Point mutations in wchA are responsible for the non-typability of two invasive Streptococcus pneumoniae isolates

Microbiology

Volumn 158, Issue 2, 2012, Pages 338-344

  Melchiorre, Sara ^a   Camilli, Romina ^b   Pietrantoni, Agostina ^b   Moschioni, Monica ^a   Berti, Francesco ^a   Del Grosso, Maria ^b   Superti, Fabiana ^b   Barocchi, Michèle Anne ^a   Pantosti, Annalisa ^a  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GLYCOSYLTRANSFERASE; POLYSACCHARIDE; UNCLASSIFIED DRUG; WCHA PROTEIN;

ARTICLE; BACTEREMIA; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE LOCUS; GENE OVEREXPRESSION; GENE SEQUENCE; HIGH RESOLUTION MAGIC ANGLE SPINNING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; TRANSMISSION ELECTRON MICROSCOPY;

ADULT; AMINO ACID SEQUENCE; BACTERIAL CAPSULES; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; FEMALE; GLYCOSYLTRANSFERASES; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PNEUMOCOCCAL INFECTIONS; POINT MUTATION; SEQUENCE ALIGNMENT; STREPTOCOCCUS PNEUMONIAE;

STREPTOCOCCUS PNEUMONIAE;

EID: 84856718644     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.054270-0     Document Type: Article

References (32)

