Characteristics of patients with primary non-adherence to medications for hypertension, diabetes, and lipid disorders

Journal of General Internal Medicine

Volumn 27, Issue 1, 2012, Pages 57-64

  Raebel, Marsha A ^a,b   Ellis, Jennifer L ^a   Carroll, Nikki M ^a   Bayliss, Elizabeth A ^a,c   McGinnis, Brandy ^b,d   Schroeder, Emily B ^a,c   Shetterly, Susan ^a   Xu, Stan ^a   Steiner, John F ^a,c  

^a KAISER PERMANENTE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d NONE   (United States)

Author keywords

antidiabetic adherence; antihyperlipidemic adherence; antihypertensive adherence; medication adherence; primary non adherence

Indexed keywords

ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT;

ADULT; ANTIHYPERTENSIVE THERAPY; ARTICLE; CAUCASIAN; DIABETES MELLITUS; ETHNICITY; FEMALE; HEALTH INSURANCE; HISPANIC; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PATIENT COMPLIANCE; PRESCRIPTION; RETROSPECTIVE STUDY; TREATMENT REFUSAL;

AGED; ANTIHYPERTENSIVE AGENTS; COHORT STUDIES; DIABETES MELLITUS; FEMALE; HUMANS; HYPERLIPIDEMIAS; HYPERTENSION; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 84856720108     PISSN: 08848734     EISSN: 15251497     Source Type: Journal    
DOI: 10.1007/s11606-011-1829-z     Document Type: Article

References (35)

