1126/science.1072188 (Pubitemid 34839632)
5. KM Murphy KA Brune C Griffin, et al. 2002 Evaluation of candidate genes MAP2K4, MADH4, ACVR1B and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17% Cancer Res 62 3789 3793 12097290 1:CAS:528: DC%2BD38XltF2jur0%3D (Pubitemid 34728862)
6. A Jemal R Siegel E Ward, et al. 2007 Cancer statistics 2007 CA Cancer J Clin 57 43 66 17237035 10.3322/canjclin.57.1.43
7. G Zogopoulos H Rothenmund A Eppel, et al. 2007 The P239S palladin variant does not account for a significant fraction of hereditary or early onset pancreas cancer Hum Genet 121 635 637 17415588 10.1007/s00439-007-0361-z (Pubitemid 46706075)
8. SJ Rulyak AB Lowenfels P Maisonneuve TA Brentnall 2003 Risk factors for the development of pancreatic cancer in familial pancreatic cancer kindred's Gastroenterology 124 1292 1299 12730869 10.1016/S0016-5085(03)00272-5 (Pubitemid 36531804)
9. O Ikeda H Egami T Ishiko S Ishikawa, et al. 2006 Signal of proteinase-activated receptor-2 contributes to highly malignant potential of human pancreatic cancer by up-regulation of interleukin-8 release Int J Oncol 28 939 946 16525644 1:CAS:528:DC%2BD28XjtlCqtLY%3D
10. V Rebours MC Boutron-Ruault M Schnee, et al. 2008 Risk of pancreatic adenocarcinoma in patients with hereditary pancreatitis: a national exhaustive series Am J Gastroenterol 103 111 119 18184119
11. JG Hengstler A Bauer HK Wolf, et al. 2000 Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer Anticancer Res 20 2967 2974 11062709 1:CAS:528:DC%2BD3cXnvVequ7Y%3D
12. B Farrow BM Evers 2002 Inflammation and the development of pancreatic cancer Surg Oncol 10 153 169 12020670 10.1016/S0960-7404(02)00015-4 (Pubitemid 34520439)
13. JM Chen C Férec 2009 Chronic pancreatitis: genetics and pathogenesis Annu Rev Genomics Hum Genet 10 63 87 19453252 10.1146/annurev- genom-082908-150009 1:CAS:528:DC%2BD1MXht12qsrrF
14. QC Liu F Gao QS Ou, et al. 2008 Novel mutation and polymorphism of PRSS1 gene in the Chinese patients with hereditary pancreatitis and chronic pancreatitis Chin Med J 121 108 111 18272034 10.1016/S1001-9294(09)60021-3 1:CAS:528:DC%2BD1cXmsFGqsLo%3D (Pubitemid 352000973)
15. A Jemal R Siegel E Ward, et al. 2008 Cancer statistics 2008 CA Cancer J Clin 58 71 96 18287387 10.3322/CA.2007.0010 (Pubitemid 351521864)
16. R Szmola M Sahin-Tóth 2010 Uncertainties in the classification of human cationic trypsinogen (PRSS1) variants as hereditary pancreatitis- associated mutations J Med Genet 47 348 350 20452997 10.1136/jmg.2009.072751 1:CAS:528:DC%2BC3cXotVWltL4%3D
17. V Rebours P Lévy JF Mosnier, et al. 2010 Pathology analysis reveals that dysplastic pancreatic ductal lesions are frequent in patients with hereditary pancreatitis Clin Gastroenterol Hepatol 8 206 212 19765677 10.1016/j.cgh.2009.09.009
18. JM Chen C Le Mar'echal D Lucas, et al. 2003 Loss-of-function mutations in the cationic trypsinogen gene (PRSS1) may act as a protective factor against pancreatitis Mol Genet Metab 79 67 70 12765848 10.1016/S1096-7192(03)00050-7 1:CAS:528:DC%2BD3sXjvFeqs7s%3D (Pubitemid 36579443)
19. H Witt M Sahin-Toth O Landt, et al. 2006 A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis Nat Genet 38 668 673 16699518 10.1038/ng1797 1:CAS:528:DC%2BD28XltVOhtbc%3D (Pubitemid 43927309)
20. L Jiao ML Bondy MM Hassan, et al. 2007 Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer Cancer 109 840 848 17265526 10.1002/cncr.22468 1:CAS:528:DC%2BD2sXjsVKns7g%3D (Pubitemid 46333525)
21. R Ducroc C Bontemps K Marazova, et al. 2002 Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop Life Sci 270 1359 1367 10.1016/S0024-3205(01)01519-3 (Pubitemid 34159093)
