Temporal discrimination thresholds in adult-onset primary torsion dystonia: An analysis by task type and by dystonia phenotype

Journal of Neurology

Volumn 259, Issue 1, 2012, Pages 77-82

  Bradley, D ^a,b   Whelan, R ^b   Kimmich, O ^a   O'Riordan, S ^a   Mulrooney, N ^a   Brady, P ^a   Walsh, R ^a   Reilly, R B ^b   Hutchinson, S ^a   Molloy, F ^c   Hutchinson, M ^a  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c BEAUMONT HOSPITAL   (Ireland)

Author keywords

Dystonia; Endophenotype; Genetics; Temporal discrimination threshold (TDT)

Indexed keywords

ADULT; ADULT ONSET PRIMARY TORSION DYSTONIA; AGED; ARTICLE; BLEPHAROSPASM; CERVICAL DYSTONIA; HUMAN; MAJOR CLINICAL STUDY; MUSICIAN'S DYSTONIA; PHENOTYPE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SPASMODIC DYSPHONIA; TACTILE STIMULATION; TASK PERFORMANCE; TIME PERCEPTION; TORSION DYSTONIA; VISUAL STIMULATION; WRITER'S CRAMP;

ADULT; AGE OF ONSET; AGED; AGING; BASAL GANGLIA DISEASES; BLEPHAROSPASM; DISCRIMINATION (PSYCHOLOGY); DYSPHONIA; DYSTONIA MUSCULORUM DEFORMANS; DYSTONIC DISORDERS; ELECTRIC STIMULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; PHOTIC STIMULATION; PHYSICAL STIMULATION; PSYCHOMOTOR PERFORMANCE; TIME PERCEPTION; TORTICOLLIS; YOUNG ADULT;

EID: 84856698686     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-011-6125-7     Document Type: Article

References (24)