1. R Balkrishnan 2005 The importance of medication adherence in improving chronic-disease related outcomes: what we know and what we need to further know Med Care 43 517 520 15908845 10.1097/01.mlr.0000166617.68751.5f (Pubitemid 40847287)
2. L Osterberg T Blaschke 2005 Adherence to medication N Engl J Med 353 487 497 16079372 10.1056/NEJMra050100 1:CAS:528:DC%2BD2MXntVCisL0%3D (Pubitemid 41127293)
3. EA Walker M Molitch MK Kramer, et al. 2006 Adherence to preventive medications: predictors and outcomes in the Diabetes Prevention Program Diabetes Care 29 1997 2002 16936143 10.2337/dc06-0454 (Pubitemid 44871177)
4. JR Wu DK Moser MJ DeJong, et al. 2009 Defining an evidence-based cutpoint for medication adherence in heart failure Am Heart J 157 285 291 19185635 10.1016/j.ahj.2008.10.001
5. MC Sokol KA McGuigan RR Verbrugge RS Epstein 2005 Impact of medication adherence on hospitalization risk and healthcare cost Med Care 43 521 530 15908846 10.1097/01.mlr.0000163641.86870.af (Pubitemid 40847288)
6. PM Ho DJ Magid SM Shetterly, et al. 2008 Importance of therapy intensification and medication nonadherence for blood pressure control in patients with coronary disease Arch Intern Med 168 271 276 18268167 10.1001/archinternmed.2007.72 (Pubitemid 351281672)
7. BD McGinnis KL Olson TMA Delate RS Stolcpart 2009 Statin adherence and mortality in patients enrolled in a secondary prevention program Am J Manag Care 15 689 695 19845421
8. PM Ho JS Rumsfeld FA Masoudi, et al. 2006 Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus Arch Intern Med 166 1836 1841 17000939 10.1001/archinte.166.17.1836 (Pubitemid 44455165)
9. SE Andrade KH Kahler F Frech KA Chan 2006 Methods for evaluation of medication adherence and persistence using automated databases Pharmacoepidemiol Drug Saf 15 565 574 16514590 10.1002/pds.1230 (Pubitemid 44336271)
10. NR Shah AG Hirsch C Zacker S Taylor GC Wood WF Stewart 2009 Factors associated with first-fill adherence rates for diabetic medications: a cohort study J Gen Intern Med 24 233 237 19093157 10.1007/s11606-008-0870-z
11. PHG Beardon MM McGilchrist AD McKendrick DG McDevitt TM MacDonald 1993 Primary non-compliance with prescribed medication Br Med J 307 846 868 10.1136/bmj.307.6908.846 1:STN:280:DyaK2c%2FgsVeltA%3D%3D
12. AJ Karter MM Parker HH Moffet AM Ahmed JA Schmittdiel JV Selby 2009 New prescription medication gaps: a comprehensive measure of adherence to new prescriptions Health Serv Res 44 5p1 1640 1661 19500161 10.1111/j.1475-6773. 2009.00989.x
13. NR Shah AG Hirsch C Zacker, et al. 2009 Predictors of first-fill adherence for patients with hypertension Am J Hypertens 22 392 396 19180061 10.1038/ajh.2008.367
14. MA Fischer MR Stedman J Lii, et al. 2010 Primary medication non-adherence: analysis of 195,930 electronic prescriptions J Gen Intern Med 25 284 290 20131023 10.1007/s11606-010-1253-9
15. Carroll NM, Ellis JL, Luckett C, Raebel MA. Feasibility of determining medication adherence from electronic health record medications orders. J Am Med Inform Assoc 2011, doi: 10.1136/amiajnl-2011-000151
16. LM Hess MA Raebel DA Conner DC Malone 2006 Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures Ann Pharmacother 40 1280 1288 16868217 10.1345/aph.1H018 (Pubitemid 44204957)
17. H Quan V Sundararajan P Halfon, et al. 2005 Coding algorithms for defining comorbidities in ICD-9-Cm and ICD-10 administrative data Med Care 43 1130 1139 16224307 10.1097/01.mlr.0000182534.19832.83 (Pubitemid 41587600)
18. AJ Karter MM Parker AS Adams, et al. 2010 Primary non-adherence to prescribed medications J Gen Intern Med 25 763 20440573 10.1007/s11606-010-1381- 2
19. AH Traylor JA Schmittdiel CS Uratsu CM Mangione U Subramanian 2010 Adherence to cardiovascular disease medications: does patient-provider race/ethnicity and language concordance matter? J Gen Intern Med 25 1172 1177 20571929 10.1007/s11606-010-1424-8
20. HA Batal MJ Krantz RA Dale PS Mehler JF Steiner 2007 Impact of prescription size on statin adherence and cholesterol levels BMG Health Serv Res 7 175 10.1186/1472-6963-7-175
21. S Kripalani ME Gatti TA Jacobson 2010 Association of age, health literacy, and medication management strategies with cardiovascular medication adherence Patient Educ Couns 178 81 177 181 10.1016/j.pec.2010.04.030
22. DM Mann M Woodward P Munter L Falzon I Kronish 2010 Predictors of nonadherence to statins: a systematic review and meta-analysis Ann Pharmacother 44 1410 1421 20702755 10.1345/aph.1P150
23. AM Colombi K Yu-Isenberg J Priest 2008 The effects of health plan copayments on adherence to oral diabetes medication and health resource utilization J Occup Environ Med 50 535 541 18469622 10.1097/JOM.0b013e31816ed011 (Pubitemid 351677636)
24. BA Briesacher SE Andrade H Fouayzi KA Chan 2008 Comparison of drug adherence rates among patients with seven different medical conditions Pharmacother 28 437 443 10.1592/phco.28.4.437 (Pubitemid 351466455)
25. DM Mann JP Allengrante S Natarajan, et al. 2007 Predictors of adherence to statins for primary prevention Cardiovasc Drugs Ther 21 311 316 17665294 10.1007/s10557-007-6040-4 (Pubitemid 47387472)
26. HB Haskard Zolnierek MR DiMatteo 2009 Physician communication and patient adherence to treatment: a meta-analysis Med Care 47 8 826 834 10.1097/MLR.0b013e31819a5acc
27. ID Kalsekar SS Madhaven MM Amonkar, et al. 2006 Depression in patients with type 2 diabetes: impact on adherence to oral hypoglycemic agents Ann Pharmacother 40 605 611 16551768 10.1345/aph.1G606
28. JF Mateo VF Gil-Guillen E Mateo D Orozco JA Carbayo J Merino 2006 Multifactorial approach and adherence to prescribed oral medications in patients with type 2 diabetes Int J Clin Pract 60 422 428 16620354 10.1111/j.1368-5031. 2006.00799.x 1:STN:280:DC%2BD283hsFWmug%3D%3D
29. CW Tseng EF Tierney RB Gerzoff, et al. 2008 Race/ethnicity and economic differences in cost-related medication underuse among insured adults with diabetes Diabetes Care 31 261 266 18000177 10.2337/dc07-1341 (Pubitemid 351213332)
30. DC Chan WH Shrank D Cutler, et al. 2010 Patient, physician, and payment predictors of statin adherence Med Care 48 196 202 19890219 10.1097/MLR. 0b013e3181c132ad
31. V Fung F Sinclair H Wang D Dailey J Hsu R Shaber 2010 Patients' perspectives on nonadherence to statin therapy: a focus-group study Permanente J 14 4 10
32. KL Olson J Rasmussen BG Sandhoff JA Merenich for the Clinical Pharmacy Cardiac Risk Service (CPCRS) Study Group 2005 Lipid management in patients with coronary artery disease by a clinical pharmacy service in a group model health maintenance organization Arch Intern Med 165 49 54 15642874 10.1001/archinte. 165.1.49 (Pubitemid 40096081)
33. JA Merenich KL Olson T Delate, et al. 2007 Mortality reduction benefits of a comprehensive cardiac care program for patients with occlusive coronary artery disease Pharmacother 27 1370 1378 10.1592/phco.27.10.1370 (Pubitemid 47530443)
34. JF Steiner PM Ho BL Beaty, et al. 2010 Sociodemographic and clinical characteristics are not clinically useful predictors of refill adherence in patients with hypertension Circulation: Cardiovasc Qual Outcomes 2 452 457
35. JS Steiner 2010 Can we identify clinical predictors of medication adherence ... and should we? Med Care 48 193 195 20182266 10.1097/MLR. 0b013e3181d51ddf