22. R Shimamoto T Sawada Y Uchima, et al. 2004 A role for protease-activated receptor-2 in pancreatic cancer cell proliferation Int J Oncol 24 1401 1406 15138580 1:CAS:528:DC%2BD2cXkvFaisrs%3D
23. AB Lowenfels P Maisonneuve DC Whitcomb, et al. 2001 Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis JAMA 286 169 170 11448279 10.1001/jama.286.2.169 1:STN:280: DC%2BD3MvgslCnuw%3D%3D (Pubitemid 32640846)
24. SJ Rulyak AB Lowenfels P Maisonneuve TA Brentnall 2003 Risk factors for the development of pancreatic cancer in familial pancreatic cancer kindred's Gastroenterology 124 1292 1299 12730869 10.1016/S0016-5085(03)00272-5 (Pubitemid 36531804)
25. R Huxley A Ansary-Moghaddam DG Berrington, et al. 2005 Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies Br J Cancer 92 2076 2083 15886696 10.1038/sj.bjc.6602619 1:STN:280:DC%2BD2M3ot1Kjug%3D%3D (Pubitemid 40897433)
26. ST Chari CL Leibson KG Rabe, et al. 2005 Probability of pancreatic cancer following diabetes: a population-based study Gastroenterology 129 504 511 16083707 (Pubitemid 41096638)
27. QC Liu ZH Zhuang K Zeng, et al. 2009 Prevalence of pancreatic diabetes in patients carrying mutations or polymorphisms of the PRSS1 gene in the Han population Diabetes Technol Ther 11 799 804 20001681 10.1089/dia.2009.0051 1:CAS:528:DC%2BC3cXjslWmtg%3D%3D
28. N Howes MM Lerch W Greenhalf, et al. 2004 Clinical and genetic characteristics of hereditary pancreatitis in Europe Clin Gastroenterol Hepatol 2 252 261 15017610 10.1016/S1542-3565(04)00013-8 1:CAS:528:DC%2BD2cXjtVCktb0%3D (Pubitemid 38293313)
29. AB Lowenfels P Maisonneuve DC Whitcomb, et al. 2001 Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis J Am Med Assoc 286 169 170 10.1001/jama.286.2.169 1:STN:280:DC%2BD3MvgslCnuw%3D%3D (Pubitemid 32640846)
30. V Dale G Paula C Eithne N John 2004 Genetics and prevention of pancreatic cancer Cancer Control 11 6 14
31. DC Whitcomb 2010 Genetic aspects of pancreatitis Annu Rev Med 61 413 424 20059346 10.1146/annurev.med.041608.121416 1:CAS:528:DC%2BC3cXisFyltr4%3D
32. V Rebours MC Boutron-Ruault M Schnee, et al. 2008 Risk of pancreatic adenocarcinoma in patients with hereditary pancreatitis: a national exhaustive series Am J Gastroenterol 103 111 119 18184119
33. C Berndt K Haubold F Wenger, et al. 1998 k-ras mutations in stools and tissue samples from patients with malignant and nonmalignant pancreatic diseases Clin Chem 44 2103 2107 9761241 1:CAS:528:DyaK1cXmtlSntr4%3D (Pubitemid 28447056)
34. Z Tang G Geng Q Huang, et al. 2010 Prognostic significance of tissue factor pathway inhibitor-2 in pancreatic carcinoma and its effect on tumor invasion and metastasis Med Oncol 27 867 875 19763915 10.1007/s12032-009-9298-5 1:CAS:528:DC%2BC3cXhtVCnurfO
35. R Caruso F Pallone D Fina, et al. 2006 Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor trans-activation and proliferation Am J Pathol 169 268 278 16816379 10.2353/ajpath.2006.050841 1:CAS:528:DC%2BD28XnslSntbw%3D
36. VS Ossovskaya NW Bunnett 2004 Protease-activated receptors: contribution to physiology and disease Physiol Rev 84 579 621 15044683 10.1152/physrev.00028. 2003 1:CAS:528:DC%2BD2cXjtlCktLY%3D (Pubitemid 38365493)
37. CJ Grocock V Rebours MN Delhaye, et al. 2010 The variable phenotype of the p. A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families Gut 59 357 363 19951905 10.1136/gut.2009.186817 1:CAS:528:DC%2BC3cXkvVOkur0%3D
38. X Dong L Jiao Y Li, et al. 2009 Significant Associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer J Clin Oncol 27 1592 1599 19237629 10.1200/JCO.2008.20.1111 1:CAS:528: DC%2BD1MXltVOhtrs%3D
39. BM Pickering AE Willis 2005 The implications of structured 5′ untranslated regions on translation and disease Semin Cell Dev Biol 16 39 47 15659338 10.1016/j.semcdb.2004.11.006 1:CAS:528:DC%2BD2MXkvFOhtw%3D%3D (Pubitemid 40126875)