1. HM Waddy NA Fletcher AE Harding CD Marsden 1991 A genetic study of idiopathic focal dystonias Ann Neurol 29 320 324 2042948 10.1002/ana.410290315 1:STN:280:DyaK3M3lsVSitw%3D%3D
2. B Leube KR Kessler T Goecke G Auburger R Benecke 1997 Frequency of familial inheritance among 488 index patients with idiopathic focal dystonia and clinical variability in a large family Mov Disord 12 1000 1006 9399227 10.1002/mds.870120625 1:STN:280:DyaK1c%2FmtFKhtw%3D%3D (Pubitemid 27496780)
3. M Stojanovic D Cvetkovic VS Kostic 1995 A genetic study of idiopathic focal dystonias J Neurol 242 508 511 8530978 10.1007/BF00867421 1:STN:280:DyaK28%2Fjsleltw%3D%3D
4. T Fuchs S Gavarini R Saunders-Pullman D Raymond ME Ehrlich SB Bressman LJ Ozelius 2009 Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia Nat Genet 41 286 288 19182804 10.1038/ng.304 1:CAS:528:DC%2BD1MXht1ehsrg%3D
5. M Hallett 1998 Physiology of dystonia Adv Neurol 78 11 18 9750898 1:STN:280:DyaK1cvitlCksA%3D%3D
6. FM Molloy TD Carr KE Zeuner JM Dambrosia M Hallett 2003 Abnormalities of spatial discrimination in focal and generalized dystonia Brain 126 2175 2182 12821512 10.1093/brain/awg219 1:STN:280:DC%2BD3svitVCjtg%3D%3D (Pubitemid 37432362)
7. S Meunier L Garnero A Ducorps L Mazieres S Lehericy ST du Montcel B Renault M Vidailhet 2001 Human brain mapping in dystonia reveals both endophenotypic traits and adaptive reorganization Ann Neurol 50 521 527 11601503 10.1002/ana.1234 1:STN:280:DC%2BD3MrlsV2htw%3D%3D (Pubitemid 32938897)
8. N Frima J Nasir RA Grunewald 2008 Abnormal vibration-induced illusion of movement in idiopathic focal dystonia: an endophenotypic marker? Mov Disord 23 373 377 18044715 10.1002/mds.21838
9. JP O'Dwyer S O'Riordan R Saunders-Pullman SB Bressman F Molloy T Lynch M Hutchinson 2005 Sensory abnormalities in unaffected relatives in familial adult-onset dystonia Neurology 65 938 940 16186541 10.1212/01.wnl.0000176068. 23983.a8 (Pubitemid 41362148)
10. R Walsh JP O'Dwyer IH Sheikh S O'Riordan T Lynch M Hutchinson 2007 Sporadic adult onset dystonia: sensory abnormalities as an endophenotype in unaffected relatives J Neurol Neurosurg Psychiatry 78 980 983 17702779 10.1136/jnnp.2006.105585 (Pubitemid 47310837)
11. M Fiorio M Gambarin EM Valente P Liberini M Loi G Cossu G Moretto KP Bhatia G Defazio SM Aglioti A Fiaschi M Tinazzi 2007 Defective temporal processing of sensory stimuli in DYT1 mutation carriers: a new endophenotype of dystonia? Brain 130 134 142 17105745 10.1093/brain/awl283 (Pubitemid 46026229)
12. M Fiorio M Tinazzi L Bertolasi SM Aglioti 2003 Temporal processing of visuotactile and tactile stimuli in writer's cramp Ann Neurol 53 630 635 12730997 10.1002/ana.10525 (Pubitemid 36529437)
13. D Bradley R Whelan R Walsh J O'Dwyer R Reilly S Hutchinson F Molloy M Hutchinson 2010 Comparing endophenotypes in adult-onset primary torsion dystonia Mov Disord 25 84 90 19938165
14. D Bradley R Whelan R Walsh RB Reilly S Hutchinson F Molloy M Hutchinson 2009 Temporal Discrimination Threshold: VBM evidence for an endophenotype in adult onset primary torsion dystonia Brain 132 2327 2335 19525326 10.1093/brain/awp156 1:STN:280:DC%2BD1MrotFaksQ%3D%3D
15. SM Rao AR Mayer DL Harrington 2001 The evolution of brain activation during temporal processing Nat Neurosci 4 317 323 11224550 10.1038/85191 1:CAS:528:DC%2BD3MXhsF2ru70%3D (Pubitemid 32194881)
16. C Malapani B Rakitin R Levy WH Meck B Deweer B Dubois J Gibbon 1998 Coupled temporal memories in Parkinson's disease: a dopamine-related dysfunction J Cogn Neurosci 10 316 331 9869707 10.1162/089892998562762 1:STN:280: DyaK1M%2FovVCisA%3D%3D (Pubitemid 28247945)
17. GA Calvert 2001 Crossmodal processing in the human brain: insights from functional neuroimaging studies Cereb Cortex 11 1110 1123 11709482 10.1093/cercor/11.12.1110 1:STN:280:DC%2BD3MnmtlKhug%3D%3D (Pubitemid 33108238)
18. A Scontrini A Conte G Defazio M Fiorio G Fabbrini A Suppa M Tinazzi A Berardelli 2009 Somatosensory temporal discrimination in patients with primary focal dystonia J Neurol Neurosurg Psychiatry 80 1315 1319 19541688 10.1136/jnnp.2009.178236 1:STN:280:DC%2BD1MjmtFynuw%3D%3D
19. N Byl F Wilson M Merzenich M Melnick P Scott A Oakes A McKenzie 1996 Sensory dysfunction associated with repetitive strain injuries of tendinitis and focal hand dystonia: a comparative study J Orthop Sports Phys Ther 23 234 244 8775368 1:STN:280:DyaK28zntFGgtw%3D%3D (Pubitemid 26104254)
20. NN Byl MM Merzenich S Cheung P Bedenbaugh SS Nagarajan WM Jenkins 1997 A primate model for studying focal dystonia and repetitive strain injury: effects on the primary somatosensory cortex Phys Ther 77 269 284 9062569 1:STN:280:DyaK2s3hs1eisA%3D%3D (Pubitemid 27113845)
21. NN Byl MM Merzenich WM Jenkins 1996 A primate genesis model of focal dystonia and repetitive strain injury: I. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys Neurology 47 508 520 8757029 1:STN:280:DyaK28zjs1SisQ%3D%3D (Pubitemid 26324052)
22. A Berardelli JC Rothwell M Hallett PD Thompson M Manfredi CD Marsden 1998 The pathophysiology of primary dystonia Brain 121 1195 1212 9679773 10.1093/brain/121.7.1195 (Pubitemid 28327398)
23. EJ Schicatano MA Basso C Evinger 1997 Animal model explains the origins of the cranial dystonia benign essential blepharospasm J Neurophysiol 77 2842 2846 9163399 1:STN:280:DyaK2szgsF2gsw%3D%3D (Pubitemid 27209245)
24. A Schmidt HC Jabusch E Altenmuller J Hagenah N Bruggemann K Lohmann L Enders PL Kramer R Saunders-Pullman SB Bressman A Munchau C Klein 2009 Etiology of musician's dystonia: familial or environmental? Neurology 72 1248 1254 19349605 10.1212/01.wnl.0000345670.63363.d1 1:STN:280:DC%2BD1M3mt1amuw%3D%3D