1. Achen, M. G., Davidson, B. E. & Hillier, A. J. (1986). Construction of plasmid vectors for the detection of streptococcal promoters. Gene 45, 45-49
2. Alloing, G., Martin, B., Granadel, C. & Claverys, J. P. (1998). Development of competence in Streptococcus pneumoniae: pheromone autoinduction and control of quorum sensing by the oligopeptide permease. Mol Microbiol 29, 75-83
3. Andrade, A. L., Franco, C. M., Lamaro-Cardoso, J., André, M. C., Oliveira, L. L., Kipnis, A., Rocha, C. G., Andrade, J. G., Alves, S. L. & other authors (2010). Non-typeable Streptococcus pneumoniae carriage isolates genetically similar to invasive and carriage isolates expressing capsular type 14 in Brazilian infants. J Infect 61, 314-322
4. Arrecubieta, C., López, R. & García, E. (1994). Molecular characterization of cap3A, a gene from the operon required for the synthesis of the capsule of Streptococcus pneumoniae type 3: sequencing of mutations responsible for the unencapsulated phenotype and localization of the capsular cluster on the pneumococcal chromosome. J Bacteriol 176, 6375-6383
5. Austrian, R. (1976). The quellung reaction, a neglected microbiologic technique. Mt Sinai J Med 43, 699-709
6. Bagnoli, F., Moschioni, M., Donati, C., Dimitrovska, V., Ferlenghi, I., Facciotti, C., Muzzi, A., Giusti, F., Emolo, C. & other authors (2008). A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells. J Bacteriol 190, 5480-5492
7. Baldry, S. J., Hinds, J., Gould, K., Lambertsen, L., Hanage, W., Antonio, M., Turner, P., Hermans, P. & Bentley, S. (2009). Sequencing the cps locus of non-typeable Streptococcus pneumoniae isolates. In 9th European Meeting on the Molecular Biology of the Pneumococcus (Europneumo), Bern, Switzerland.
8. Beall, B., McEllistrem, M. C., Gertz, R. E., Jr, Wedel, S., Boxrud, D. J., Gonzalez, A. L., Medina, M. J., Pai, R., Thompson, T. A. & other authors (2006). Pre-and postvaccination clonal compositions of invasive pneumococcal serotypes for isolates collected in the United States in 1999, 2001, and 2002. J Clin Microbiol 44, 999-1017
9. Bentley, S. D., Aanensen, D. M., Mavroidi, A., Saunders, D., Rabbinowitsch, E., Collins, M., Donohoe, K., Harris, D., Murphy, L. & other authors (2006). Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet 2, e31.
10. Brown, E. J., Hosea, S. W. & Frank, M. M. (1983). The role of antibody and complement in the reticuloendothelial clearance of pneumococci from the bloodstream. Rev Infect Dis 5 (Suppl 4), S797-S805.
11. Calix, J. J. & Nahm, M. H. (2010). A new pneumococcal serotype, 11E, has a variably inactivated wcjE gene. J Infect Dis 202, 29-38
12. Carvalho, M. G., Steigerwalt, A. G., Thompson, T., Jackson, D. & Facklam, R. R. (2003). Confirmation of nontypeable Streptococcus pneumoniae-like organisms isolated from outbreaks of epidemic conjunctivitis as Streptococcus pneumoniae. J Clin Microbiol 41, 4415-4417
13. Gentile, M. A., Melchiorre, S., Emolo, C., Moschioni, M., Gianfaldoni, C., Pancotto, L., Ferlenghi, I., Scarselli, M., Pansegrau, W. & other authors (2011). Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain. J Biol Chem 286, 14588-14597
14. Gherardi, G., D'Ambrosio, F., Monaco, M., Camilli, R., De Florio, L., D'Ancona, F., Dicuonzo, G. & Pantosti, A. (2009). Population structure of invasive Streptococcus pneumoniae isolates in Italy prior to the implementation of the 7-valent conjugate vaccine (1999-2003). Eur J Clin Microbiol Infect Dis 28, 99-103
15. Gladstone, R. A., Jefferies, J. M., Faust, S. N. & Clarke, S. C. (2011). Continued control of pneumococcal disease in the UK-the impact of vaccination. J Med Microbiol 60, 1-8
16. Guidolin, A., Morona, J. K., Morona, R., Hansman, D. & Paton, J. C. (1994). Nucleotide sequence analysis of genes essential for capsular polysaccharide biosynthesis in Streptococcus pneumoniae type 19F. Infect Immun 62, 5384-5396
17. Hanage, W. P., Kaijalainen, T., Saukkoriipi, A., Rickcord, J. L. & Spratt, B. G. (2006). A successful, diverse disease-associated lineage of nontypeable pneumococci that has lost the capsular biosynthesis locus. J Clin Microbiol 44, 743-749
18. Hathaway, L. J., Stutzmann Meier, P., Bättig, P., Aebi, S. & Mühlemann, K. (2004). A homologue of aliB is found in the capsule region of nonencapsulated Streptococcus pneumoniae. J Bacteriol 186, 3721-3729
19. Jacques, M. & Gottschalk, M. (1997). Use of monoclonal antibodies to visualize capsular material of bacterial pathogens by conventional electron microscopy. Microsc Microanal 3, 234-238
20. Jarva, H., Janulczyk, R., Hellwage, J., Zipfel, P. F., Björck, L. & Meri, S. (2002). Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H. J Immunol 168, 1886-1894
21. Kolkman, M. A., Morrison, D. A., Van Der Zeijst, B. A. & Nuijten, P. J. (1996). The capsule polysaccharide synthesis locus of Streptococcus pneumoniae serotype 14: identification of the glycosyl transferase gene cps14E. J Bacteriol 178, 3736-3741
22. Kolkman, M. A., van der Zeijst, B. A. & Nuijten, P. J. (1998). Diversity of capsular polysaccharide synthesis gene clusters in Streptococcus pneumoniae. J Biochem 123, 937-945
23. Kreikemeyer, B., Gámez, G., Margarit, I., Giard, J. C., Hammerschmidt, S., Hartke, A. & Podbielski, A. (2011). Genomic organization, structure, regulation and pathogenic role of pilus constituents in major pathogenic streptococci and enterococci. Int J Med Microbiol 301, 240-251
24. Llull, D., Muñoz, R., López, R. & García, E. (1999). A single gene (tts) located outside the cap locus directs the formation of Streptococcus pneumoniae type 37 capsular polysaccharide. Type 37 pneumococci are natural, genetically binary strains. J Exp Med 190, 241-252
25. Moreau, M., Richards, J. C., Perry, M. B. & Kniskern, P. J. (1988). Application of high-resolution n.m.r. spectroscopy to the elucidation of the structure of the specific capsular polysaccharide of Streptococcus pneumoniae type 7F. Carbohydr Res 182, 79-99
26. Park, I. H., Pritchard, D. G., Cartee, R., Brandao, A., Brandileone, M. C. & Nahm, M. H. (2007). Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniae. J Clin Microbiol 45, 1225-1233
27. Pelosi, L., Boumedienne, M., Saksouk, N., Geiselmann, J. & Geremia, R. A. (2005). The glucosyl-1-phosphate transferase WchA (Cap8E) primes the capsular polysaccharide repeat unit biosynthesis of Streptococcus pneumoniae serotype 8. Biochem Biophys Res Commun 327, 857-865
28. Ren, B., Szalai, A. J., Thomas, O., Hollingshead, S. K. & Briles, D. E. (2003). Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae. Infect Immun 71, 75-85
29. Sá-Leão, R., Simões, A. S., Nunes, S., Sousa, N. G., Frazão, N. & de Lencastre, H. (2006). Identification, prevalence and population structure of non-typable Streptococcus pneumoniae in carriage samples isolated from preschoolers attending day-care centres. Microbiology 152, 367-376
30. Waite, R. D., Struthers, J. K. & Dowson, C. G. (2001). Spontaneous sequence duplication within an open reading frame of the pneumococcal type 3 capsule locus causes high-frequency phase variation. Mol Microbiol 42, 1223-1232
31. Waite, R. D., Penfold, D. W., Struthers, J. K. & Dowson, C. G. (2003). Spontaneous sequence duplications within capsule genes cap8E and tts control phase variation in Streptococcus pneumoniae serotypes 8 and 37. Microbiology 149, 497-504
32. Xu, Q., Kaur, R., Casey, J. R., Sabharwal, V., Pelton, S. & Pichichero, M. E. (2011). Nontypeable Streptococcus pneumoniae as an otopathogen. Diagn Microbiol Infect Dis 69, 200-204.